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Category: immunology

Dual targeting of p53 and c-MYC selectively eliminates leukaemic stem cells - Nature
Real-time in vivo imaging reveals localised Nrf2 stress responses associated with direct and metabolism-dependent drug toxicity - Scientific Reports
Ischemic Preconditioning Protects Astrocytes against Oxygen Glucose Deprivation Via the Nuclear Erythroid 2-Related Factor 2 Pathway - Translational Stroke Research
Biomechanical forces promote embryonic haematopoiesis - Nature
RAS and RHO families of GTPases directly regulate distinct phosphoinositide 3-kinase isoforms - Cell
Hunger states switch a flip-flop memory circuit via a synaptic AMPK-dependent positive feedback loop - Cell
Genetic tracing via DNGR-1 expression history defines dendritic cells as a hematopoietic lineage - Cell
The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-ë_ locus - Cell
The retinoblastoma binding protein RBP2 is an H3K4 demethylase - Cell
Hijacking the neuronal NMDAR signaling circuit to promote tumor growth and invasion - Cell
Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML - Cell
53BP1 regulates DSB repair using Rif1 to control 5'' end resection - Science
Thalamic miR-338-3p mediates auditory thalamocortical disruption and its late onset in models of 22q11.2 microdeletion - Nature Medicine
Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses - Nature Medicine
Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma - Nature Medicine
Loss of BAP1 function leads to EZH2-dependent transformation - Nature Medicine
Epidermal growth factor regulates hematopoietic regeneration after radiation injury - Nature Medicine
DNA sequencing: generation next-next - Nature Methods
IL-37 requires the receptors IL-18Rë± and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction - Nature Immunology
The PYRIN domain-only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA viruses - Nature Immunology
c-Raf, but not B-Raf, is essential for development of K-Ras oncogene-driven non-small cell lung carcinoma - Cancer Cell
The ALK(F1174L) mutation potentiates the oncogenic activity of MYCN in neuroblastoma - Cancer Cell
Calcification of multipotent prostate tumor endothelium - Cancer Cell
Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling - Nature Cell Biology
Suppression of microRNA activity amplifies IFN-ë_-induced macrophage activation and promotes anti-tumour immunity - Nature Cell Biology
PET imaging of leptin biodistribution and metabolism in rodents and primates - Cell Metabolism
Imaging activity in neurons and glia with a Polr2a-based and cre-dependent GCaMP5G-IRES-tdTomato reporter mouse - Neuron
Sexual divergence in microtubule function: the novel intranasal microtubule targeting SKIP normalizes axonal transport and enhances memory - Molecular Psychiatry
Identification of neurodegenerative factors using translatome-regulatory network analysis - Nature Neuroscience
Diminished KCC2 confounds synapse specificity of LTP during senescence - Nature Neuroscience
AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training - Nature Neuroscience
Fractalkine deficiency markedly reduces macrophage accumulation and atherosclerotic lesion formation in CCR2-/- mice: evidence for independent chemokine functions in atherogenesis - Circulation
TPP1 Blocks an ATR-Mediated Resection Mechanism at Telomeres - Molecular Cell
Inhibition of Tumor Growth and Metastasis in Pancreatic Cancer Models by Interference With CD44v6 Signaling - Gastroenterology
Ca2+ responses in enteric glia are mediated by connexin-43 hemichannels and modulate colonic transit in mice - Gastroenterology
NOS1-derived nitric oxide promotes NF-ë¼B transcriptional activity through inhibition of suppressor of cytokine signaling-1 - Journal of Experimental Medicine
Sprouty2, PTEN, and PP2A interact to regulate prostate cancer progression - Journal of Clinical Investigation
Foxc1 and Foxc2 deletion causes abnormal lymphangiogenesis and correlates with ERK hyperactivation - Journal of Clinical Investigation
NO triggers RGS4 degradation to coordinate angiogenesis and cardiomyocyte growth - Journal of Clinical Investigation
Lack of protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis - Journal of Clinical Investigation
Neurovascular crosstalk between interneurons and capillaries is required for vision - Journal of Clinical Investigation
Targeting mTOR dependency in pancreatic cancer - Gut
Ketone bodies mediate antiseizure effects through mitochondrial permeability transition - Annals of Neurology
Matrix metalloproteinase 3 deletion preserves denervated motor endplates after traumatic nerve injury - Annals of Neurology
Periostin is required for maximal airways inflammation andåÊhyperresponsiveness in mice - Journal of Allergy and Clinical Immunology
Endothelial cell-dependent regulation of arteriogenesis - Circulation Research
Biallelic Mutations in PDE10A Lead to Loss of Striatal PDE10A and a Hyperkinetic Movement Disorder with Onset in Infancy - American Journal of Human Genetics
Transduction of group I mGluR-mediated synaptic plasticity by ë_-arrestin2 signalling - Nature Communications
A novel gene required for male fertility and functional CATSPER channel formation in spermatozoa - Nature Communications
P-Rex1 is required for efficient melanoblast migration and melanoma metastasis - Nature Communications
Inflammation-driven carcinogenesis is mediated through STING - Nature Communications
Mek1/2 MAPK kinases are essential for Mammalian development, homeostasis, and Raf-induced hyperplasia - Developmental Cell
Coordinated actions of actin and BAR proteins upstream of dynamin at endocytic clathrin-coated pits - Developmental Cell
TRPC6 channel translocation into phagosomal membrane augments phagosomal function - Proceedings of the National Academy of Sciences of the United States of America
Ion channel-kinase TRPM7 is required for maintaining cardiac automaticity - Proceedings of the National Academy of Sciences of the United States of America
Notch3 drives development and progression of cholangiocarcinoma - Proceedings of the National Academy of Sciences of the United States of America
Sleeping Beauty screen reveals Pparg activation in metastatic prostate cancer - Proceedings of the National Academy of Sciences of the United States of America
Striosome-dendron bouquets highlight a unique striatonigral circuit targeting dopamine-containing neurons - Proceedings of the National Academy of Sciences of the United States of America
Identification of cancer initiating cells in K-Ras driven lung adenocarcinoma - Proceedings of the National Academy of Sciences of the United States of America
Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation - Proceedings of the National Academy of Sciences of the United States of America
HER2 overcomes PTEN (loss)-induced senescence to cause aggressive prostate cancer - Proceedings of the National Academy of Sciences of the United States of America
Increased apoptosis, p53 up-regulation, and cerebellar neuronal degeneration in repair-deficient Cockayne syndrome mice - Proceedings of the National Academy of Sciences of the United States of America
Cystic fibrosis transmembrane conductance regulator with a shortened R domain rescues the intestinal phenotype of CFTR-/- mice - Proceedings of the National Academy of Sciences of the United States of America
The preproghrelin gene is required for the normal integration of thermoregulation and sleep in mice - Proceedings of the National Academy of Sciences of the United States of America
CYP2R1 is a major, but not exclusive, contributor to 25-hydroxyvitamin D production in vivo - Proceedings of the National Academy of Sciences of the United States of America
STING manifests self DNA-dependent inflammatory disease - Proceedings of the National Academy of Sciences of the United States of America
A human IL10 BAC transgene reveals tissue-specific control of IL-10 expression and alters disease outcome - Proceedings of the National Academy of Sciences of the United States of America
Hv1 proton channels are required for high-level NADPH oxidase-dependent superoxide production during the phagocyte respiratory burst - Proceedings of the National Academy of Sciences of the United States of America
Modified activin receptor IIB ligand trap mitigates ineffective erythropoiesis and disease complications in murine ë_-thalassemia - Blood
FGF signaling facilitates postinjury recovery of mouse hematopoietic system - Blood
Targeting vasculogenesis to prevent progression in multiple myeloma - Leukemia
p120 Catenin Suppresses Basal Epithelial Cell Extrusion in Invasive Pancreatic Neoplasia - Cancer Research
Deregulated estrogen receptor alpha and p53 heterozygosity collaborate in the development of mammary hyperplasia - Cancer Research
STAT3 Blockade Inhibits Radiation-Induced Malignant Progression in Glioma - Cancer Research
Obesity promotes breast cancer by CCL2-mediated macrophage recruitment and angiogenesis - Cancer Research
A novel mouse model that develops spontaneous arthritis and is predisposed towards atherosclerosis - Annals of Rheumatic Diseases
The role of Tcfap2c in tumorigenesis and cancer growth in an activated Neu model of mammary carcinogenesis - Oncogene
In vivo oncogenic conflict triggered by co-existing KRAS and EGFR activating mutations in lung adenocarcinoma - Oncogene
TFAP2C governs the luminal epithelial phenotype in mammary development and carcinogenesis - Oncogene
Mek1/2 gene dosage determines tissue response to oncogenic Ras signaling in the skin - Oncogene
Functions of TAp63 and p53 in restraining the development of metastatic cancer - Oncogene
p53 mutations cooperate with oncogenic Kras to promote adenocarcinoma from pancreatic ductal cells - Oncogene
C-terminal threonines and serines play distinct roles in the desensitization of rhodopsin, a G protein-coupled receptor - Elife
Genetic dissection of Down syndrome-associated congenital heart defects using a new mouse mapping panel - Elife
Hypoxia-induced metabolic stress in retinal pigment epithelial cells is sufficient to induce photoreceptor degeneration - Elife
Sex differences in cerebellar synaptic transmission and sex-specific responses to autism-linked Gabrb3 mutations in mice - Elife
Kindlin1 regulates microtubule function to ensure normal mitosis - Journal of Molecular Cell Biology
Matrix metalloproteinase-20 mediates dental enamel biomineralization by preventing protein occlusion inside apatite crystals - Biomaterials
Disrupted Cortical State Regulation in a Rat Model of Fragile X Syndrome - Cerebral Cortex
Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy - EMBO Molecular Medicine
SPRY2 loss enhances ErbB trafficking and PI3K/AKT signalling to drive human and mouse prostate carcinogenesis - EMBO Molecular Medicine
p21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium - EMBO Molecular Medicine
Differential role of lipocalin 2 during immune complex-mediated acute and chronic inflammation in mice - Arthritis & Rheumatology
Requirement of myeloid cell-specific Fas expression for prevention of systemic autoimmunity in mice - Arthritis & Rheumatology
Role of ë_4* Nicotinic Acetylcholine Receptors in the Habenulo-Interpeduncular Pathway in Nicotine Reinforcement in Mice - Neuropsychopharmacology
Forebrain-specific CRF overproduction during development is sufficient to induce enduring anxiety and startle abnormalities in adult mice - Neuropsychopharmacology
NADPH Oxidase-Dependent NLRP3 Inflammasome Activation and its Important Role in Lung Fibrosis by Multiwalled Carbon Nanotubes - Small
CXCR2 inhibition suppresses acute and chronic pancreatic inflammation - Journal of Pathology
Fibroblast growth factor receptor 3 activation plays a causative role in urothelial cancer pathogenesis in cooperation with Pten loss in mice - Journal of Pathology
Vertebrate Host Susceptibility to Heartland Virus - Emerging Infectious Diseases
Telomere-Internal Double-Strand Breaks Are Repaired by Homologous Recombination and PARP1/Lig3-Dependent End-Joining - Cell Reports
Expression of BCR/ABL p210 from a knockin allele enhances bone marrow engraftment without inducing neoplasia - Cell Reports
Role of angiopoietin-2 in adaptive tumor resistance to VEGF signaling blockade - Cell Reports
Pten loss in Olig2 expressing neural progenitor cells and oligodendrocytes leads to interneuron dysplasia and leukodystrophy - Stem Cells
Target-derived neurotrophins coordinate transcription and transport of bclw to prevent axonal degeneration - Journal of Neuroscience
Fatty Acid-Binding Protein 5 at the Blood-Brain Barrier Regulates Endogenous Brain Docosahexaenoic Acid Levels and Cognitive Function - Journal of Neuroscience
The Angelman syndrome protein Ube3a/E6AP is required for Golgi acidification and surface protein sialylation - Journal of Neuroscience
Homeostatic responses fail to correct defective amygdala inhibitory circuit maturation in fragile X syndrome - Journal of Neuroscience
PIP2-mediated HCN3 channel gating is crucial for rhythmic burst firing in thalamic intergeniculate leaflet neurons - Journal of Neuroscience
Mature mice lacking Rbl2/p130 gene have supernumerary inner ear hair cells and supporting cells - Journal of Neuroscience
The p38ë± MAPK regulates microglial responsiveness to diffuse traumatic brain injury - Journal of Neuroscience
PPARë_ recruitment to active ERK during memory consolidation is required for Alzheimer''s disease-related cognitive enhancement - Journal of Neuroscience
Sensory neuropathy attributable to loss of Bcl-w - Journal of Neuroscience
Circuit-specific intracortical hyperconnectivity in mice with deletion of the autism-associated Met receptor tyrosine kinase - Journal of Neuroscience
Dendritic HCN2 channels constrain glutamate-driven excitability in reticular thalamic neurons - Journal of Neuroscience
A new mouse model for stationary night blindness with mutant Slc24a1 explains the pathophysiology of the associated human disease - Human Molecular Genetics
CREB-activity and nmnat2 transcription are down-regulated prior to neurodegeneration, while NMNAT2 over-expression is neuroprotective, in a mouse model of human tauopathy - Human Molecular Genetics
Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis - Human Molecular Genetics
Lipid-enriched diet rescues lethality and slows down progression in a murine model of VCP-associated disease - Human Molecular Genetics
Loss of GM3 synthase gene, but not sphingosine kinase 1, is protective against murine nephronophthisis-related polycystic kidney disease - Human Molecular Genetics
Glycogen accumulation underlies neurodegeneration and autophagy impairment in Lafora disease - Human Molecular Genetics
AKT regulates NPM dependent ARF localization and p53mut stability in tumors - Oncotarget
The role of apoptosis in immune hyporesponsiveness following AAV8 liver gene transfer - Molecular Therapy
Acute Inhibition of MEK Suppresses Congenital Melanocytic Nevus Syndrome in a Murine Model Driven by Activated NRAS and Wnt Signaling - Journal of Investigative Dermatology
ë±5 and ë±v integrins cooperate to regulate vascular smooth muscle and neural crest functions in vivo - Development
Tropomodulin 1 directly controls thin filament length in both wild-type and tropomodulin 4-deficient skeletal muscle - Development
Phenotypic analysis of mice completely lacking netrin 1 - Development
Endothelial alpha5 and alphav integrins cooperate in remodeling of the vasculature during development - Development
Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development - Development
Fascin 1 is transiently expressed in mouse melanoblasts during development and promotes migration and proliferation - Development
The neuron-specific interleukin-1 receptor accessory protein is required for homeostatic sleep and sleep responses to influenza viral challenge in mice - Brain Behavior and Immunity
Sickness behaviour after lipopolysaccharide treatment in ghrelin deficient mice - Brain Behavior and Immunity
Specific suppression of insulin sensitivity in growth hormone receptor gene-disrupted (GHR-KO) mice attenuates phenotypic features of slow aging - Aging Cell
Sensitization of nociceptive spinal neurons contributes to pain in a transgenic model of sickle cell disease - Pain
Optogenetic release of norepinephrine from cardiac sympathetic neurons alters mechanical and electrical function - Cardiovascular Research
NOX4-derived reactive oxygen species limit fibrosis and inhibit proliferation of vascular smooth muscle cells in diabetic atherosclerosis - Free Radical Biology and Medicine
Fatty acid amide hydrolase is a key regulator of endocannabinoid-induced myocardial tissue injury - Free Radical Biology and Medicine
Chk1 is essential for the development of murine epidermal melanocytes - Pigment Cell and Melanoma Research
Differential effects of NOX4 and NOX1 on immune cell-mediated inflammation in the aortic sinus of diabetic ApoE-/- mice - Clinical Science
Use of a genetically engineered mouse model as a preclinical tool for HER2 breast cancer - Disease Models and Mechanisms
CK2 activity is required for the interaction of FGF14 with voltage-gated sodium channels and neuronal excitability - FASEB Journal
Sustained nitric oxide (NO)-releasing compound reverses dysregulated NO signal transduction in priapism - FASEB Journal
Proceedings of the Second Shanthi V. Sitaraman Intestinal Pathobiology Symposium - Inflammory Bowel Disorder Journal
Cathelicidin suppresses lipid accumulation and hepatic steatosis by inhibition of the CD36 receptor - International Journal of Obesity (Lond)
Intrauterine group A streptococcal infections are exacerbated by prostaglandin E2 - Journal of Immunology
The class A scavenger receptor, macrophage receptor with collagenous structure, is the major phagocytic receptor for Clostridium sordellii expressed by human decidual macrophages - Journal of Immunology
Characterization of human antiviral adaptive immune responses during hepatotropic virus infection in HLA-transgenic human immune system mice - Journal of Immunology
Intrinsic self-DNA triggers inflammatory disease dependent on STING - Journal of Immunology
Beta1 integrin is an adhesion protein for sperm binding to eggs - ACS Chemical Biology
Microglial p38ë± MAPK is critical for LPS-induced neuron degeneration, through a mechanism involving TNFë± - Molecular Neurodegeneration
Fibroblast Growth Factor 14 Modulates the Neurogenesis of Granule Neurons in the Adult Dentate Gyrus - Molecular Neurobiology
Role of ERalpha in the differential response of Stat5a loss in susceptibility to mammary preneoplasia and DMBA-induced carcinogenesis - Carcinogenesis
NOTCH1 regulates matrix gla protein and calcification gene networks in human valve endothelium - Journal of Molecular and Cellular Cardiology
Ectopic expression of the striatal-enriched GTPase Rhes elicits cerebellar degeneration and an ataxia phenotype in Huntington''s disease - Neurobiology of Disease
Mitochondrial dysfunction in an Opa1(Q285STOP) mouse model of dominant optic atrophy results from Opa1 haploinsufficiency - Cell Death Discovery
Protease induced plasticity: matrix metalloproteinase-1 promotes neurostructural changes through activation of protease activated receptor 1 - Scientific Reports
Electroacupuncture in conscious free-moving mice reduces pain by ameliorating peripheral and central nociceptive mechanisms - Scientific Reports
Macrophages form functional vascular mimicry channels in vivo - Scientific Reports
miR-182 Modulates Myocardial Hypertrophic Response Induced by Angiogenesis in Heart - Scientific Reports
Sensory hypo-excitability in a rat model of fetal development in Fragile X Syndrome - Scientific Reports
The astrocytic transporter SLC7A10 (Asc-1) mediates glycinergic inhibition of spinal cord motor neurons - Scientific Reports
Cartilage-Specific Knockout of the Mechanosensory Ion Channel TRPV4 Decreases Age-Related Osteoarthritis - Scientific Reports
Magnetic Resonance Spectroscopy discriminates the response to microglial stimulation of wild type and Alzheimer''s disease models - Scientific Reports
Microfluidic squeezing for intracellular antigen loading in polyclonal B-cells as cellular vaccines - Scientific Reports
Crumbs3 is essential for proper epithelial development and viability - Molelcular and Cellular Biology
Enhanced Cognition and Hypoglutamatergic Signaling in a Growth Hormone Receptor Knockout Mouse Model of Successful Aging - Journals of Gerontology
Primary cancer cell culture: mammary-optimized vs conditional reprogramming - Endocrine Related Cancer
Microglial p38ë± MAPK is a key regulator of proinflammatory cytokine up-regulation induced by toll-like receptor (TLR) ligands or beta-amyloid (Aë_) - Journal of Neuroinflammation
The p38alpha mitogen-activated protein kinase limits the CNS proinflammatory cytokine response to systemic lipopolysaccharide, potentially through an IL-10 dependent mechanism - Journal of Neuroinflammation
Age exacerbates the CCR2/5-mediated neuroinflammatory response to traumatic brain injury - Journal of Neuroinflammation
Deficiency of complement receptors CR2/CR1 in Cr2‰È/‰È mice reduces the extent of secondary brain damage after closed head injury - Journal of Neuroinflammation
Tau downregulates BDNF expression in animal and cellular models of Alzheimer's disease - Neurobiology of Aging
Accelerated protein damage in brains of PIMT+/- mice; a possible model for the variability of cognitive decline in human aging - Neurobiology of Aging
CB䉉 receptor deficiency increases amyloid pathology and alters tau processing in a transgenic mouse model of Alzheimer's disease - Molecular Medicine
Transcriptional dysregulation causes altered modulation of inhibition by haloperidol - Neuropharmacology
In vitro gamma oscillations following partial and complete ablation of ë« subunit-containing GABAA receptors from parvalbumin interneurons - Neuropharmacology
Monitoring cholinergic activity during attentional performance in mice heterozygous for the choline transporter: a model of cholinergic capacity limits - Neuropharmacology
Attenuated p53 activation in tumour-associated stromal cells accompanies decreased sensitivity to etoposide and vincristine - British Journal of Cancer
The ability of an attaching and effacing pathogen to trigger localized actin assembly contributes to virulence by promoting mucosal attachment - Cellular Microbiology
Fatty Acid-Binding Protein 5 Facilitates the Blood-Brain Barrier Transport of Docosahexaenoic Acid - Molecular Pharmaceutics
KISS1R signals independently of Gë±q/11 and triggers LH secretion via the ë_-arrestin pathway in the male mouse - Endocrinology
Reduced melanocortin production causes sexual dysfunction in male mice with POMC neuronal insulin and leptin insensitivity - Endocrinology
Delayed puberty but normal fertility in mice with selective deletion of insulin receptors from Kiss1 cells - Endocrinology
Mechanisms of amylin/leptin synergy in rodent models - Endocrinology
Regulation of brain PPARgamma2 contributes to ketogenic diet anti-seizure efficacy - Experimental Neurology
Preservation of neuromuscular function in symptomatic SOD1-G93A mice by peripheral infusion of methylene blue - Experimental Neurology
Desert hedgehog is a mediator of demyelination in compression neuropathies - Experimental Neurology
BGP-15 Improves Aspects of the Dystrophic Pathology in mdx and dko Mice with Differing Efficacies in Heart and Skeletal Muscle - American Journal of Pathology
The PPARë_ agonist efatutazone increases the spectrum of well-differentiated mammary cancer subtypes initiated by loss of full-length BRCA1 in association with TP53 haploinsufficiency - American Journal of Pathology
The Dendritic Cell Major Histocompatibility Complex II (MHC II) Peptidome Derives from a Variety of Processing Pathways and Includes Peptides with a Broad Spectrum of HLA-DM Sensitivity - Journal of Biological Chemisrty
Hepatic Insulin Resistance Following Chronic Activation of the CREB Coactivator CRTC2 - Journal of Biological Chemisrty
Central Mechanisms Mediating Thrombospondin-4-induced Pain States - Journal of Biological Chemisrty
Purinergic control of hippocampal circuit hyperexcitability in Dravet syndrome - Epilepsia
In vivo ketogenic diet treatment attenuates pathologic sharp waves and high frequency oscillations in in vitro hippocampal slices from epileptic Kv 1.1ë± knockout mice - Epilepsia
Optogenetic stimulation of cholinergic brainstem neurons during focal limbic seizures: Effects on cortical physiology - Epilepsia
Ketogenic diet treatment increases longevity in Kcna1-null mice, a model of sudden unexpected death in epilepsy - Epilepsia
Ketogenic diet treatment abolishes seizure periodicity and improves diurnal rhythmicity in epileptic Kcna1-null mice - Epilepsia
Research tool: Validation of floxed ë±7 nicotinic acetylcholine receptor conditional knockout mice using in vitro and in vivo approaches - Journal of Physiology (London)
Fluorescence recovery after photobleaching reveals regulation and distribution of connexin36 gap junction coupling within mouse islets of Langerhans - Journal of Physiology (London)
Utrophin regulates modal gating of mechanosensitive ion channels in dystrophic skeletal muscle - Journal of Physiology (London)
CLC-3 chloride channels moderate long-term potentiation at Schaffer collateral-CA1 synapses - Journal of Physiology (London)
Physiological and morphological properties of Dbx1-derived respiratory neurons in the pre-Botzinger complex of neonatal mice - Journal of Physiology (London)
Is connexin36 critical for GABAergic hypersynchronization in the hippocampus? - Journal of Physiology (London)
Automated cell-specific laser detection and ablation of neural circuits in neonatal brain tissue - Journal of Physiology (London)
T-bet is essential for Th1-mediated, but not Th17-mediated, CNS autoimmune disease - European Journal of Immunology
CD40 engagement of CD4+ CD40+ T cells in a neo-self antigen disease model ablates CTLA-4 expression and indirectly impacts tolerance - European Journal of Immunology
Lineage tracking of mesenchymal and endothelial progenitors in BMP-induced bone formation - Bone
Activity-dependent neuroprotective protein (ADNP) exhibits striking sexual dichotomy impacting on autistic and Alzheimer's pathologies - Translational Psychiatry
The activin A antagonist follistatin inhibits cystic fibrosis-like lung inflammation and pathology - Immunology and Cell Biology
Mutation-independent rescue of a novel mouse model of Retinitis Pigmentosa - Gene Therapy
Ovarian cycle-linked plasticity of ë«-GABAA receptor subunits in hippocampal interneurons affects ë_ oscillations in vivo - Frontiers in Cellular Neuroscience
Regulation of ethanol intake under chronic mild stress: roles of dopamine receptors and transporters - Frontiers in Behavioral Neuroscience
TIR Domain-Containing Adapter-Inducing Beta Interferon (TRIF) Mediates Immunological Memory against Bacterial Pathogens - Infection and Immunity
SOCS-3 Regulates Alveolar Bone Loss in Experimental Periodontitis - Journal of Dental Research
Skeletal muscle glucose uptake during treadmill exercise in neuronal nitric oxide synthase-ë_ knockout mice - American Journal of Physiology Endocrinology and Metabolism
The absence of 25-hydroxyvitamin D3-1ë±-hydroxylase potentiates the suppression of EAE in mice by ultraviolet light - Journal of Steroid Biochemistry and Molecular Biology
Fibroblast-specific expression of AC6 enhances beta-adrenergic and prostacyclin signaling and blunts bleomycin-induced pulmonary fibrosis - American Journal of Physiology Lung Cellular and Molecular Physiology
Periostin promotes fibrosis and predicts progression in patients with idiopathic pulmonary fibrosis - American Journal of Physiology Lung Cellular and Molecular Physiology
Toll-like receptor 2 mediates mesenchymal stem cell-associated myocardial recovery and VEGF production following acute ischemia-reperfusion injury - American Journal of Physiology Heart and Circulatory Physiology
ApoE deficiency exacerbates the development and sustainment of a semi-chronic K/BxN serum transfer-induced arthritis model - Journal of Translational Medicine
EP2 and EP4 receptors mediate PGE2 induced relaxation in murine colonic circular muscle: pharmacological characterization - Pharmacology Research
Males are from Mars, and females are from Venus: sex-specific fetal brain gene expression signatures in a mouse model of maternal diet-induced obesity - American Journal of Obsterics and Gynecology
Network of brain protein level changes in glutaminase deficient fetal mice - Journal of Proteomics
Neurological Dysfunction in Early Maturity of a Model for Niemann-Pick C1 Carrier Status - Neurotherapeutics
Pharmacologic inhibition of ghrelin receptor signaling is insulin sparing and promotes insulin sensitivity - Journal of Pharmacology and Expreimental Therapeutics
Enhancing eNOS activity with simultaneous inhibition of IKKë_ restores vascular function in Ins2(Akita+/-) type-1 diabetic mice - Laboratory Investigation
Quantitative assessment of pancreatic cancer precursor lesions in IHC-stained tissue with a tissue image analysis platform - Laboratory Investigation
Mice lacking sialyltransferase ST3Gal-II develop late onset obesity and insulin resistance - Glycobiology
c-Met signalling is required for efficient postnatal thymic regeneration and repair - Immunology
Nervous-tissue-specific elimination of microtubule-actin crosslinking factor 1a results in multiple developmental defects in the mouse brain - Molecular and Cellular Neuroscience
Cooperative regulation of neurotransmitter release by Rab3a and synapsin II - Molecular and Cellular Neuroscience
Tissue inducible Lifeact expression allows visualization of actin dynamics in vivo and ex vivo - European Journal of Cell Biology
Mis-expression of the BK K(+) channel disrupts suprachiasmatic nucleus circuit rhythmicity and alters clock-controlled behavior - American Journal of Physiology, Cell Physiology
Delayed in vitro development of Up states but normal network plasticity in Fragile X circuits - European Journal of Neuroscience
Dopamine increases NMDA-stimulated calcium flux in striatopallidal neurons through a matrix metalloproteinase-dependent mechanism - European Journal of Neuroscience
Intact brown adipose tissue thermogenesis is required for restorative sleep responses after sleep loss - European Journal of Neuroscience
Impaired wake-promoting mechanisms in ghrelin receptor-deficient mice - European Journal of Neuroscience
5'-Ectonucleotidase-knockout mice lack non-REM sleep responses to sleep deprivation - European Journal of Neuroscience
RPGR-associated retinal degeneration in human X-linked RP and a murine model - Investigative Ophthalmology and Visual Science
L450W and Q455K Col8a2 knock-in mouse models of Fuchs endothelial corneal dystrophy show distinct phenotypes and evidence for altered autophagy - Investigative Ophthalmology and Visual Science
Altered Refractive Development in Mice With Reduced Levels of Retinal Dopamine - Investigative Ophthalmology and Visual Science
Isoaspartyl protein damage and repair in mouse retina - Investigative Ophthalmology and Visual Science
Reduced ocular blood flow as an early indicator of diabetic retinopathy in a mouse model of diabetes - Investigative Ophthalmology and Visual Science
The D-isoAsp-25 variant of histone H2B is highly enriched in active chromatin: potential role in the regulation of gene expression? - Amino Acids
WDR72 models of structure and function: a stage-specific regulator of enamel mineralization - Matrix Biology
p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas - Developmental Biology
A quantitative method for defining high-arched palate using the Tcof1(+/-) mutant mouse as a model - Developmental Biology
Integrin-ë±5ë_1 is not required for mural cell functions during development of blood vessels but is required for lymphatic-blood vessel separation and lymphovenous valve formation - Developmental Biology
Knockout of the aryl hydrocarbon receptor results in distinct hepatic and renal phenotypes in rats and mice - Toxicology and Applied Pharmacology
MKP1-dependent PTH modulation of bone matrix mineralization in female mice is osteoblast maturation stage specific and involves P-ERK and P-p38 MAPKs - Journal of Endocrinology
Mitogen-activated protein kinase phosphatase 1 regulates bone mass, osteoblast gene expression, and responsiveness to parathyroid hormone - Journal of Endocrinology
Blood-brain barrier impairment in an animal model of MPS III B - PLOS ONE
Neonatal periostin knockout mice are protected from hyperoxia-induced alveolar simplication - PLOS ONE
Neuromuscular junction defects in mice with mutation of dynein heavy chain 1 - PLOS ONE
The nicotinic receptor Alpha7 impacts the mouse lung response to LPS through multiple mechanisms - PLOS ONE
Generation and Characterisation of a Pax8-CreERT2 Transgenic Line and a Slc22a6-CreERT2 Knock-In Line for Inducible and Specific Genetic Manipulation of Renal Tubular Epithelial Cells - PLOS ONE
A neonatal model of intravenous Staphylococcus epidermidis infection in mice <24 h old enables characterization of early innate immune responses - PLOS ONE
Nfatc2 and Tob1 have non-overlapping function in T cell negative regulation and tumorigenesis - PLOS ONE
Smad4 loss synergizes with TGFë± overexpression in promoting pancreatic metaplasia, PanIN development, and fibrosis - PLOS ONE
CRX is a diagnostic marker of retinal and pineal lineage tumors - PLOS ONE
Lamellipodin-Deficient Mice: A Model of Rectal Carcinoma - PLOS ONE
Insulin and Leptin Signaling Interact in the Mouse Kiss1 Neuron during the Peripubertal Period - PLOS ONE
Considerations in the identification of endogenous substrates for protein L-isoaspartyl methyltransferase: the case of synuclein - PLOS ONE
Liver-Specific Deletion of Phosphatase and Tensin Homolog Deleted on Chromosome 10 Significantly Ameliorates Chronic EtOH-Induced Increases in Hepatocellular Damage - PLOS ONE
Comparative Analysis of Pain Behaviours in Humanized Mouse Models of Sickle Cell Anemia - PLOS ONE
Isoaspartate accumulation in mouse brain is associated with altered patterns of protein phosphorylation and acetylation, some of which are highly sex-dependent - PLOS ONE
Generation and behavior characterization of CaMKIIë_ knockout mice - PLOS ONE
Parental diabetes: the Akita mouse as a model of the effects of maternal and paternal hyperglycemia in wildtype offspring - PLOS ONE
Digastric Muscle Phenotypes of the Ts65Dn Mouse Model of Down Syndrome - PLOS ONE
Rapamycin and chloroquine: the in vitro and in vivo effects of autophagy-modifying drugs show promising results in valosin containing protein multisystem proteinopathy - PLOS ONE
A Fine Balance of Dietary Lipids Improves Pathology of a Murine Model of VCP-Associated Multisystem Proteinopathy - PLOS ONE
Cholecystokinin: an excitatory modulator of mitral/tufted cells in the mouse olfactory bulb - PLOS ONE
Mechanism of testosterone deficiency in the transgenic sickle cell mouse - PLOS ONE
Novel marker for the onset of frontotemporal dementia: early increase in activity-dependent neuroprotective protein (ADNP) in the face of Tau mutation - PLOS ONE
Intrinsic susceptibility MRI identifies tumors with ALKF1174L mutation in genetically-engineered murine models of high-risk neuroblastoma - PLOS ONE
The effects of C75, an inhibitor of fatty acid synthase, on sleep and metabolism in mice - PLOS ONE
A reinforcing circuit action of extrasynaptic GABAA receptor modulators on cerebellar granule cell inhibition - PLOS ONE
Cranial irradiation alters the brain's microenvironment and permits CCR2+ macrophage infiltration - PLOS ONE
Deficiency in p38ë_ MAPK fails to inhibit cytokine production or protect neurons against inflammatory insult in in vitro and in vivo mouse models - PLOS ONE
Hilar somatostatin interneurons contribute to synchronized GABA activity in an in vitro epilepsy model - PLOS ONE
RDH10 oxidation of Vitamin A is a critical control step in synthesis of retinoic acid during mouse embryogenesis - PLOS ONE
7 Nicotinic receptor-mediated astrocytic gliotransmitter release: A effects in a preclinical Alzheimer's mouse model - PLOS ONE
Comprehensive analysis of ultrasonic vocalizations in a mouse model of fragile X syndrome reveals limited, call type specific deficits - PLOS ONE
GPR40 and GPR120 fatty acid sensors are critical for postoral but not oral mediation of fat preferences in the mouse - American Journal of Physiology Regulatory, Integrative and Comparative Physiology
P2X7 receptors in body temperature, locomotor activity, and brain mRNA and lncRNA responses to sleep deprivation - American Journal of Physiology Regulatory, Integrative and Comparative Physiology
Sugar-induced cephalic-phase insulin release is mediated by a T1r2+T1r3-independent taste transduction pathway in mice - American Journal of Physiology Regulatory, Integrative and Comparative Physiology
Restricted feeding-induced sleep, activity, and body temperature changes in normal and preproghrelin-deficient mice - American Journal of Physiology Regulatory, Integrative and Comparative Physiology
Spontaneous sleep and homeostatic sleep regulation in ghrelin knockout mice - American Journal of Physiology Regulatory, Integrative and Comparative Physiology
SOD1-G93A mice exhibit muscle-fiber-type-specific decreases in glucose uptake in the absence of whole-body changes in metabolism - Neuro-degenerative Diseases
Effects of stimulus salience on touchscreen serial reversal learning in a mouse model of fragile X syndrome - Behavioral Brain Research
Sustained attention in mice: expanding the translational utility of the SAT by incorporating the Michigan Controlled Access Response Port (MICARP) - Behavioral Brain Research
A novel role for the immunophilin FKBP52 in motor coordination - Behavioral Brain Research
Neuronal nitric oxide synthase and NADPH oxidase interact to affect cognitive, affective, and social behaviors in mice - Behavioral Brain Research
Measures of bulbar and spinal motor function, muscle innervation, and mitochondrial function in ALS rats - Behavioral Brain Research
Spatial frequency threshold and contrast sensitivity of an optomotor behavior are impaired in the Ins2Akita mouse model of diabetes - Behavioral Brain Research
Molecular and behavioral profiling of Dbx1-derived neurons in the arcuate, lateral and ventromedial hypothalamic nuclei - Neural Development
Common and unique genetic interactions of the poly(ADP-ribose) polymerases PARP1 and PARP2 with DNA double-strand break repair pathways - DNA Repair
In Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice - Drug Metabolism and Disposition
Pharmacokinetics of oral D-serine in D-amino acid oxidase knockout mice - Drug Metabolism and Disposition
Separation of function for classical and ganglion cell photoreceptors with respect to circadian rhythm entrainment and induction of photosomnolence - Neuroscience
Activation of the Wnt/ë_-catenin signaling cascade after traumatic nerve injury - Neuroscience
Distinct mechanisms of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine resistance revealed by transcriptome mapping in mouse striatum - Neuroscience
Nuclear Thioredoxin-1 Overexpression Attenuates Alcohol-Mediated Nrf2 Signaling and Lung Fibrosis - Alcoholism Clinical and Experimental Research
Effects of Gabra2 Point Mutations on Alcohol Intake: Increased Binge-Like and Blunted Chronic Drinking by Mice - Alcoholism Clinical and Experimental Research
Galanin knockout mice show disturbances in ethanol consumption and expression of hypothalamic peptides that stimulate ethanol intake - Alcoholism Clinical and Experimental Research
Hepatitis B virus regulatory HBx protein binding to DDB1 is required but is not sufficient for maximal HBV replication - Virology
Fragile X mental retardation protein regulates olfactory sensitivity but not odorant discrimination - Chemical Senses
Salty taste deficits in CALHM1 knockout mice - Chemical Senses
Normal Taste Acceptance and Preference of PANX1 Knockout Mice - Chemical Senses
Heightened avidity for trisodium pyrophosphate in mice lacking Tas1r3 - Chemical Senses
Ectopic POU5F1 in the male germ lineage disrupts differentiation and spermatogenesis in mice - Reproduction
Comprehensive motor testing in Fmr1-KO mice exposes temporal defects in oromotor coordination - Behavioral Neuroscience
Aryl hydrocarbon receptor knockout rats are insensitive to the pathological effects of repeated oral exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin - Journal of Applied Toxicology
Sildenafil promotes eNOS activation and inhibits NADPH oxidase in the transgenic sickle cell mouse penis - Journal of Sexual Medicine
Post-translational inactivation of endothelial nitric oxide synthase in the transgenic sickle cell mouse penis - Journal of Sexual Medicine
Extracellular sodium and potassium levels modulate cardiac conduction in mice heterozygous null for the Connexin43 gene - Pflugers Archiv - European Journal of Physiology
Astrocytic group I mGluR-dependent potentiation of astrocytic glutamate and potassium uptake - Journal of Neurophysiology
pigk Mutation underlies macho behavior and affects Rohon-Beard cell excitability - Journal of Neurophysiology
PACAP modulation of calcium ion activity in developing granule cells of the neonatal mouse olfactory bulb - Journal of Neurophysiology
Impact of inhibitory constraint of interneurons on neuronal excitability - Journal of Neurophysiology
Intragastric fat self-administration is impaired in GPR40/120 double knockout mice - Physiology and Behavior
MCH receptor deletion does not impair glucose-conditioned flavor preferences in mice - Physiology and Behavior
Ghrelin signaling is not essential for sugar or fat conditioned flavor preferences in mice - Physiology and Behavior
Macronutrient selection by seven inbred mouse strains and three taste-related knockout strains - Physiology and Behavior
Sucrose-conditioned flavor preferences in sweet ageusic T1r3 and Calhm1 knockout mice - Physiology and Behavior
Retinal macroglia changes in a triple transgenic mouse model of Alzheimer's disease - Experimental Eye Research
Intact Toll-like receptor 9 signaling in neutrophils modulates normal thrombogenesis in mice - Journal of Vasuclar Surgery
Morphine-induced antinociception and reward in humanized mice expressing the mu opioid receptor A118G polymorphism - Brain Research Bulletin
Altered gamma oscillations during pregnancy through loss of ë« subunit-containing GABA(A) receptors on parvalbumin interneurons - Frontiers in Neural Circuits
Severe drug-induced repetitive behaviors and striatal overexpression of VAChT in ChAT-ChR2-EYFP BAC transgenic mice - Frontiers in Neural Circuits
Distinct roles of synaptic and extrasynaptic GABAAreceptors in striatal inhibition dynamics - Frontiers in Neural Circuits
Cerebellar Nuclei Neurons Show Only Small Excitatory Responses to Optogenetic Olivary Stimulation in Transgenic Mice: In Vivo and In Vitro Studies - Frontiers in Neural Circuits
Conditional knockout of myocyte focal adhesion kinase abrogates ischemic preconditioning in adult murine hearts - Journal of American Heart Association
Reorganization of circuits underlying cerebellar modulation of prefrontal cortical dopamine in mouse models of autism spectrum disorder - Cerebellum
E-prostanoid 2 receptor signaling suppresses lung innate immunity against Streptococcus pneumoniae - Prostaglandins Other Lipid Mediators
Non-invasive quantification of brain tumor-induced astrogliosis - BMC Neuroscience
Suppression of brain cholesterol synthesis in male Mecp2-deficient mice is age dependent and not accompanied by a concurrent change in the rate of fatty acid synthesis - Brain Research
Long-term improvements in sensory inhibition with gestational choline supplementation linked to 7 nicotinic receptors through studies in Chrna7 null mutation mice - Brain Research
Taste dysfunction in BTBR mice due to a mutation of Itpr3, the inositol triphosphate receptor 3 gene - Physiological Genomics
Involvement of T1R3 in calcium-magnesium taste - Physiological Genomics
Lipoprotein(a) and vitamin C impair development of breast cancer tumors in Lp(a)+; Gulo-/- mice - International Journal of Oncology
Ascorbate supplementation inhibits growth and metastasis of B16FO melanoma and 4T1 breast cancer cells in vitamin C-deficient mice - International Journal of Oncology
Inhibition of neuronal p38ë±, but not p38ë_ MAPK, provides neuroprotection against three different neurotoxic insults - Journal of Molecular Neuroscience
Abstracts of the 10th International Symposium on VIP-PACAP and Related Peptides. December 13-16, 2011. Eilat, Israel - Journal of Molecular Neuroscience
Lentiviral-based approach for the validation of cancer therapeutic targets in vivo - BioTechniques
Intravital live cell triggered imaging system reveals monocyte patrolling and macrophage migration in atherosclerotic arteries - Journal of Biomedical Optics
Knockout of p11 attenuates the acquisition and reinstatement of cocaine conditioned place preference in male but not in female mice - Synapse
Evaluation of [å_‰üF]PFH PET renography to predict future disease progression in a rat model of autosomal dominant polycystic kidney disease - Nuclear Medicine and Biology
Quantification of pain in sickle mice using facial expressions and body measurements - Blood Cells, Molecules, and Diseases
Utrophin suppresses low frequency oscillations and coupled gating of mechanosensitive ion channels in dystrophic skeletal muscle - Channels (Austin)
A progressive translational mouse model of human valosin-containing protein disease: the VCP(R155H/+) mouse - Muscle Nerve
Circadian rhythmicity in serotonin transporter knockout mice - Life Sciences
Protection against vascular leak in neprilysin transgenic mice with complexåÊoverexpressionåÊpattern - Transgenic Research
A germline-competent embryonic stem cell line from NOD.Cg-Prkdc ( scid ) Il2rg ( tm1Wjl )/SzJ (NSG) mice - Transgenic Research
Effects of SB-269970, a 5-HT7 receptor antagonist, in mouse models predictive of antipsychotic-like activity - Behavioral Pharmacology
Inducible cell labeling and lineage tracking during fracture repair - Development, Growth, and Differentiation
Global gene expression profiling in R155H knock-in murine model of VCP disease - Clinical Transltional Science
ZASC1 knockout mice exhibit an early bone marrow-specific defect in murine leukemia virus replication - Virology Journal
Anticonvulsant effects of the selective melatonin receptor agonist ramelteon - Epilepsy and Behavior
Prenatal ablation of nicotinic receptor alpha7 cell lineages produces lumbosacral spina bifida the severity of which is modified by choline and nicotine exposure - American Journal of Medical Genetics Part A
Megaesophagus in a line of transgenic rats: a model of achalasia - Veterinary Pathology
Increased intake of ethanol and dietary fat in galanin overexpressing mice - Alcohol
Improved insulin sensitivity and metabolic flexibility in ghrelin receptor knockout mice - Regulatory Peptides
Bacterial load and inflammation in fetal tissues is not dependent on IL-17a or IL-22 in 10-14 day pregnant mice infected with Listeria monocytogenes - Microbial Pathogenesis
Multiple ERbeta antisera label in ERbeta knockout and null mouse tissues - Journal of Neuroscience Methods
Prediction of death in the SMNëÓ7 mouse model of spinal muscular atrophy: insight into disease stage and progression - Journal of Neuroscience Methods
Activation of the NLRP3 Inflammasome Is Associated with Valosin-Containing Protein Myopathy - Inflammation
Attenuated Salmonella enterica Typhimurium reduces tumor burden in an autochthonous breast cancer model - Anticancer Research
Maneb causes pro-oxidant effects in the hippocampus of Nrf2 knockout mice - Environ.mental Toxicology and Pharmacology
Osteopontin does not mitigate cisplatin ototoxicity or nephrotoxicity in adult mice - Otolaryngology - Head and Neck Surgery
Relationship between circadian period and body size in the tau-mutant golden hamster - Canadian Journal of Physiology and Pharmacology
A comparative assessment of the cytotoxicity and nitric oxide reducing ability of resveratrol, pterostilbene and piceatannol in transformed and normal mouse macrophages - Drug and Chemical Toxicology
Cannabinoid receptor-specific mechanisms to alleviate pain in sickle cell anemia via inhibition of mast cell activation and neurogenic inflammation - Haematologica
Huntingtin promotes mTORC1 signaling in the pathogenesis of Huntington's disease - Science Signaling
SLC26A4 targeted to the endolymphatic sac rescues hearing and balance in Slc26a4 mutant mice - PLOS Genetics
Interaction between Foxc1 and Fgf8 during mammalian jaw patterning and in the pathogenesis of syngnathia - PLOS Genetics
Transient Loss of Protection Afforded by a Live Attenuated Non-typhoidal Salmonella Vaccine in Mice Co-infected with Malaria - PLOS Neglected Tropical Diseases
Conditional deletion of caspase-8 in macrophages alters macrophage activation in a RIPK-dependent manner - Arthritis Research and Therapy
Short telomeres initiate telomere recombination in primary and tumor cells - PLOS Genetics
Small-molecule nociceptin receptor agonist ameliorates mast cell activation and pain in sickle mice - Haematologica
Ventral prostate fibrosis in the Akita mouse is associated with macrophage and fibrocyte infiltration - Journal of Diabetes Research
Salmonella enterica Typhimurium as a tumor-targeting immunotherapy vector - Thesis
How serotonin system alterations influence emotion-and cognition-related behaviors - Thesis
Neuron to microglia communication; a study of CX3CL1 signaling implications in cognitive function, inflammation, and neurodegeneration - Thesis
Investigation of the functional and structural role of podosomes in megakaryocytes - Thesis
Role of -Glucuronidase in the Chemopreventive Efficacy of Oral Curcumin: A Prodrug Hypothesis - Thesis
The Role of the Dopamine D1 Receptor in Cognition - Thesis
Role of Astrocytes in Ischemic Preconditioning-Induced Neuroprotection - Thesis
Functional characterisation of driver events in ovarian clear cell carcinoma - Thesis
Defining the role of Notch Signalling in Intrahepatic Cholangiocarcinoma - Thesis
Neuronal cicuits and reinforcement mechanisms underlying feeding behaviour - Thesis
Regulation of striatal medium spiny neuron GABAA receptor mediated tonic current - Thesis
COMBINATION IMMUNOTHERAPY TARGETING IMMUNOSUPPRESSIVE SIGNALS IN THE TUMOR MICROENVIRONMENT PREVENTS CANCER PROGRESSION - Thesis
Serotonergic Modulation of Glutamate Transmission: Bridging Two Theories of Depression - Thesis
THE ROLE OF PPAR- IN TROPHOBLAST LAYER DYNAMICS - Thesis
Defining the functional role of laminin isoforms in the regulation of the adult hepatic progenitor cell - Thesis
More than a License to Kill: Immune Regulation of Crohn's Disease by Natural Killer Cell and Its Clinical Implication - Thesis
Assessment of hepatic micronutrient disruption and the hepatotoxicity of 3, 3', 4, 4', 5-pentachlorobiphenyl (PCB126) - Thesis
Neuropilin-2 in pancreatic cancer and Semaphorin-3F as a treatment - Thesis
Cannabinoid CB1R Receptor Mediates Metabolic Syndrome in Models of Circadian and Glucocorticoid Dysregulation - Thesis
NEUROPILIN 2 EXPRESSION AND FUNCTION IN - Thesis
The role of Netrin-1 in semicircular canal morphogenesis - Thesis
The Role of Serotonin in the Development of Psychiatric Disorders: Studies on Drug Dependence and Anxiety-like Behaviour Following the Genetic Reduction of the - Thesis
Examining and improving the chemopreventive efficacy of curcumin - Thesis
RON Over-expression Induces Acinar-Ductal Metaplasia and Accelerates Tumorigenesis in a Kras Mutant Mouse Model of Pancreatic Cancer - Thesis
Study of functions of shelterins and telomerase in aging and nuclear reprograming - Thesis
The role of FGFR3 mutation in tumour initiation, progression and invasion of urothelial cell carcinoma in mice - Thesis
Requirement for fibroblast growth factor receptor 1 in hematopoietic stem cells under stress but not during homeostasis - Thesis
The Mechanism of Neuroprotection Mediated By Nicotinamide Mononucleotide Adenylyl Transferase (NMNAT) - Thesis
Investigating the role of caspase cleavage of ROCK1 in tissue homeostasis and tumour development - Thesis
The epithelial-mesenchymal transition factor SNAIL paradoxically enhances reprogramming - Stem Cell Reports
Investigating downstream effectors of KRas signalling in vivo: Dusp6 and Fra1 - Thesis
In vivo characterization of pituitary adenylate cyclase-activating polypeptide in mouse olfactory epithelium - Thesis
Kiss 1 neurons and metabolic sensing - Thesis
Sex differences in the cardiac beta-adrenergic receptor contractile response - Thesis
Nutraceutical Antioxidants and Their Therapeutic Potential in Neurodegeneration - Thesis
AN INVESTIGATION INTO THE ROLE OF IRON, COPPER, AND GENDER IN A TRANSGENIC MOUSE MODEL OF ALZHEIMER'S DISEASE. - Thesis
Host cell factors involved in retrovirus replication and disease pathogenesis - Thesis
The mechanisms of reversal of refractory dysplasia in the salivary gland: Testing the role of p53, RXR and PPARgamma agonists, and PD0332991 - Thesis
Modulation of oncogenic transformation by Raf proteins - Thesis
The Effects of Specialized Proresolving Lipid Mediators on B Lymphocyte Function: Implications for B Cell Differentiation and Antibody Production - Thesis
Role of checkpoint kinase 1 in malignant melanoma - Thesis
Mechanisms of epithelial cell cancer generation: genetic risk factors on cancer progression investigated using in vivo models and at a single cell level - Thesis
p53 loss and Kras mutation in an invasive murine model of colorectal cancer - Thesis
Mechanisms that control the growth of cells in the presence of replication stress - Thesis
Disruption of Abi1/Hssh3bp1 expression induces prostatic intraepithelial neoplasia in the conditional Abi1/Hssh3bp1 KO mice - Oncogenesis
Regulation of DMD pathology by an ankyrin-encoded miRNA - Skeletal Muscle
CNOT3-Dependent mRNA Deadenylation Safeguards the Pluripotent State - Stem Cell Reports
Pericyte structure and distribution in the cerebral cortex revealed by high-resolution imaging of transgenic mice - Neurophotonics
Transcription factor activator protein 2C and downstream redox biology effectors in development and carcinogenesis - Thesis
Crosstalk between the canonical NF-B and Notch signaling pathways inhibits Ppar expression and promotes pancreatic cancer progression in mice - The Journal of Clinical Investigation‰
Altered AIB1 or AIB13 expression impacts ER effects on mammary gland stromal and epithelial content - Molecular Endocrinology
Diphtheria toxin-mediated ablation of lymphatic endothelial cells results in progressive lymphedema - JCI Insight
Role of the Regulator of G protein Signaling 4 in renal ischemic reperfusion injury and repair - Thesis
Mapping Functional Brain Activation Using [14 C]-Iodoantipyrine in Male Serotonin Transporter Knockout Mice - PLOS ONE
Reduction in hSOD1 copy number significantly impacts ALS phenotype presentation in G37R (line 29) mice: implications for the assessment of putative therapeutic agents - Journal of Negative Results in Biomedicine
Biosynthesis of the major brain gangliosides GD1a and GT1b - Glycobiology
jul~ z, q. dol - Thesis
The Role of Dietary Copper and Zinc on Inflammation and Oxidative Stress in Alzheimer's Disease - Thesis
An Investigation into the Role of Copper Deficiency and Zinc in a Mouse Model of Early Onset Alzheimer's Disease. - Thesis
SELECTIVE MOLECULAR MODIFICATION TO CALCIUM CONDUCTANCE DOMAINS OF NMDA RECEPTOR GLUN2 SUBUNITS REGULATES MATURATION OF - Thesis
The role of neuropilin 2 in physiological and pathological angiogenesis - Thesis
Genome wide gene expression analysis of two ENU mouse models of major mental illness - Thesis
Identification of a maleimide-based glycogen synthase kinase-3 (GSK-3) inhibitor, BIP-135, that prolongs the median survival time of 7 SMA KO mouse model of - ACS Chemical Neuroscience
Receptor-Dependent Phagocytosis of Clostridium sordellii by Human Decidual Macrophages - Thesis
Contribution of Organic Cation Transporter 2 (OCT2) to CisplatinInduced Nephrotoxicity - Clinical Pharmacology &amp; Therapeutics
Synaptic molecular imaging in spared and deprived columns of mouse barrel cortex with array tomography - Scientific Data
Genetic Pharmacotherapy as an Early CNS Drug Development Strategy: Testing Glutaminase Inhibition for Schizophrenia Treatment in Adult Mice - Frontiers in Systems Neuroscience
Novel tubulin and tau neuroprotective fragments sharing structural similarities with the drug candidate NAP (Davuentide) - Journal of Alzheimers Disease
Deregulated estrogen receptor alpha-initiated preneoplasia and its progression: Role of STAT5A and cyclin D1 - Thesis
Human ApoE ëµ4 alters circadian rhythm activity, IL-1ë_, and GFAP in CRND8 mice - J. Alzheimers Dis.
The role of neuropilin 2 in physiological and pathological angiogenesis and lymphangiogenesis - Thesis
Further validation to support clinical translation of [(18)F]FTC-146 for imaging sigma-1 receptors - EJNMMI Res
Does Prenatal Valproate Interact with a Genetic Reduction in the Serotonin Transporter? A Rat Study on Anxiety and Cognition - Frontiers in Neuroscience
In vivo axonal transport deficits in a mouse model of fronto-temporal dementia - Neuroimage Clinical
Impact of the loss of caveolin-1 on lung mass and cholesterol metabolism in mice with and without the lysosomal cholesterol transporter, Niemann-Pick type C1 - Biochimica et Biophysica Acta Journal (BBA)
Quantitative Analysis of Supporting Cell Subtype Labeling Among CreER Lines in the Neonatal Mouse Cochlea - Journal of the Association for Research in Otolaryngology (JARO)
A Cystine-Rich Whey Supplement (Immunocal(å¨)) Delays Disease Onset and Prevents Spinal Cord Glutathione Depletion in the hSOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis - Antioxidants (Basel)
Deletion of the type-1 interferon receptor in APPSWE/PS1ëÓE9 mice preserves cognitive function and alters glial phenotype - Acta Neuropathologica Communications
Brain-specific interleukin-1 receptor accessory protein in sleep regulation - Journal of Applied Physiology
Modulating dopamine release by optogenetics in transgenic mice reveals terminal dopaminergic dynamics - Neurophotonics
Early exposure to environmental toxin contributes to neuronal vulnerability and axonal pathology in a model of familial ALS - Neuroscience &amp; Medicine
B cell and/or autoantibody deficiency do not prevent neuropsychiatric disease in murine systemic lupus erythematosus - Journal of Neuroinflammation
Community pharmacists' experience with pharmacogenetic testing - Journal of American Pharmicists Association (2003)
Metallothionein's role in PCB126 induced hepatotoxicity and hepatic micronutrient disruption - Toxicology Reports
Interaction of growth hormone receptor/binding protein gene disruption and caloric restriction for insulin sensitivity and attenuated aging - F1000Research
Ganglioside accumulation in glia during neurodegeneration and glial activation in the developing brain: Comparison between wild-type and GM2/GD2 synthase knock - Journal of Lipid Research
Identification of the pre-B̦tzinger complex inspiratory center in calibrated sandwich slices from newborn mice with fluorescent Dbx1 interneurons - Physiology Reports
Are Researchers Making the Most of Germ-Free Models? - Taconic
Generation of Kcnma1fl-tdTomato, a conditional deletion of the BK channel ë± subunit in mouse - Physiology Reports
Association of Over-Expressed Estrogen Receptor Alpha with Development of Tamoxifen Resistant Hyperplasia and Adenocarcinomas in Genetically Engineered Mice - Anatomy &amp; Physiology : Current Research
Administration of CoQ 10 analogue ameliorates dysfunction of the mitochondrial respiratory chain in a mouse model of Angelman syndrome - Neurobiology of Disease
Pendrin gene ablation alters ENaC subcellular distribution and open probability - American Journal of Physiology Renal Physiology
The role of the 7 subunit of the nicotinic acetylcholine receptor in the acute toxicosis of methyllycaconitine in mice - Journal of Applied Toxicology
Type II Cochlear Ganglion Neurons Do Not Drive the Olivocochlear Reflex: Re-Examination of the Cochlear Phenotype in Peripherin Knock-Out Mice - eNeuro
The CDK4/6 inhibitor PD0332991 reverses epithelial dysplasia associated with abnormal activation of the cyclin-CDK-Rb pathway - Cancer Prev Res (Phila)
Altered Responses to Cold Environment in Urocortin 1 and Corticotropin-Releasing Factor Deficient Mice - Physiology Journal
Obesity and diabetes cause cognitive dysfunction in the absence of accelerated ë_-amyloid deposition in a novel murine model of mixed or vascular dementia - Acta Neuropathologica Communications
Short Course - Pathobiology &amp; Phenotyping
2006 ALA Survey on Industrial Laboratory Automation - Journal of the Association for Laboratory Automation
Effects of cell-type specific hIL-10 expression on disease susceptibility (51.5) - The Journal of Immunology
ATP and the purine type 2 X7 receptor affect sleep - Journal of Applied Physiology
Ascorbate depletion increases growth and metastasis of melanoma cells in vitamin C deficient mice - Experimental Oncology
Nitric oxide reduces Cl‰È absorption in the mouse cortical collecting duct through an ENaC-dependent mechanism - American Journal of Physiology
Program and Abstracts of the 10th Transgenic Technology Meeting (TT2011) - Transgenic Research
Loss of Jagged1 in renin progenitors leads to focal kidney fibrosis - Physiology Reports
An LHX1-Regulated Transcriptional Network Controls Sleep/Wake Coupling and Thermal Resistance of the Central Circadian Clockworks - Current Biology
Injectable, Guest-Host Assembled Polyethylenimine Hydrogel for siRNA Delivery - Biomacromolecules
IL-15 Enables Septic Shock by Maintaining NK Cell Integrity and Function - Journal of Immunology
Interleukin 37 expression in mice alters sleep responses to inflammatory agents and influenza virus infection - Neurobiology of Sleep and Circadian Rhythms
Distinct Brca1 Mutations Differentially Reduce Hematopoietic Stem Cell Function - Cell Reports
Experimental Design and Data Analysis Issues Contribute to Inconsistent Results of C-Bouton Changes in Amyotrophic Lateral Sclerosis - eNeuro
Complement C5a receptor is the key initiator of neutrophil adhesion igniting immune complex‰ÛÒinduced arthritis - Science Immunology
Tumor-Infiltrating Merkel Cell Polyomavirus-Specific T Cells Are Diverse and Associated with Improved Patient Survival. - Cancer Immunology Research
Coordination by Cdc42 of Actin, Contractility, and Adhesion for Melanoblast Movement in Mouse Skin - Current Biology
CatSperë¦ regulates the structural continuity of sperm Ca(2+) signaling domains and is required for normal fertility - Elife
Speed and segmentation control mechanisms characterized in rhythmically-active circuits created from spinal neurons produced from genetically-tagged embryonic stem cells - Elife
Frequent Zika Virus Sexual Transmission and Prolonged Viral RNA Shedding in an Immunodeficient Mouse Model - Cell Reports
Two modes of enteric gliotransmission differentially affect gut physiology - Glia
Epileptiform activity and behavioral arrests in mice overexpressing the calcium channel subunit ë±2ë«-1 - Neurobiology of Disease
Hemoglobin induced cell trauma indirectly influences endothelial TLR9 activity resulting in pulmonary vascular smooth muscle cell activation - PLOS ONE
Ablation of Cyclophilin D Results in an Activation of FAK, Akt and ERK Pathways in the Mouse Heart - Journal of Cellular Biochemistry
Action Potentials and Ion Conductances in Wild-type and CALHM1-knockout Type II Taste Cells - Journal of Neurophysiology
A Longitudinal Investigation into the Effect of Zn and Cu on Spatial Learning/Memory and Social Preference in a Mouse Model of LOAD - Thesis
Reduced bioavailable manganese causes striatal urea cycle pathology in Huntington's disease mouse model - Biochimica et Biophysica Acta
Parvalbumin Interneurons Modulate Striatal Output and Enhance Performance during Associative Learning - Neuron
Supporting cells remove and replace sensory receptor hair cells in a balance organ of adult mice - Elife
Mebendazole and a non-steroidal anti-inflammatory combine to reduce tumor initiation in a colon cancer preclinical model - Oncotarget
Mertk on tumor macrophages is a therapeutic target to prevent tumor recurrence following radiation therapy - Oncotarget
Abnormal Capillary Vasodynamics Contribute to Ictal Neurodegeneration in Epilepsy - Scientific Reports
Absence of a gestational diabetes phenotype in the LepRdb/+ mouse is independent of control strain, diet, misty allele, or parity - Scientific Reports
Adrenocorticotropic hormone protects learning and memory function in epileptic Kcna1-null mice - Neuroscience Letters
An anthocyanin-enriched extract from strawberries delays disease onset and extends survival in the hSOD1(G93A) mouse model of amyotrophic lateral sclerosis - Nutritional Neuroscience
Responsiveness of Brca1 and Trp53 Deficiency-Induced Mammary Preneoplasia to Selective Estrogen Modulators versus an Aromatase Inhibitor in Mus musculus - Cancer Prevention Research (Phila)
Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice - Nature
Modulating the therapeutic response of tumours to dietary serine and glycine starvation - Nature
Phosphorylation of Rab-coupling protein by LMTK3 controls Rab14-dependent EphA2 trafficking to promote cell:cell repulsion - Nature Communications
Embryonic transcription factor expression in mice predicts medial amygdala neuronal identity and sex-specific responses to innate behavioral cues - Elife
Astrocytes modulate thalamic sensory processing via mGlu2 receptor activation - Neuropharmacology
Investigating the Role of Serotonin in Methamphetamine Psychosis: Unaltered Behavioral Effects of Chronic Methamphetamine in 5-HT1A Knockout Mice - Frontiers in Psychiatry
Embryonic Transcription Factor Expression Predicts Neuronal Identity and Innate Behavioral Activation Patterns in the Limbic System - Thesis
Protease induced plasticity: Matrix metalloproteinase-1 activation of protease activated receptor 1 induces neuronal structural plasticity - Thesis
PPARë_-pERK interaction restores memory consolidation in an Alzheimer's disease model - Thesis
Chemopreventive efficacy of curcumin-loaded PLGA microparticles in a transgenic mouse model of HER-2-positive breast cancer - Drug Delivery and Translational Research
Treadmill exercise delays the onset of non-motor behaviors and striatal pathology in the CAG140 knock-in mouse model of Huntington's disease. - Neurobiology of Disease
The role of the brown adipose tissue in ë_3-adrenergic receptor activation-induced sleep, metabolic and feeding responses - Scientific Reports
Development of an inducible mouse model of iRFP713 to track recombinase activity and tumour development in vivo - Scientific Reports
Proteomic profiling of the hypothalamus in two mouse models of narcolepsy - Proteomics
Phosphorus Taste Involves T1R2 and T1R3 - Chemical Senses
Enkephalin levels and the number of neuropeptide Y-containing interneurons in the hippocampus are decreased in female cannabinoid-receptor 1 knock-out mice - Neuroscience Letters
Targeting Tumour Angiogenesis in Colorectal Cancer Liver Metastases - Thesis
The Na(+)/Ca(2+), K(+) exchanger NCKX4 is required for efficient cone-mediated vision - Elife
Treadmill exercise delays the onset of non-motor behaviors and striatal pathology in the CAG 140 knock-in mouse model of Huntington's disease - Neurobiology of Disease
PPARgamma agonists rescue increased phosphorylation of FGF14 at S226 in the Tg2576 mouse model of Alzheimer's disease - Experimental Neurology
Role of ERë± in Mediating Female Uterine Transcriptional Responses to IGF1 - Endocrinology
Functional perturbation of forebrain principal neurons reveals differential effects in novel and well-learned tasks. - Brain Research
Skeletal Cell YAP And TAZ Redundantly Promote Bone Development By Regulation Of Collagen I Expression And Organization - bioRxiv
Mechanisms Regulating Growth Progression of Salivary Gland Neoplasms Using Mucoepidermoid Carcenoma Primary Cells - Thesis
Dopamine neuron dependent behaviors mediated by glutamate cotransmission - bioRxiv
Measuring the olfactory bulb input-output transformation reveals a contribution to the perception of odorant concentration invariance - Nature Communications
A novel humanized mouse lacking murine P450 oxidoreductase for studying human drug metabolism - Nature Communications
Stabilization of F-actin by tropomyosin isoforms regulates the morphology and mechanical behavior of red blood cells - Molecular Biology of the Cell
Endothelium-derived fibronectin regulates neonatal vascular morphogenesis in an autocrine fashion - Angiogenesis
Monosynaptic retrograde tracing of neurons expressing the G-protein coupled receptor Gpr151 in the mouse brain - The Journal of Comparative Neurology
Tonotopic alterations in inhibitory input to the medial nucleus of the trapezoid body in a mouse model of Fragile X syndrome - The Journal of Comparative Neurology
The Neural Encoding of Reward in the Striatal-Pallidal Circuitry - Thesis
Importance of poly (A)-binding protein 4 (PABP4) in healthy pregnancy - Thesis
Systematic Identification of MCU Modulators by Orthogonal Interspecies Chemical Screening - Molecular Cell
Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance - Nature Communications
Gemcitabine-induced TIMP1 attenuates therapy response and promotes tumor growth and liver metastasis in pancreatic cancer - Cancer Research
The selective Tie2 inhibitor rebastinib blocks recruitment and function of Tie2Hi macrophages in breast cancer and pancreatic neuroendocrine tumors - Molecular Cancer Therapeutics
The Small Rho GTPase TC10 Modulates B Cell Immune Responses - Journal of Immunology
Detection of Maltodextrin and Its Discrimination from Sucrose are Independent of the T1R2+T1R3 Heterodimer - American Journal of Physiology
Increased ethanol drinking in humanized mice expressing the mu opioid receptor A118G polymorphism are mediated through sex-specific mechanisms - Brain Research Bulletin
Mutations in the Katnb1 gene cause left-right asymmetry and heart defects - Developmental Dynamics
Beneficial Effects of Prebiotic Saccharomyces cerevisiae Mannan on Allergic Asthma Mouse Models - Journal of Immunology Research
Morphology of Dbx1 respiratory neurons in the preB̦tzinger complex and reticular formation of neonatal mice - Scientific Data
cTag-PAPERCLIP Reveals Alternative Polyadenylation Promotes Cell-Type Specific Protein Diversity and Shifts Araf Isoforms with Microglia Activation - Neuron
Identification of HSP90 inhibitors as a novel class of senolytics - Nature Communications
Fumarate Hydratase Deletion in Pancreatic β Cells Leads to Progressive Diabetes - Cell Reports
Rubrocerebellar feedback loop isolates the interposed nucleus as an independent processor of corollary discharge information in mice - Journal of Neuroscience
Experience-dependent synaptic plasticity in V1 occurs without microglial CX3CR1 - Journal of Neuroscience
Morphine activation of mu opioid receptors causes disinhibition of neurons in the ventral tegmental area mediated by β-arrestin2 and c-Src - Scientific Reports
Intracellular Chloride Regulation in AVP+ and VIP+ Neurons of the Suprachiasmatic Nucleus - Scientific Reports
Intravenous treatment with human recombinant ApoA-I Milano reduces beta amyloid cerebral deposition in the APP23-transgenic mouse model of Alzheimer's disease - Neurobiology of Aging
Inflammation alters AMPA-stimulated calcium responses in dorsal striatal D2 but not D1 spiny projection neurons - European Journal of Neuroscience
Pazopanib Reduces Phosphorylated Tau Levels and Alters Astrocytes in a Mouse Model of Tauopathy - Journal of Alzheimers Disease
Histone chaperone HIRA deposits histone H3. 3 onto foreign viral DNA and contributes to anti-viral intrinsic immunity - Nucleic Acids Research
Reliable sensory processing in mouse visual cortex through inhibitory interactions between Somatostatin and Parvalbumin interneurons - bioRxiv
Accelerated Systemic Autoimmunity in the Absence of Somatic Hypermutation in 564Igi: A Mouse Model of Systemic Lupus with Knocked-In Heavy and Light Chain Genes - Frontiers in Immunology
Paclitaxel Reduces Axonal Bclw to Initiate IP3R1-Dependent Axon Degeneration. - Neuron
Endothelial jagged-2 sustains hematopoietic stem and progenitor reconstitution after myelosuppression - The Journal of Clinical Investigation‰
Dephosphorylation by protein phosphatase 2A regulates visual pigment regeneration and the dark adaptation of mammalian photoreceptors - Proceedings of the National Academy of Sciences of the United States of America
Molecular architecture underlying fluid absorption by the developing inner ear - Elife
Analysis of Nkx3.1:Cre-driven Erk5 deletion reveals a profound spinal deformity which is linked to increased osteoclast activity - Scientific Reports
Sim1 neurons are sufficient for MC4R-mediated sexual function in male mice - Endocrinology
The caspase-8/RIPK3 signaling axis in antigen presenting cells controls the inflammatory arthritic response - Arthritis Research and Therapy
Characterising the Role of mTORC1 in Myeloid Cells - Thesis
Activation of the Aryl Hydrocarbon Receptor Interferes with Early Embryonic Development - Stem Cell Reports
CXCR2-Dependent Accumulation of Tumor-Associated Neutrophils Regulates T-cell Immunity in Pancreatic Ductal Adenocarcinoma - Cancer Immunology Research
Chronic Stress Alters Striosome-Circuit Dynamics, Leading to Aberrant Decision-Making - Cell
IRF3 and type I interferons fuel a fatal response to myocardial infarction - Nature Medicine
Bim suppresses the development of SLE by limiting myeloid inflammatory responses - Journal of Experimental Medicine
Staphylococcus aureus Epicutaneous Exposure Drives Skin Inflammation via IL-36-Mediated T Cell Responses. - Cell Host Microbe
HIF and HOIL-1L-mediated PKCζ degradation stabilizes plasma membrane Na,K-ATPase to protect against hypoxia-induced lung injury - Proceedings of the National Academy of Sciences of the United States of America
Characterization of ApoJ-reconstituted high-density lipoprotein (rHDL) nanodisc for the potential treatment of cerebral β-amyloidosis - Scientific Reports
In vivo evidence that RBM5 is a tumour suppressor in the lung - Scientific Reports
Accumulation of rest deficiency precedes sudden death of epileptic Kv1.1 knockout mice, a model of sudden unexpected death in epilepsy - Epilepsia
Targeted deletion of c‐Met in thymic epithelial cells leads to an autoimmune phenotype - Immunology and Cell Biology
Brain-derived neurotrophic factor (BDNF) determines a sex difference in cue-conditioned alcohol seeking in rats. - Behavioral Brain Research
Growth Differentiation Factor 11 does not Mitigate the Lethal Effects of Total-Abdominal Irradiation - Radiation Research
Katanin-like 2 (KATNAL2) functions in multiple aspects of haploid male germ cell development in the mouse - PLOS Genetics
Testosterone replacement in transgenic sickle cell mice controls priapic activity and upregulates PDE5 expression and eNOS activity in the penis - Andrology
Mode of Surgical Injury Influences the Source of Urothelial Progenitors during Bladder Defect Repair - Stem Cell Reports
Dose-Dependent Rescue of KO Amelogenin Enamel by Transgenes in Vivo. - Frontiers in Physiology
Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents. - Nature
ERBB3 and NGFR mark a distinct skeletal muscle progenitor cell in human development and hPSCs - Nature Cell Biology
Loss of PBRM1 rescues VHL dependent replication stress to promote renal carcinogenesis - Nature Communications
CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis - Developmental Cell
STING-Dependent Signaling Underlies IL-10 Controlled Inflammatory Colitis - Cell Reports
The STAT3-IL-10-IL-6 Pathway Is a Novel Regulator of Macrophage Efferocytosis and Phenotypic Conversion in Sterile Liver Injury - Journal of Immunology
Kif1bp loss in mice leads to defects in the peripheral and central nervous system and perinatal death - Scientific Reports
Neuronal CCL2 expression drives inflammatory monocyte infiltration into the brain during acute virus infection - Journal of Neuroinflammation
Fatty acid binding protein 5 mediates the uptake of fatty acids, but not drugs, into human brain endothelial cells - Journal of Pharmaceutical Sciences
The Endosomal-Lysosomal Pathway is Dysregulated by APOE4 Expression In Vivo - Frontiers in Neuroscience
HSCB, a Co-chaperone in Mitochondrial Iron-Sulfur Cluster Biogenesis, is a Novel Candidate Gene for Congenital Sideroblastic Anemia - Thesis
Single point mutation on the gene encoding dysbindin results in recognition deficits - Brain and Behavior
Consistent hypersocial behavior in mice carrying a deletion of Gtf2i but no evidence of hyposocial behavior with Gtf2i duplication: Implications for Williams–Beuren syndrome and autism spectrum disorder - Brain and Behavior
Bimodal RMS distributions for the objective detection of theta (θ) and gamma (γ) brain oscillations during long-term continuous LFP recordings in mice - MACRo 2015
Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration - Nature
Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors - Proceedings of the National Academy of Sciences of the United States of America
Targeting multiple effector pathways in pancreatic ductal adenocarcinoma with a G-quadruplex-binding small molecule - Journal of Medicinal Chemistry
Neurogenesis during abstinence is necessary for context-driven methamphetamine-related memory - Journal of Neuroscience
Skeletal cell YAP and TAZ combinatorially promote bone development - The FASEB Journal
Respiratory dysfunction progresses with age in Kcna1-null mice, a model of sudden unexpected death in epilepsy - Epilepsia
Transcriptomic analysis of gene signatures associated with sickle pain - Scientific Data
The large-conductance voltage- and Ca2+ -activated K+ channel and its γ1 subunit modulate mouse uterine artery function during pregnancy - Journal of Physiology (London)
Oxytocin and the warm outer glow: Thermoregulatory deficits cause huddling abnormalities in oxytocin-deficient mouse pups - Hormones and Behavior
Pazopanib Reduces Tau Pathology and Restores Astrocytes in a Novel Mouse Model of Neurodegenerative Tauopathy - Thesis
A Braf kinase-inactive mutant induces lung adenocarcinoma - Nature
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity - Nature Medicine
Delayed Degradation and Impaired Dendritic Delivery of Intron-LackingEGFP-Arc/Arg3.1mRNA inEGFP-ArcTransgenic Mice - Frontiers in Molecular Neuroscience
The Bcl-2 Homology-3 Domain (BH3)-Only Proteins, Bid, DP5/Hrk, and BNip3L, Are Upregulated in Reactive Astrocytes of End-Stage Mutant SOD1 Mouse Spinal Cord - Frontiers in Cellular Neuroscience
The Complement System Is Critical in Maintaining Retinal Integrity during Aging - Frontiers in Aging Neuroscience
Water transport and homeostasis as a major function of erythrocytes - American Journal of Physiology Heart and Circulatory Physiology
Taste sensitivity to a mixture of monosodium glutamate and inosine 5'-monophosphate by mice lacking both subunits of the T1R1+T1R3 amino acid receptor - American Journal of Physiology Regulatory, Integrative and Comparative Physiology
Gain-of-function and dominant-negative effects of distinct p53 mutations in lung tumours - Thesis
Development of T cell based therapeutic strategies for childhood cancer neuroblastoma - Thesis
INSL5 activates multiple signalling pathways and regulates GLP-1 secretion in NCI-H716 cells - Journal of Molecular Endocrinology
Evidence of Wnt/β-Catenin alterations in brain and bone of a tauopathy mouse model of Alzheimer’s disease - Neurobiology of Aging
The vulnerability of spinal motoneurons and soma size plasticity in a mouse model of amyotrophic lateral sclerosis - The Journal of Physiology
Paracrine cellular senescence exacerbates biliary injury and impairs regeneration - Nature Communications
Dopamine D2 Receptors in Dopaminergic Neurons Modulate Performance in a Reversal Learning Task in Mice - eNeuro
Consistent hypersocial behavior in mice carrying a deletion ofGtf2ibut no evidence of hyposocial behavior withGtf2iduplication: Implications for Williams-Beuren syndrome and autism spectrum disorder - Brain and Behavior
Characteristics of cellular and synaptic function in rodent forebrain neurons with altered SynGAP expression - Thesis
Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay - Proceedings of the National Academy of Sciences of the United States of America
Sprouty2 loss-induced IL6 drives castration-resistant prostate cancer through scavenger receptor B1 - EMBO Molecular Medicine
Early long-term administration of the CSF1R inhibitor PLX3397 ablates microglia and reduces accumulation of intraneuronal amyloid, neuritic plaque deposition and pre-fibrillar oligomers in 5XFAD mouse model of Alzheimer's disease - Molecular Neurodegeneration
PI3Kδ hyper-activation promotes the development of B cells that exacerbate Streptococcus pneumoniae infection in an antibody-independent manner - bioRxiv
Phospho-regulation of Atoh1 is required for plasticity of secretory progenitors and tissue regeneration - bioRxiv
Impact of X/Y genes and sex hormones on mouse neuroanatomy - Neuroimage
Extrinsic Phagocyte-Dependent STING Signaling Dictates the Immunogenicity of Dying Cells - Cancer Cell
An Autoimmune Basis for Raynaud's Phenomenon: Murine Model and Human Disease - Arthritis &amp; Rheumatology
Evidence of Wnt/β-catenin alterations in brain and bone of a tauopathy mouse model of Alzheimer's disease - Neurobiology of Aging
Activity-dependent modulation of hippocampal synaptic plasticity via PirB and endocannabinoids - Molecular Psychiatry
Galectins Control mTOR in Response to Endomembrane Damage - Molecular Cell
The ERBB network facilitates KRAS-driven lung tumorigenesis - bioRxiv
SOX11 augments BCR signaling to drive MCL-like tumor development - Blood
The role of CX3CR1 in pancreatic cancer - Thesis
CALHM3 Is Essential for Rapid Ion Channel-Mediated Purinergic Neurotransmission of GPCR-Mediated Tastes - Neuron
Type-2 diabetic aldehyde dehydrogenase 2 mutant mice (ALDH 2*2) exhibiting heart failure with preserved ejection fraction phenotype can be determined by exercise stress echocardiography - PLOS ONE
Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging - Redox Biology
Induction of muscle stem cell quiescence by the secreted niche factor Oncostatin M - Nature Communications
The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia - Cell Metabolism
Studies of Breast Cancer Chemoprevention in Human High-risk Primary Cells and Genetically Engineered Mouse Models - Thesis
Abnormal Sleep Architecture and Hippocampal Circuit Dysfunction in a Mouse Model of Fragile X Syndrome - Neuroscience
CSF1R+ Macrophages Sustain Pancreatic Tumor Growth through T Cell Suppression and Maintenance of Key Gene Programs that Define the Squamous Subtype - Cell Reports
Role of Enteric Glial Activation in Gastrointestinal Physiology and Inflammation - Thesis
Global Untargeted Serum Metabolomic Analyses Nominate Metabolic Pathways Responsive to Loss of Expression of the Orphan Metallo β-Lactamase, Mblac1 - Molecular Omics
MiR-142-3p is downregulated in aggressive p53 mutant mouse models of pancreatic ductal adenocarcinoma by hypermethylation of its locus - Cell Death and Disease
Chemogenetic Enhancement of Axon Regeneration Following Peripheral Nerve Injury in the SLICK-A Mouse - Brain Sciences
Identification of Correlative Shifts in Indices of Brain Cholesterol Metabolism in the C57BL6/Mecp2tm1.1Bird Mouse, a Model for Rett Syndrome - Lipids
Spontaneous Hair Cell Regeneration Is Prevented by Increased Notch Signaling in Supporting Cells - Frontiers in Cellular Neuroscience
Membrane Mucin Muc4 promotes blood cell association with tumor cells and mediates efficient metastasis in a mouse model of breast cancer - Oncogene
Separate functional properties of NMDARs regulate distinct aspects of spatial cognition - Learning &amp; Memory
RNaseT2 knockout rats exhibit hippocampal neuropathology and deficits in memory - Disease Models and Mechanisms
Brown adipose tissue plays a central role in systemic inflammation-induced sleep responses - PLOS ONE
Cell-Type-Specific Role of ΔFosB in Nucleus Accumbens In Modulating Intermale Aggression - The Journal of Neuroscience
A Combination of Ontogeny and CNS Environment Establishes Microglial Identity - Neuron
TectaY1870C/+ mice with alterations in the structure and porosity of the tectorial membrane display large numbers of spontaneous emissions - AIP Conference Proceedings
The Biochemical Effects of Tau and Zinc in A Tau Mouse Model - Thesis
Zinc Exacerbates Tau Pathology in a Tau Mouse Model - Journal of Alzheimers Disease
Effects of living at moderate altitude on pulmonary vascular function and exercise capacity in mice with sickle cell anemia - The Journal of Physiology
Hydroxyurea embryotoxicity is enhanced in P53-deficient mice - Reproductive Toxicology
Functional cross-talk between PTEN and PDK1 in normal haematopoiesis and leukaemia development - Thesis
Investigating the role of thiosulfate sulfurtransferase in adipose tissue dysfunction in obesity - Thesis
A novel sialylation site on Neisseria gonorrhoeae lipooligosaccharide links heptose II lactose expression with pathogenicity - Infection and Immunity
Impairing hepatocyte regeneration to determine the regenerative capacity of the biliary epithelium - Thesis
Iron Chelation with Transdermal Deferoxamine Accelerates Healing of Murine Sickle Cell Ulcers - Advances in Wound Care
POT1a depletion in the developing brain leads to p53-dependent neuronal cell death and ataxia. - bioRxiv
TSPO-PET Imaging Using [18F]PBR06 is a Potential Translatable Biomarker for Treatment Response in Huntington's Disease: Preclinical Evidence with the p75NTR Ligand LM11A-31 - Human Molecular Genetics
Characterization of Adult Vestibular Organs in 11 CreER Mouse Lines - Journal of the Association for Research in Otolaryngology (JARO)
Targeted deletion of c-Met in thymic epithelial cells leads to an autoimmune phenotype - Immunology and Cell Biology
Temporal changes in macrophage phenotype after peripheral nerve injury - Journal of Neuroinflammation
Differential electrophysiological properties of D1 and D2 spiny projection neurons in the mouse nucleus accumbens core - Physiological Reports
Constitutive and Conditional Deletion of Type 1 Dopamine Receptor (Drd1) to Study Food Anticipatory Activity - Thesis
Alterations of functional circuitry in aging brain and the impact of mutated APP expression - Neurobiology of Aging
Triheteromeric GluN1/GluN2A/GluN2C NMDARs with Unique Single-Channel Properties Are the Dominant Receptor Population in Cerebellar Granule Cells - Neuron
Synaptic vesicle recycling in preclinical models of intellectual disability, autism spectrum disorder and epilepsy - Thesis
Tropomyosin 3.5 protects F-actin networks required for tissue biomechanical properties - bioRxiv
Persistent Infiltration and Impaired Response of Peripherally-Derived Monocytes after Traumatic Brain Injury in the Aged Brain - International Journal of Molecular Sciences
Effects of 5-HT1A Receptor Agonism on Repetitive Grooming and Learning Behavior in Shank3B Mice - Thesis
Contractile functions of Piezo1 channels in murine arteries - Thesis
GAL3 receptor knockout mice exhibit an alcohol-preferring phenotype - Addiction Biology
Suppression of Harmaline Tremor by Activation of an Extrasynaptic GABAA Receptor: Implications for Essential Tremor - Tremor and Other Hyperkinetic Movements
Disruption of the Zdhhc9 intellectual disability gene leads to behavioural abnormalities in a mouse model - Experimental Neurology
Citrullinated histone 3 causes endothelial barrier dysfunction - Biochemical and Biophysical Research Communications
53BP1-RIF1-shieldin counteracts DSB resection through CST- and Polα-dependent fill-in - Nature
Loss of maternal EED results in postnatal overgrowth - Clinical Epigenetics
The role of Runx1 in genetic models of breast cancer - Thesis
This is to certify that the work contained within has been composed by me and is entirely my own work. No part of this thesis has been submitted for any other - Thesis
Pathway specific drive of cerebellar Golgi cells reveals integrative rules of cortical inhibition - bioRxiv
Depletion of haptoglobin and hemopexin promote hemoglobin-mediated lipoprotein oxidation in sickle cell disease - American Journal of Physiology
Inhibiting autophagy reduces retinal degeneration caused by protein misfolding - Autophagy
CTCF maintains regulatory homeostasis of cancer pathways - Genome Biology
Astrocytes and neurons produce distinct types of polyglucosan bodies in Lafora disease - Glia
MYBL2 supports DNA double strand break repair in haematopoietic stem cells - Cancer Research
An Examination of the Role of L-Glutamate and Inosine 5'-Monophosphate in Hedonic Taste-Guided Behavior by Mice Lacking the T1R1 + T1R3 Receptor - Chemical Senses
Communication Between Enteric Neurons, Glia, and Nociceptors Underlies the Effects of Tachykinins on Neuroinflammation - Cellular and Molecular Gastroenterology and Hepatology
GPR55 signalling promotes proliferation of pancreatic cancer cells and tumour growth in mice, and its inhibition increases effects of gemcitabine - Oncogene
Intestine-specific expression of human chimeric intestinal alkaline phosphatase attenuates Western diet-induced barrier dysfunction and glucose intolerance - Physiological Reports
Distinct Bone Marrow Sources of Pleiotrophin Control Hematopoietic Stem Cell Maintenance and Regeneration - Stem Cells
Mapping Transgene Insertion Sites Reveals Complex Interactions Between Mouse Transgenes And Neighboring Endogenous Genes - bioRxiv
Neuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for Timely Axon Regeneration - Cell Reports
Exacerbation of dystrophic cardiomyopathy by phospholamban deficiency-mediated chronically increased cardiac Ca2+ cycling in vivo - American Journal of Physiology
Ndr kinases regulate retinal interneuron proliferation and homeostasis - Scientific Reports
One-step CRISPR/Cas9 method for the rapid generation of human antibody heavy chain knock-in mice - The EMBO Journal
Apigenin Inhibits UVB-Induced Skin Carcinogenesis: The Role of Thrombospondin-1 as an Anti-Inflammatory Factor - Neoplasia
Loss of MST/Hippo signaling in a genetically engineered mouse model of fusion-positive rhabdomyosarcoma accelerates tumorigenesis - Cancer Research
A Dominant Role for the Beta 4 Nicotinic Receptor Subunit in Nicotinic Modulation of Glomerular Microcircuits in the Mouse Olfactory Bulb - Journal of Neurophysiology
PI3Kδ hyper-activation promotes development of B cells that exacerbate Streptococcus pneumoniae infection in an antibody-independent manner - Nature Communications
Prestin Contributes to Membrane Compartmentalization and Is Required for Normal Innervation of Outer Hair Cells - Frontiers in Cellular Neuroscience
Fine-Tuning Mybl2 Is Required for Proper Mesenchymal-to-Epithelial Transition during Somatic Reprogramming - Cell Reports
Deficiency of the Endocytic Protein Hip1 Leads to Decreased Gdpd3 expression, Low Phosphocholine, and Kypholordosis - bioRxiv
Knock-in rats expressing Cre and Flp recombinases at the Parvalbumin locus. - bioRxiv
Whole genomes redefine the mutational landscape of pancreatic cancer - Nature
Chronic GLP-1 receptor activation by exendin-4 induces expansion of pancreatic duct glands in rats and accelerates formation of dysplastic lesions and chronic pancreatitis in the Kras(G12D) mouse model - Diabetes
Lhx1 controls terminal differentiation and circadian function of the suprachiasmatic nucleus - Cell Reports
Sialylation regulates brain structure and function - FASEB Journal
Trp63 is regulated by STAT5 in mammary tissue and subject to differentiation in cancer - Endocrine Related Cancer
Beneficial Effect of the Nitric Oxide Donor Compound 3-(1,3-Dioxoisoindolin-2-yl)Benzyl Nitrate on Dysregulated Phosphodiesterase 5, NADPH Oxidase, and Nitrosative Stress in the Sickle Cell Mouse Penis: Implication for Priapism Treatment - Journal of Pharmacology and Expreimental Therapeutics
Sex-specific regulation of weight and puberty by the Lin28/let-7 axis - Journal of Endocrinology
Isoaspartyl formation in creatine kinase B is associated with loss of enzymatic activity; implications for the linkage of isoaspartate accumulation and neurological dysfunction in the PIMT knockout mouse - PLOS ONE
Corrigendum to Enkephalin levels and the number of neuropeptide Y-containing interneurons in the hippocampus are decreased in female cannabinoid-receptor 1 knock-out mice [Neurosci. Lett. 620 (2016) 97-103] - Neuroscience Letters
Investigating the Production of Auto-Antibodies at Different Stages of B Cell Development - Thesis
Targeted lentiviral-mediated delivery of progranulin cDNA in a genetic model of amyotrophic lateral sclerosis - Thesis
Hippocampal neural progenitor cells play a distinct role in fear memory retrieval in male and female CIE rats - Neuropharmacology
Metabolic and vascular effects of thiosulfate sulfurtransferase deletion - Thesis
Ketogenic diet regulates the antioxidant catalase via the transcription factor PPAR?2 - Epilepsy Res.
Examining the Role of Cone-expressed RPE65 in Mouse Cone Function - Sci Rep
Increased tau phosphorylation follows impeded dopamine clearance in a P301L and novel P301L/COMT-deleted (DM) tau mouse model - J. Neurochem.
Inhibition of Atypical Protein Kinase C Reduces Inflammation-Induced Retinal Vascular Permeability - Am. J. Pathol.
Cre-dependent optogenetic transgenic mice without early age-related hearing loss - bioRxiv
Precision medicine approach: Empagliflozin for diabetic cardiomyopathy in mice with aldehyde dehydrogenase (ALDH) 2?2 mutation, a specific genetic mutation in millions of East Asians - Eur. J. Pharmacol.
The EGF-LIKE domain of thrombospondin-4 is a key determinant in the development of pain states due to increased excitatory synaptogenesis - J. Biol. Chem.
GIRK currents in VTA dopamine neurons control the sensitivity of mice to cocaine-induced locomotor sensitization - Proc. Natl. Acad. Sci. U.S.A.
Mouse Models of Pain in Sickle Cell Disease - Curr Protoc Neurosci
Reduced PRC2 function alters male germline epigenetic programming and paternal inheritance - BMC Biol.
Sex differences in vocal communication of freely interacting adult mice depend upon behavioral context - PLOS ONE
The susceptibility of cochlear outer hair cells to cyclodextrin is not related to their electromotile activity - Acta Neuropathol Commun
Astrocyte-Secreted Chordin-like 1 Drives Synapse Maturation and Limits Plasticity by Increasing Synaptic GluA2 AMPA Receptors - Neuron
Impaired innate immune signaling due to combined Toll-like receptor 2 and 4 deficiency affects both periodontitis and atherosclerosis in response to polybacterial infection - Pathog Dis
Estudio de variantes estructurales de ApoA-I y ApoJ recombinantes como aproximación terapéutica en el contexto de la ß-amiloidosis cerebral - Thesis
Sex-Dependent Effects of Environmental Enrichment on Spatial Memory and Brain-Derived Neurotrophic Factor (BDNF) Signaling in a Developmental "Two-Hit" Mouse Model Combining BDNF Haploinsufficiency and Chronic Glucocorticoid Stimulation - Front Behav Neurosci
Loss of amphiregulin reduces myoepithelial cell coverage of mammary ducts and alters breast tumor growth - Breast Cancer Res.
Injury promotes sarcoma development in a genetically and temporally restricted manner - JCI Insight
Investigating the Ca2+-dependent and Ca2+-independent mechanisms for mammalian cone light adaptation - Sci Rep
Genetic and behavioural requirements for structural brain plasticity - bioRxiv
Fisetin is a senotherapeutic that extends health and lifespan - EBioMedicine
Early functional connectivity deficits and progressive microstructural alterations in the TgF344-AD rat model of Alzheimer's Disease: A longitudinal MRI study - Neurobiol. Dis.
NCLX prevents cell death during adrenergic activation of the brown adipose tissue - bioRxiv
Leukemia development initiated by deletion of RBP-J: mouse strain, deletion efficiency, and cell of origin - Dis Model Mech
The HDAC3-SMARCA4-miR-27a axis promotes expression of the PAX3:FOXO1 fusion oncogene in rhabdomyosarcoma - Sci Signal
Placental Macrophages: A Window Into Fetal Microglial Function in Maternal Obesity - Int. J. Dev. Neurosci.
Early impacts of modified food consistency on oromotor outcomes in mouse models of Down syndrome - Physiol. Behav.
Macrophage Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer - bioRxiv
Diet-Induced Insulin Resistance Elevates Hippocampal Glutamate as well as VGLUT1 and GFAP Expression in AßPP/PS1 Mice - J. Neurochem.
NLRP3 Promotes Diabetic Bladder Dysfunction and Changes in Symptom-Specific Bladder Innervation - Diabetes
Foxc2 is required for proper cardiac neural crest cell migration, outflow tract septation, and ventricle expansion - Dev. Dyn.
Direct intracellular signaling by the carboxy terminus of NMDA receptor GluN2 subunits regulates dendritic morphology in hippocampal CA1 pyramidal neurons - Neuroscience
Investigating the Role of the Growth Hormone Secretagogue Receptor in Food-Motivated Behaviours - Thesis
Increased susceptibility to cortical spreading depression and epileptiform activity in a mouse model for FHM2 - Sci Rep
Establishing sleep stages using Delta, Theta and Gamma oscillations from long term Local Field Potential (LFP) recordings in mice - researchgate.net
Knock-in rat lines with Cre recombinase at the dopamine D1 and adenosine 2a receptor loci. - bioRxiv
Phenotypic Modulation of Skeletal Muscle Fibers in LPIN1-Deficient Lipodystrophic ( fld) Mice - Vet. Pathol.
CHARACTERIZING AQP9: A REGULATOR OF EPIPHYSEAL PLATE CHONDROCYTE PROLIFERATION, HYPERTROPHY, AND LONG BONE GROWTH - Thesis
1-(4-nitrobenzenesulfonyl)-4-penylpiperazine increases the number of Peyer’s patch-associated regenerating crypts in the small intestines after radiation injury - Radiotherapy and Oncology
Improving Outcomes in NF1 Spine Fusion - Thesis
Arkadia degrades SNON to activate level-specific NODAL responses - bioRxiv
Salmonella Persist in Activated Macrophages in T Cell-Sparse Granulomas but Are Contained by Surrounding CXCR3 Ligand-Positioned Th1 Cells - Immunity
Multiple receptors converge on H2-Q10 to regulate NK &amp; γδT cell development - Immunology and Cell Biology
Early Life Stress Drives Sex-Selective Impairment in Reversal Learning by Affecting Parvalbumin Interneurons in Orbitofrontal Cortex of Mice - Cell Rep
Sox9 regulates cell state and activity of embryonic mouse mammary progenitor cells - Communications Biology
A Novel hAPP/htau Mouse Model of Alzheimer's Disease: Inclusion of APP With Tau Exacerbates Behavioral Deficits and Zinc Administration Heightens Tangle Pathology - Front Aging Neuroscience
Sex- and Development-Dependent Responses of Rat Microglia to Pro- and Anti-inflammatory Stimulation - Front Cell Neuroscience
The Effect of Maternal Obesity on Placental Cell-Free DNA Release in a Mouse Model - Reproductive Sciences
Sudden heart rate reduction upon optogenetic release of acetylcholine from cardiac parasympathetic neurons in perfused hearts - bioRxiv
A sensorimotor pathway via higher-order thalamus - Journal of Neuroscience
Harnessing Genetic Complexity to Enhance Translatability of Alzheimer's Disease Mouse Models: A Path toward Precision Medicine - Neuron
The α7 nicotinic acetylcholine receptors regulate hippocampal adult-neurogenesis in a sexually dimorphic fashion - Brain Structure and Function
Cellular interactions underpinning the immunomodulatory action of mesenchymal stromal cells in models of liver transplant injury - Thesis
LCAT Enzyme Replacement Therapy Reduces LpX and Improves Kidney Function in a Mouse Model of Familial LCAT Deficiency - Journal of Pharmacology and Experimental Therapeutics
SETD3 is an actin histidine methyltransferase that prevents primary dystocia - Nature
KLF9-dependent ROS regulate melanoma progression in stage-specific manner - Oncogene
NF-kB signaling in myeloid cells mediates the pathogenesis of immune-mediated nephritis - Journal of Autoimmunity
Spontaneous Otoacoustic Emissions in TectaY1870C/+ Mice Reflect Changes in Cochlear Amplification and How It Is Controlled by the Tectorial Membrane - eNeuro
Repetitive mild concussion in subjects with a vulnerable cholinergic system: lasting cholinergic-attentional impairments in CHT+/-mice. - bioRxiv
Missense Mutations in the Human Nanophthalmos Gene TMEM98 Cause Retinal Defects in the Mouse - bioRxiv
Nucleus accumbens Drd1-expressing neurons control aggression self-administration and aggression seeking in mice - Journal of Neuroscience
Atypical Auditory Brainstem Response and Protein Expression Aberrations Related to ASD and Hearing Loss in the Adnp Haploinsufficient Mouse Brain - Neurochemical Research
Cervix Stromal Cells and the Progesterone Receptor A Isoform Mediate Effects of Progesterone for Prepartum Remodeling - Reproductive Sciences
Chemotaxis in Pacreatic Ductal Adenocarcinoma Metastasis: An Unexpected Role of NWASP in Maintaining Self-Generated Gradients and LPA Receptor Recycling - Cell Press
Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models - Nature Cell Biology
Lentiviral Gene Therapy in HSCs Restores Lineage-Specific Foxp3 Expression and Suppresses Autoimmunity in a Mouse Model of IPEX Syndrome - Cell Stem Cell
Aquaporin-4-dependent glymphatic solute transport in the rodent brain - Elife
Disruption of the Interaction of RAS with PI 3-Kinase Induces Regression of EGFR-Mutant-Driven Lung Cancer - Cell Reports
High-molecular-weight polymers from dietary fiber drive aggregation of particulates in the murine small intestine - Elife
Sexually Dimorphic Vasopressin Cells Modulate Social Investigation and Communication in Sex-Specific Ways - eNeuro
The Lin28/let-7 Pathway Regulates the Mammalian Caudal Body Axis Elongation Program - Developmental Cell
NCOA4 maintains murine erythropoiesis via cell autonomous and non-autonomous mechanisms - Haematologica
T1R2+T1R3-independent Chemosensory Inputs Contributing to Behavioral Discrimination of Sugars in Mice - American Journal of Physiology - Regulatory, Integrative and Comparative Physiology
Sex-Specific Proteomic Changes Induced by Genetic Deletion of Fibroblast Growth Factor 14 (FGF14), a Regulator of Neuronal Ion Channels - Proteomes
The autism/neuroprotection-linked ADNP/NAP regulate the excitatory glutamatergic synapse - Translational Psychiatry
Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis - Nature Communications
Sex Differences in Nociceptin/Orphanin FQ Peptide Receptor-Mediated Pain and Anxiety Symptoms in a Preclinical Model of Post-traumatic Stress Disorder - Frontiers in Psychiatry
Tfh Lymphoma: Analysis of a RHOA Mutation & Establishment of a Pre-Clinical Model - Thesis
Pomalidomide alters pancreatic macrophage populations to generate an immune-responsive environment at precancerous and cancerous lesions - Cancer Research
Measuring biological age in mice using differential mass spectrometry - Aging
1-(4-nitrobenzenesulfonyl)-4-penylpiperazine increases the number of Peyer's patch-associated regenerating crypts in the small intestines after radiation injury - Radiotherapy and Oncology
An orthogonal c-Cbl recognition mode targets LynA for rapid degradation and builds specificity into the LynA checkpoint - bioRxiv
P128 INHIBITION OF INTESTINAL EPITHELIAL CELL PYROPTOSIS AND ASSOCIATED MUCOSAL BARRIER DEFECTS IS A POTENTIAL THERAPEUTIC MECHANISM OF ACTION FOR MESALAMINE IN IBD - Inflammatory Bowel Diseases
22 kHz and 55 kHz ultrasonic vocalizations differentially influence neural and behavioral outcomes: Implications for modeling anxiety via auditory stimuli in the rat - Behavioural Brain Research
Effects of the dual orexin receptor antagonist DORA-22 on sleep in 5XFAD mice - Alzheimer's & Dementia: Translational Research & Clinical Interventions
Chemokine Receptor Redundancy and Specificity Are Context Dependent - Immunity
Fish Oil Protects the Liver from Parenteral Nutrition-induced Injury via GPR120-mediated PPARγ signaling - Prostaglandins, Leukotrienes and Essential Fatty Acids
Estrogen receptor-alpha knockouts and maternal memory in nulliparous rats - Hormones and Behavior
IPMK Mediates Activation of ULK Signaling and Transcriptional Regulation of Autophagy Linked to Liver Inflammation and Regeneration - Cell Reports
Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer - Cell Metabolism
Brain distribution of a panel of EGFR inhibitors using cassette-dosing in wild-type and Abcb1/Abcg2 deficient mice - Drug Metabolism and Disposition
The Tug1 Locus is Essential for Male Fertility - bioRxiv
CRISP2 is a regulator of multiple aspects of sperm function and male fertility - Endocrinology
Interneuron functional diversity in the mouse accessory olfactory bulb - bioRxiv
Multiple supporting cell subtypes are capable of spontaneous hair cell regeneration in the neonatal mouse cochlea - Development
Tissue curvature and apicobasal mechanical tension imbalance instruct cancer morphogenesis - Nature
Oxytocin Neurons Enable Melanocortin Regulation of Male Sexual Function in Mice - Molecular Neurobiology
The Alteration of Intrinsic Excitability and Synaptic Transmission in Lumbar Spinal Motor Neurons and Interneurons of Severe Spinal Muscular Atrophy Mice - Frontiers in Cellular Neuroscience
Stage-dependent differential effects of interleukin-1 isoforms on experimental atherosclerosis - European Heart Journal
Development of hair cell phenotype and calyx nerve terminals in the neonatal mouse utricle - Journal of Comparative Neurology
CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis - Cancer Cell
LSO: Ce Inorganic Scintillators are Biocompatible with Neuronal and Circuit Function - bioRxiv
Intrinsic cell-penetrating activity propels Omomyc from proof of concept to viable anti-MYC therapy - Science Translational Medicine
A simple genotyping method to detect small CRISPR-Cas9 induced indels by agarose gel electrophoresis - Scientific Reports
Parental obesity programs pancreatic cancer development in offspring - Endocrine-Related Cancer
Chronic otitis media is initiated by a bulla cavitation defect in the FBXO11 mouse model - Disease Models and Mechanisms
Effect of adolescent androgen manipulation on psychosis-like behaviour in adulthood in BDNF heterozygous and control mice - Hormones and Behavior
Sex-Specific Involvement of Estrogen Receptors in Behavioral Responses to Stress and Psychomotor Activation - Fronters in Psychiatry
Septal GABA and Glutamate Neurons Express RXFP3 mRNA and Depletion of Septal RXFP3 Impaired Spatial Search Strategy and Long-Term Reference Memory in Adult Mice - Frontiers in Neuroanatomy
LY379268 Does Not Have Long-Term Procognitive Effects nor Attenuate Glutamatergic Signaling in AβPP/PS1 Mice - Journal of Alzheimer's Disease
Brf1 loss and not overexpression disrupts tissues homeostasis in the intestine, liver and pancreas - Cell Death and Differentiation
Cre-Dependent Optogenetic Transgenic Mice Without Early Age-Related Hearing Loss - Frontiers in Aging Neuroscience
P127 THE TRANS-GOLGI NETWORK PROTEIN AFTIPHILIN REGULATES COLONIC EPITHELIAL CELL MIGRATION AND IS CRUCIAL TO EMBRYONIC DEVELOPMENT - Gastroenterology
Ablating astrocyte insulin receptors leads to delayed puberty and hypogonadism in mice - PLoS Biology
Growth and excitability at synapsin II deficient hippocampal neurons - Molecular and Cellular Neuroscience
Mast Cells Induce Blood Brain Barrier Damage in SCD by Causing Endoplasmic Reticulum Stress in the Endothelium - Frontiers in Cellular Neuroscience
Endothelial Adora2a activation promotes blood-brain barrier breakdown and cognitive impairment in mice with diet-induced insulin resistance - Journal of Neuroscience
A role for Hypoxia Inducible Factor 1a (HIF1a) in intermittent hypoxia-dependent changes in spatial memory and synaptic plasticity - bioRxiv
Omega-3 fatty acids are protective in hepatic ischemia reperfusion injury in the absence of GPR120 signaling - Journal of Pediatric Surgery
Complete Regression of Advanced Pancreatic Ductal Adenocarcinomas upon Combined Inhibition of EGFR and C-RAF - Cancer Cell
Inhibition of Lipin lipid phosphatase hyperactivity rescues TorsinA neurological disease - bioRxiv
N-terminal syndecan-2 domain selectively enhances 6-O heparan sulfate chains sulfation and promotes VEGFA165-dependent neovascularization - Nature Communications
Uniquely human CHRFAM7A gene increases the hematopoietic stem cell reservoir in mice and amplifies their inflammatory response - Proceedings of the National Academy of Sciences of U.S.A.
Role of ectodysplasin signalling in middle ear and nasal pathology in rat and mouse models of hypohidrotic ectodermal dysplasia - Disease Models & Mechanisms
Novel mechanisms of Atg16L1 recruitment in non-canonical autophagy - Thesis
Osteocytes remodel bone by TGF-β-induced YAP/TAZ signaling - bioRxiv
Establishment of an Animal Model of Depression: The Serotonin Transporter Knockout Rat - Thesis
Subtle differences in synaptic transmission in medial nucleus of trapezoid body neurons between wild-type and Fmr1 knockout mice - Brain Research
Cardiomyocyte glucocorticoid and mineralocorticoid receptors directly and antagonistically regulate heart disease in mice - Science Signaling
MyD88 and IL-1R signaling drive antibacterial immunity and osteoclast-driven bone loss during Staphylococcus aureus osteomyelitis - PLoS Pathogens
Silibinin inhibits ultraviolet B radiation-induced mast cells recruitment and bone morphogenetic protein 2 expression in the skin at early stages in Ptch(+/-) mouse model of basal cell carcinoma - Molecular Carcinogenesis
Haploinsufficiency of the brain-derived neurotrophic factor gene is associated with reduced pain sensitivity - Pain
A new immunotherapeutic concept for pancreatic cancer using childhood vaccine recall antigens and Listeria - bioRxiv
A DNMT3A PWWP mutation leads to methylation of bivalent chromatin and growth retardation in mice - Nature Communications
A role for Hypoxia Inducible Factor 1a (HIF1a) in intermittent hypoxia-dependent changes to spatial memory and synaptic plasticity - bioRxiv
Whole body glucoregulation and tissue-specific glucose uptake in a novel Akt substrate of 160 kDa knockout rat model - PLOS ONE
Dynamic Network Activation of Hypothalamic MCH Neurons in REM Sleep and Exploratory Behavior - Journal of Neuroscience
Combined loss of GLP-1R and Y2R does not alter progression of high-fat diet-induced obesity or response to RYGB surgery in mice - Molecular Metabolism
Quantifying Microsatellite Mutation Rates from Intestinal Stem Cell Dynamics in Msh2-deficient Murine Epithelium - Genetics
Uterine Gαq/11 signaling, in a progesterone-dependent manner, critically regulates the acquisition of uterine receptivity in the female mouse - FASEB Journal
Peripheral administration of human recombinant ApoJ/clusterin modulates brain beta-amyloid levels in APP23 mice - Alzheimers Research and Therapy
A distal super enhancer mediates estrogen-dependent mouse uterine-specific gene transcription of Insulin-like growth factor 1 (Igf1) - Journal of Biological Chemistry
Spontaneous and Acetylcholine Evoked Calcium Transients in the Developing Mouse Utricle - Frontiers in Cellular Neuroscience
Mo1101 – Superior Mesenteric Vein Occlusion in Rats Induced Portal and Caval Hypertension, Aortic Hypotension, and Peaked P Waves, Tachycardia. Therapy with Pentadecapeptide Bpc 157. Bypassing Pathway to Circumvent Venous Occlusion - Gastroenterology
Genetic reduction of MMP-9 in the Fmr1 KO mouse partially rescues prepulse inhibition of acoustic startle response - Brain Research
Importance of the conserved carboxyl-terminal CNOT1 binding domain to tristetraprolin (TTP) activity in vivo - Molecular and Cellular Biology
The Firre locus produces a trans-acting RNA molecule that functions in hematopoiesis - bioRxiv
Chemopreventive efficacy of oral curcumin: a prodrug hypothesis - FASEB Journal
JNK1/2 represses Lkb1-deficiency-induced lung squamous cell carcinoma progression - Nature Communications
Auditory binaural and spatial hearing impairments in a Fragile X Syndrome mouse model - bioRxiv
Atypical complement receptor C5aR2 transports C5a to initiate neutrophil adhesion and inflammation - Science Immunology
Deletion of p38α MAPK in microglia blunts trauma-induced inflammatory responses in mice - Journal of Neuroinflammation
On the Legacy of Genetically Altered Mouse Models to Explore Vestibular Function: Distribution of Vestibular Hair Cell Phenotypes in the Otoferlin-Null Mouse - Annals of Otology, Rhinology and Laryngology
Deletion of exons 17 and 18 in prestin's STAS domain results in loss of function - Scientific Reports
Effect of ovariectomy on the progression of chronic kidney disease-mineral bone disorder (CKD-MBD) in female Cy/+ rats - Scientific Reports
Excessive ROS inhibits IL-17A&lt;sup&gt;+&lt;/sup&gt; γδ T cells and innate cellular responses to bacterial lung infection - Antioxidants and Redox Signaling
Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles - Cell Reports
Regulatory T cells shape the CD4 T cell response to Salmonella - Thesis
Effective delivery of a microtubule polymerization inhibitor synergizes with standard regimens in models of pancreatic ductal adenocarcinoma - Clinical Cancer Research
Sexual dimorphism in fear learning memory due to epigenetic modification by Cdk5 - Conference
Tetrodotoxin-sensitive sodium channels mediate action potential firing and excitability in menthol-sensitive Vglut3-lineage sensory neurons - bioRxiv
NTPDase1 and -2 are expressed by distinct cellular compartments in the mouse colon and differentially impact colonic physiology and function after DSS-colitis - American Journal of Physiology - Gastrointestinal and Liver Physiology
The Peripheral Nervous System: From Molecular Mechanisms to Non-Invasive Therapeutics - Thesis
Urinary dysfunction in transgenic sickle cell mice: model of idiopathic overactive bladder syndrome - American Journal of Physiology-Renal Physiology
Spaced training improves learning in Ts65Dn and Ube3a mouse models of intellectual disabilities - Translational Psychiatry
RAC1P29S Induces a Mesenchymal Phenotypic Switch via Serum Response Factor to Promote Melanoma Development and Therapy Resistance - Cancer Cell
ERBB2 Regulates MED24 during Cancer Progression in Mice with Pten and Smad4 Deletion in the Pulmonary Epithelium - Cells
Identification of a Clinically Relevant Signature for Early Progression in KRAS-Driven Lung Adenocarcinoma - Cancers (Basel)
Genetic background modifies CNS-mediated sensorimotor decline in the AD-BXD mouse population - bioRxiv
Development of mouse models of angiosarcoma driven by p53 - Disease Models and Mechanisms
A Discrete Dorsal Raphe to Basal Amygdala 5-HT Circuit Calibrates Aversive Memory - Neuron
Altered ocular parameters from circadian clock gene disruptions - PLOS ONE
Sleep and body temperature in TNFα knockout mice: the effects of sleep deprivation, β3-AR stimulation and exogenous TNFα - Brain, Behavior, and Immunity
Mo1106 – Immunologic Dissection of Colitis Related to Checkpoint Inhibitor Immunotherapy - Gastroenterology
Epigenetic Compensation Promotes Liver Regeneration - Developmental Cell
Why flavored vape products may be attractive: Green apple tobacco flavor elicits reward-related behavior, upregulates nAChRs on VTA dopamine neurons, and alters midbrain dopamine and GABA neuron function - Neuropharmacology
Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells - Elife
Gaboxadol Normalizes Behavioral Abnormalities in a Mouse Model of Fragile X Syndrome - Frontiers in Behavioral Neuroscience
Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy - Cell
RDH10 function is necessary for spontaneous fetal mouth movement that facilitates palate shelf elevation - Disease Models and Mechanisms
mTORC1 to AMPK switching underlies β-cell metabolic plasticity during maturation and diabetes - Journal of Clinical Investigation
Mouse Ovarian Cancer Models Recapitulate the Human Tumor Microenvironment and Patient Response to Treatment - SSRN Journal
Anchoring of intratumorally administered cytokines to collagen safely potentiates systemic cancer immunotherapy - Science Translational Medicine
Interleukin-1 receptor accessory proteins are required for normal homeostatic responses to sleep deprivation - Journal of Applied Physiology
Notch Signaling Controls Ciliary Body Morphogenesis and Secretion by Directly Regulating Nectin Protein Expression - SSRN Journal
Loss of Function of Phosphodiesterase 11A4 Shows that Recent and Remote Long-Term Memories Can Be Uncoupled - Current Biology
Localization of amyloid beta peptides to locus coeruleus and medial prefrontal cortex in corticotropin releasing factor overexpressing male and female mice - Brain Structure and Function
Characterisation of the Fibrinogen RGD Sequence in Erythrocyte Binding and Clot Structure - Thesis
Inhibition of neutral sphingomyelinase-2 facilitates remyelination - bioRxiv
Fibroblast-specific deletion of interleukin-1 receptor-1 reduces adverse cardiac remodeling following myocardial infarction - JCI Insight
Piezo1 channel activates ADAM10 sheddase to regulate Notch1 and gene expression - bioRxiv
Ciliary phosphatidylinositol phosphatase Inpp5e plays positive and negative regulatory roles in Shh signaling - bioRxiv
Akt3-Mediated Protection Against Inflammatory Demyelinating Disease - Frontiers in Immunology
Defects in fetal mouth movement and pharyngeal patterning underlie cleft palate caused by retinoid deficiency. - Thesis
Defects in the Exocyst-Cilia Machinery Cause Bicuspid Aortic Valve Disease and Aortic Stenosis - Circulation
An MRI-Derived Neuroanatomical Atlas of the Fischer 344 Rat Brain for Automated Anatomical Segmentation - bioRxiv
Characterization of the Von Willebrand Domain-Containing Protein 8 (Vwa8) Gene in Mouse - Thesis
Dietary inulin alters the gut microbiome, enhances systemic metabolism and reduces neuroinflammation in an APOE4 mouse model - PLOS ONE
Mechanotransduction-dependent control of stereocilia dimensions and row identity in inner hair cells - bioRxiv
Absolute measurement of the tissue origins of cell-free DNA in the healthy state and following paracetamol overdose - bioRxiv
Autoimmune-mediated retinopathy in CXCR5-deficient mice as the result of accumulation of age-related macular degeneration associated proteins - Frontiers in Immunology
Sarm1 deletion reduces axon damage, demyelination, and white matter atrophy after experimental traumatic brain injury - Experimental Neurology
Gene Therapy Correction of Aldehyde Dehydrogenase 2 Deficiency - Molecular Therapy - Methods & Clinical Development
Driving Neuronal Differentiation through Reversal of an ERK1/2-miR-124-SOX9 Axis Abrogates Glioblastoma Aggressiveness - Cell Reports
Post-Transcriptional Bone Morphogenetic Protein 2 (BMP2) Gene Regulation in Aorta - bioRxiv
Using Genetically Encoded Voltage Indicators (GEVIs) to Study the Input-Output Transformation of the Mammalian Olfactory Bulb - Frontiers in Cellular Neuroscience
Activity dynamics of amygdala GABAergic neurons during cataplexy of narcolepsy - Elife
Pathway-Specific Drive of Cerebellar Golgi Cells Reveals Integrative Rules of Cortical Inhibition - Journal of Neuroscience
Retrograde neurotensin release from dopamine neurons drives long-term depression of substantia nigra dopamine signaling - bioRxiv
Sex-specific hippocampal metabolic signatures at the onset of systemic inflammation with lipopolysaccharide in the APPswe/PS1dE9 mouse model of Alzheimer\'s disease - Brain, Behavior, and Immunity
LSO:Ce Inorganic Scintillators Are Biocompatible With Neuronal and Circuit Function - Frontiers in Synaptic Neuroscience
Visual Discrimination, Serial Reversal, and Extinction Learning in the mdx Mouse - Frontiers in Behavioral Nueroscience
Enterovirus pathogenesis requires the host methyltransferase SETD3 - Nature Microbiology
Myosin-II mediated traction forces evoke localized Piezo1-dependent Ca 2+ flickers - Communications Biology
ATMIN is a tumor suppressor gene in lung adenocarcinoma - Cancer Research
The Role of the Direct and Indirect Basal Ganglia Pathways in the Learning, Performance, and Goal-Directed Control of Action Sequences - Thesis
The Adult Ts65Dn Mouse Model of Down Syndrome Shows Altered Swallow Function - Frontiers in Neuroscience
Non-invasive in vivo hyperspectral imaging of the retina for potential biomarker use in Alzheimer\'s disease - Nature Communications
Suppression of HIF2 signalling attenuates the initiation of hypoxia-induced pulmonary hypertension - European Respiratory Journal
Targeting the metabolic response to statin-mediated oxidative stress produces a synergistic anti-tumor response - Cancer Research
Manganese transporter Slc30a10 controls physiological manganese excretion and toxicity - Journal of Clinical Investigation
Genetic ablation of neural progenitor cells impairs acquisition of trace eyeblink conditioning - eNeuro
A Successful 14th felasa congress! - Laboratory Animals
Genetic background modifies CNS‐mediated sensorimotor decline in the AD‐BXD mouse model of genetic diversity in Alzheimer's disease - Genes, Brain and Behavior
A FAM83A Positive Feed-back Loop Drives Survival and Tumorigenicity of Pancreatic Ductal Adenocarcinomas - Scientific Reports
Pulmonary neutrophilia caused by absence of the NF-κB member RelB is dampened by exposure to cigarette smoke - Molecular Immunology
Disruption of type III interferon genes Ifnl2 and Ifnl3 recapitulates loss of the type III IFN receptor in the mucosal antiviral response - Journal of Virology
Acute Microglial Responses to Single Non-Epileptogenic vs. Epileptogenic Seizures in Mouse Hippocampus - Thesis
Reversal of Cognitive Impairment in gp120 Transgenic Mice by the Removal of the p75 Neurotrophin Receptor - Frontiers in Cellular Neuroscience
The autism-mutated ADNP plays a key role in stress response - Translational Psychiatry
Age-dependent hippocampal network dysfuntion in a mouse model of alpha-synucleinopathy - Thesis
Sexually dimorphic role of BNST vasopressin cells in sickness and social behavior in male and female mice - Brain, Behavior, and Immunity
Mo1102 – Aspirin and Ischemia in the Murine Distal Colon - Gastroenterology
A Mechanism Linking Two Known Vulnerability Factors for Alcohol Abuse: Heightened Alcohol Stimulation and Low Striatal Dopamine D2 Receptors - Cell Rep
The Balance between Prostaglandin E2 EP3 and EP4 Receptors Determines Severity of Cardiac Damage in Myocardial Infarction and an Angiotensin II-Induced Model of Hypertension - Thesis
FRS2α-dependent cell fate transition during endocardial cushion morphogenesis - Developmental Biology
Stress-Induced Cellular Clearance Is Mediated by the SNARE Protein ykt6 and Disrupted by α-Synuclein - Neuron
Avian erythroblastosis virus E26 oncogene homolog-1 (ETS-1) plays a role in renal microvascular pathophysiology in the Dahl salt-sensitive rat - Kidney International
Chemogenetic inhibition in the dorsal striatum reveals regional specificity of direct and indirect pathway control of action sequencing - bioRxiv
Mo1103 – Restrictive Expression of Metalloendopeptidase Adam-Like Decysin 1 (ADAMDEC1) in Colonic Subepithelial Pdgfrα+ Cells is a New Marker for Intestinal Bowel Disease - Gastroenterology
YAP and TAZ Mediate Osteocyte Perilacunar/Canalicular Remodeling - Journal of Bone and Mineral Research
Mo1104 – The Trans-Golgi Network Protein Aftiphilin Regulates Colonic Epithelial Cell Migration and is Crucial to Embryonic Development - Gastroenterology
The novel glutamine antagonist prodrug JHU395 has antitumor activity in malignant peripheral nerve sheath tumor - Molecular Cancer Therapeutics
Heterogeneous Cellular Contributions to Elastic Laminae Formation in Arterial Wall Development - Circulation Research
RNase L Antiviral Activity Is Not a Critical Component of the Oas1b-Mediated Flavivirus Resistance Phenotype - Journal of Virology
A sex difference in the composition of the rodent postsynaptic density - bioRxiv
Systemic AAV8-mediated delivery of a functional copy of muscle glycogen phosphorylase (Pygm) ameliorates disease in a murine model of McArdle disease - Human Molecular Genetics
Sudden Heart Rate Reduction Upon Optogenetic Release of Acetylcholine From Cardiac Parasympathetic Neurons in Perfused Hearts - Frontiers in Physiology
Dysregulated NO/PDE5 signaling in the sickle cell mouse lower urinary tract: Reversal by oral nitrate therapy - Life Sciences
Knock-In Rat Lines with Cre Recombinase at the Dopamine D1 and Adenosine 2a Receptor Loci - eNeuro
CBE1 Is a Manchette- and Mitochondria-Associated Protein With a Potential Role in Somatic Cell Proliferation - Endocrinology
Pre-plaque Aß-Mediated Impairment of Synaptic Depotentiation in a Transgenic Rat Model of Alzheimer\'s Disease Amyloidosis - Frontiers in Neuroscience
Sphingomyelinase disables Piezo1 channel inactivation to enable sustained response to mechanical force - bioRxiv
Segmented Filamentous Bacteria Prevent and Cure Rotavirus Infection - Cell
Effects of Sexual Experience and Puberty on Mouse Genital Cortex revealed by Chronic Imaging - Current Biology
Microbiota of MR1 deficient mice confer resistance against Clostridium difficile infection - PLOS ONE
Deletion of the microRNA-degrading nuclease, translin/trax, prevents pathogenic vascular stiffness - American Journal of Physiology-Heart and Circulatory Physiology
Dual and Opposing Functions of the Central Amygdala in the Modulation of Pain - Cell Rep
Mice with Large Deletions of Tyrosine Hydroxylase in Dopamine Neurons No Longer Predict Scheduled Meal Time on Circadian Time Scales - Thesis
Siglec-8 antibody reduces eosinophils and mast cells in a transgenic mouse model of eosinophilic gastroenteritis - JCI Insight
Opposing peripheral fates of tissue-restricted self antigen-specific conventional and regulatory CD4+ T cells - European Journal of Immunology
Age-related changes in eye lens biomechanics, morphology, refractive index and transparency - Aging (Albany NY)
Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice - Aging Cell
The effects of the inactivation of Hydroxyproline dehydrogenase on urinary oxalate and glycolate excretion in mouse models of primary hyperoxaluria - Biochim Biophys Acta Mol Basis Dis
Inhibitory regulation of calcium transients in prefrontal dendritic spines is compromised by a nonsense Shank3 mutation - bioRxiv
Type I interferon responses to ischemic injury begin in the bone marrow of mice and humans and depend on Tet2, Nrf2, and Irf3 - bioRxiv
The nanophthalmos protein TMEM98 inhibits MYRF self-cleavage and is required for eye size specification - bioRxiv
Age-related macular degeneration-like phenotypic features develop at the early ages of Cxcr5/Nrf2 double knockout mice: An accelerated AMD model - bioRxiv
Regulation of heterotopic ossification through local inflammatory monocytes in a mouse model of aberrant wound healing - bioRxiv
Tumor-targeted delivery of childhood vaccine recall antigens by attenuated Listeria reduces pancreatic cancer - bioRxiv
Galectin-3 Coordinates a Cellular System for Lysosomal Repair and Removal - Dev. Cell
Cell-type-specific regulation of neuronal intrinsic excitability by macroautophagy - Elife
A sex difference in the response of the rodent postsynaptic density to synGAP haploinsufficiency - Elife
Cannabinoid signaling recruits astrocytes to modulate presynaptic function in the Suprachiasmatic Nucleus - eNeuro
Characterization of auditory and binaural spatial hearing in a Fragile X Syndrome mouse model - eNeuro
Neuronal ablation of mt-AspRS in mice induces immune pathway activation prior to severe and progressive cortical and behavioral disruption - Exp. Neurol.
VIP/PACAP-Based Drug Development: The ADNP/NAP-Derived Mirror Peptides SKIP and D-SKIP Exhibit Distinctive in vivo and in silico Effects - Front Cell Neurosci
Decoupling the Effects of the Amyloid Precursor Protein From Amyloid-β Plaques on Axonal Transport Dynamics in the Living Brain - Front Cell Neurosci
Generation of a ChATCre mouse line without the early onset hearing loss typical of the C57BL/6J strain - Hear. Res.
Type I interferon responses to ischemic injury begin in the bone marrow of - Heart
Systemic AAV-mediated Gene Therapy Prevents the Multi-organ Disorders Associated with Aldehyde Dehydrogenase 2 Deficiency and Chronic Ethanol Ingestion - Hum. Gene Ther.
Through Reducing ROS Production, IL-10 Suppresses Caspase-1-Dependent IL-1β Maturation, thereby Preventing Chronic Neuroinflammation and Neurodegeneration - Int J Mol Sci
Monocyte-Derived Macrophages Are Necessary for Beta-Adrenergic Receptor-Driven Choroidal Neovascularization Inhibition - Invest. Ophthalmol. Vis. Sci.
Electrophysiological responses to sugars and amino acids in the nucleus of the solitary tract of type 1 taste receptor double knockout mice - J. Neurophysiol.
Sex-specific differences in endoplasmic reticulum aminopeptidase 1 modulation influence blood pressure and renin-angiotensin system responses - JCI Insight
CD93 is expressed on chronic myeloid leukemia stem cells and identifies a quiescent population which persists after tyrosine kinase inhibitor therapy - Leukemia
AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System - Mol. Cell
Retinoic acid degradation shapes zonal development of vestibular organs and sensitivity to transient linear accelerations - Nat Commun
Non-canonical Wnt signalling regulates scarring in biliary disease via the planar cell polarity receptors - Nat Commun
Molecular determinants of nephron vascular specialization in the kidney - Nat Commun
Wireless, battery-free, fully implantable multimodal and multisite pacemakers for applications in small animal models - Nat Commun
Dysregulation of Rac or Rho elicits death of motor neurons and activation of these GTPases is altered in the G93A mutant hSOD1 mouse model of amyotrophic lateral sclerosis - Neurobiol. Dis.
Branched Photoswitchable Tethered Ligands Enable Ultra-efficient Optical Control and Detection of G Protein-Coupled Receptors In Vivo - Neuron
The role of the estrogen receptor-α gene, Esr1, in maternal-like behavior in juvenile female and male rats - Physiol. Behav.
SK2 channels in cerebellar Purkinje cells contribute to excitability modulation in motor-learning-specific memory traces - PLoS Biol.
ATRX affects the repair of telomeric DSBs by promoting cohesion and a DAXX-dependent activity - PLoS Biol.
EXPRESS: CREB Depletion in Smooth Muscle Cells Promotes Medial Thickening, Adventitial Fibrosis and Elicits Pulmonary Hypertension - Pulm Circ
Tryptophan-aspartic acid-(WD)-repeat 72 (WDR72) as a regulator of endocytosis in the degradative pathway during the maturation stage of enamel formation - Thesis
Mechanisms of CD4+ Regulatory T Cell Heterogeneity in Health and Disease - Thesis
The P-Rex1 Regulator Norbin Suppressess Neutrophil-Dependent Antibacterial Immunity - Thesis
CRISPR/Cas9 engineering of albino cystinuria Type A mice - Genesis
Evaluation of Maternal, Embryo, and Placental Effects in CD-1 Mice following Gestational Exposure to Perfluorooctanoic Acid (PFOA) or Hexafluoropropylene Oxide Dimer Acid (HFPO-DA or GenX) - Environ. Health Perspect.
Inhibitory parvalbumin basket cells are selectively impaired during hippocampal sharp wave ripples in a mouse model of familial Alzheimer\'s disease - bioRxiv
Lamin B2 Levels Regulate Polyploidization of Cardiomyocyte Nuclei and Myocardial Regeneration - Dev. Cell
Modeling Mixed Vascular and Alzheimer\'s Dementia Using Focal Subcortical Ischemic Stroke in Human ApoE4-TR:5XFAD Transgenic Mice - Transl Stroke Res
Iron chelation by deferiprone does not rescue the Niemann-Pick Disease Type C1 mouse model - Biometals
Progressive cardiorespiratory dysfunction in Kv1.1 knockout mice may provide temporal biomarkers of pending sudden unexpected death in epilepsy (SUDEP): The contribution of orexin - Epilepsia
Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses - Sci Transl Med
Microbiota changes associated with ADNP deficiencies: rapid indicators for NAP (CP201) treatment of the ADNP syndrome and beyond - J Neural Transm (Vienna)
Dopaminergic Transmission Rapidly and Persistently Enhances Excitability of D1 Receptor-Expressing Striatal Projection Neurons - Neuron
Increased endogenous dopamine prevents myopia in mice - Exp. Eye Res.
Mitochondrial CaMKII causes metabolic reprogramming, energetic insufficiency, and dilated cardiomyopathy - bioRxiv
The Role of miR-155 in Myeloid cells during Experimental Autoimmune Encephalomyelitis - Thesis
Abrogation of type-I interferon signalling alters the microglial response to Aβ1-42 - Sci Rep
The parotid secretory protein BPIFA2 is a salivary surfactant that affects LPS action - bioRxiv
Ultrasonic signals associated with different types of social behavior of mice - Nat. Neurosci.
Perfluorooctanoic acid activates multiple nuclear receptor pathways and skews expression of genes regulating cholesterol homeostasis in liver of humanized PPARα mice fed an American diet - bioRxiv
Regulation of heterotopic ossification by monocytes in a mouse model of aberrant wound healing - Nat Commun
The LINC00961 transcript and its encoded micropeptide SPAAR regulate endothelial cell function - Cardiovasc. Res.
The origin and properties of pro-oncogenic fields in the intestinal epithelium - Thesis
Exploring the Importance of PREX Proteins in Glucose Homeostasis and Insulin Signalling - Thesis
Activation of Preoptic GABAergic or Glutamatergic Neurons Modulates Sleep-Wake Architecture, but Not Anesthetic State Transitions - Curr. Biol.
Maintenance DNA methylation is essential for regulatory T cell development and stability of suppressive function - bioRxiv
In vivo glucoregulation and tissue-specific glucose uptake in female Akt substrate 160 kDa knockout rats - PLOS ONE
Systemic TNF-α blockade attenuates anxiety and depressive-like behaviors in db/db mice through downregulation of inflammatory signaling in peripheral immune cells - Saudi Pharmaceutical Journal
Translational neurophysiological biomarkers of N-methyl-D-aspartate receptor dysfunction in serine racemase knockout mice - bioRxiv
Vesicular GABA-transporter neurons in the zona incerta are maximally active during non rapid-eye movement (NREM) and rapid-eye movement (REM) sleep - bioRxiv
Lipid metabolic stress in development defines which genetically-susceptible DYT-TOR1A mice develop disease - bioRxiv
Investigating Ass1 and its role in renal fibrosis - Thesis
Genetic inactivation of the translin/trax microRNA-degrading enzyme phenocopies the robust adiposity induced by Translin (Tsn) deletion - bioRxiv
An MRI-Derived Neuroanatomical Atlas of the Fischer 344 Rat Brain - Sci Rep
Primary cilia control glucose homeostasis via islet paracrine interactions - Proc. Natl. Acad. Sci. U.S.A.
Privileged scaffold-based design to identify a novel drug-like 5-HT7 receptor-preferring agonist to target Fragile X syndrome - European Journal of Medicinal Chemistry
Reduction of the RNA Binding Protein TIA1 Exacerbates Neuroinflammation in Tauopathy - Front Neurosci
Investigating glucocorticoids as mediators of increased bone marrow adiposity and bone loss - Thesis
Selective inhibition of cancer cell self-renewal through a Quisinostat-histone H1.0 axis - Nat Commun
Sleep- and time of day-linked RNA transcript expression in wild-type and IL1 receptor accessory protein null mice - J. Appl. Physiol.
Lack of Overt Retinal Degeneration in a K42E Dhdds Knock-In Mouse Model of RP59 - Cells
Discovery of novel L-type voltage-gated calcium channel blockers and application for the prevention of inflammation and angiogenesis - J Neuroinflammation
Conditional inactivation of Foxc1 and Foxc2 in neural crest cells leads to cardiac abnormalities - Genesis
Cep55 promotes cytokinesis of neural progenitors but is dispensable for most mammalian cell divisions - Nat Commun
Interaction of sexual dimorphism and gene dosage imbalance in skeletal deficits associated with Down syndrome - Bone
Activin A determines steroid levels and composition in the fetal testis - Endocrinology
Effects of optogenetic stimulation of basal forebrain parvalbumin neurons on Alzheimer\'s disease pathology - bioRxiv
Nuclear receptor CAR-ERα signaling regulates the estrogen sulfotransferase gene in the liver - Sci Rep
Actions of Rab27B-GTPase on mammalian central excitatory synaptic transmission - Physiol Rep
Passive Immunity to Vibrio cholerae O1 Afforded by a Human Monoclonal IgA1 Antibody Expressed in Milk - Pathogens and Immunity
Characterization of mWake expression in the murine brain - bioRxiv
HNF4A and GATA6 Loss Reveals Therapeutically Actionable Subtypes in Pancreatic Cancer - Cell Rep
Environmental enrichment modulates affiliative and aggressive social behaviour in the neuroligin-3 R451C mouse model of autism spectrum disorder - Pharmacol. Biochem. Behav.
The Notch Ligand Jagged1 is Required for the Formation, Maintenance, and Survival of Hensen Cells in the Mouse Cochlea - bioRxiv
Estrogen receptor α (ERα)-binding super enhancers drive key mediators that control uterine estrogen responses in mice - J. Biol. Chem.
CXCR5/NRF2 double knockout mice develop retinal degeneration phenotype at early adult age - Exp. Eye Res.
Time course of alterations in adult spinal motoneuron properties in the SOD1 (G93A) mouse model of ALS - bioRxiv
The hyperpolarization-activated cyclic nucleotide-gated 4 channel as a potential anti-seizure drug target - Br. J. Pharmacol.
Smad2/3-pathway ligand trap luspatercept enhances erythroid differentiation in murine β-thalassaemia by increasing GATA-1 availability - J. Cell. Mol. Med.
Toxoplasma gondii dense granule protein GRA24 drives MyD88-independent p38 MAPK activation, IL-12 production and induction of protective immunity - PLoS Pathog.
Respiratory Biomarkers in Kv1. 1 Knockout Mice, a Model for Temporal Lobe Epilepsy - Thesis
Multifunctional Flexible Biointerfaces for Simultaneous Colocalized Optophysiology and Electrophysiology - Adv. Funct. Mater.
Cyclin D2-knock-out mice with attenuated dentate gyrus neurogenesis have robust deficits in long-term memory formation - Sci Rep
Huntington\'s disease genotype suppresses global manganese-responsive processes in pre-manifest and manifest YAC128 mice - Metallomics
Differential Effects of RASA3 Mutations on Hematopoiesis are Profoundly Influenced by Genetic Background and Molecular Variant - bioRxiv
Sodium channel gating modifier promotes neuronal repair and functional recovery from ischemic stroke. - Thesis
Hypothalamic MCH Neuron Activity Dynamics during Cataplexy of Narcolepsy - eNeuro
Copper and the nigrostriatal pathway - Thesis
Heterogeneity in clone dynamics within and adjacent to intestinal tumours identified by Dre-mediated lineage tracing - bioRxiv
Interleukin-6 deficiency exacerbates Huntington\'s disease model phenotypes - Mol Neurodegener
Two forms of CX3CL1 display differential activity and rescue cognitive deficits in CX3CL1 knockout mice - J Neuroinflammation
A HIF1a-Dependent Pro-Oxidant State Disrupts Synaptic Plasticity and Impairs Spatial Memory in Response to Intermittent Hypoxia - eNeuro
Complex movement control in a rat model of Parkinsonian falls: bidirectional control by striatal cholinergic interneurons - J. Neurosci.
Enhancement of parvalbumin interneuron-mediated neurotransmission in the retrosplenial cortex of adolescent mice following third trimester-equivalent ethanol exposure - bioRxiv
Shear stress activates ADAM10 sheddase to regulate Notch1 via the Piezo1 force sensor in endothelial cells - Elife
Excess Lipin enzyme activity contributes to TOR1A recessive disease and DYT-TOR1A dystonia - Brain
The role of the serotonin reuptake transporter on cytoskeletal drebrin A expression in dendritic spines: Implications for neuropsychiatric disorders - Thesis
Inhibition of Angiotensin II Dependent AT1a Receptor Stimulation Attenuates Thoracic Aortic Pathology in Fibrillin-1C1041G/+ Mice - bioRxiv
THE EFFECTS OF AGARICUS BISPORUS (WHITE BUTTON MUSHROOMS) ON THE SPATIAL MEMORY, CIRCADIAN RHYTHMS, AND DAILY LIVING BEHAVIOR IN A HUMAN AMYLOID PRECURSOR PROTEIN (HAPP) MOUSE MODEL - Thesis
SHROOM3 is downstream of the planar cell polarity pathway and loss-of-function results in congenital heart defects - Dev. Biol.
Repurposing the Dihydropyridine Calcium Channel Inhibitor Nicardipine as a Nav1.8 Inhibitor In Vivo for Pitt Hopkins Syndrome - Pharm. Res.
BACH2 drives quiescence and maintenance of resting Treg cells to promote homeostasis and cancer immunosuppression - J. Exp. Med.
AP-2γ is Required for Maintenance of Pluripotent Mammary Stem Cells - bioRxiv
Genetic loss of AMPK-glycogen binding destabilizes AMPK and disrupts metabolism - Mol Metab
Time course of alterations in adult spinal motoneuron properties in the SOD1(G93A) mouse model of ALS - bioRxiv
The Effect of Chronic Methamphetamine Treatment on Schizophrenia Endophenotypes in Heterozygous Reelin Mice: Implications for Schizophrenia - Biomolecules
GENE THERAPY STRATEGIES FOR TREATMENT OF MUCO-OBSTRUCTIVE LUNG DISEASES - Thesis
Protocatechuic Acid Extends Survival, Improves Motor Function, Diminishes Gliosis, and Sustains Neuromuscular Junctions in the hSOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis - Nutrients
Excessive Homeostatic Gain in Spinal Motoneurons in a Mouse Model of Amyotrophic Lateral Sclerosis - Sci Rep
Baseline and Innate Immune Response Characterization of a Zfp30 Knockout Mouse Strain - bioRxiv
Modulation of neuroinflammation and tauopathy by RNA-binding protein TIA1 in the P301S mouse model of tauopathy - Thesis
Sex differences in biophysical signatures across molecularly defined medial amygdala neuronal subpopulations - eNeuro
Microbial Metabolism of Bile Acids Contributes to Immunological Balance in the Colon - Conference
RUNX1 marks a luminal castration resistant lineage established at the onset of prostate development - bioRxiv
SOX2 is required independently in both stem and differentiated cells for pituitary tumour genesis in p27 null mice - bioRxiv
Aged heterozygous Cdkl5 mutant mice exhibit spontaneous epileptic spasms - Exp. Neurol.
Shear stimulation of FOXC1 and FOXC2 differentially regulates cytoskeletal activity during lymphatic valve maturation - Elife
Layer 5 corticofugal projections from diverse cortical areas: variations on a pattern of thalamic and extra-thalamic targets - J. Neurosci.
Galectin-3 and the Modulation of Antitumor Immunity - Thesis
Sex Differences in the Control of Social Investigation and Anxiety by Vasopressin Cells of the Paraventricular Nucleus of the Hypothalamus - Neuroendocrinology
RNA-seq data from C-X-C chemokine receptor type 5 (CXCR5) gene knockout aged mice with retinal degeneration phenotype - Data in Brief
Transcriptome-Wide Analysis of CXCR5 Deficient Retinal Pigment Epithelial (RPE) Cells Reveals Molecular Signatures of RPE Homeostasis - Biomedicines
Vision reconstructs the cellular composition of binocular circuitry during the critical period - bioRxiv
Capillary Morphogenesis Gene Protein 2 (CMG2) Mediates Matrix Protein Uptake and is Required for Endothelial Cell Chemotaxis in Response to Multiple Vascular Growth Factors - Thesis
Investigations of an inducible intact dystrophin gene excision system in cardiac and skeletal muscle in vivo - Sci Rep
Dentate gyrus development requires a cortical hem-derived astrocytic scaffold - bioRxiv
Mutations in the iron-sulfur cluster biogenesis protein HSCB cause congenital sideroblastic anemia - J. Clin. Invest.
DTI-identified microstructural changes in the gray matter of mice overexpressing CRF in the forebrain - Psychiatry Res Neuroimaging
Suppression of proteolipid protein rescues Pelizaeus-Merzbacher disease - Nature
The effect of dietary nitrate supplementation on the speed-duration relationship in mice with sickle cell disease - J. Appl. Physiol.
Optogenetic activation of muscle contraction in vivo - bioRxiv
Peri- and Postpubertal Estrogen Exposures of Female Mice Optimize Uterine Responses Later in Life - Endocrinology
Ventricular, atrial and outflow tract heart progenitors arise from spatially and molecularly distinct regions of the primitive streak - bioRxiv
RNA-seq data from CXC chemokine receptor type 5 (CXCR5) gene knockout aged mice with retinal degeneration phenotype - Data in Brief
Collagen (I) homotrimer does not cause bone fragility but potentiates the osteogenesis imperfecta (oim) mutant allele - bioRxiv
Insulin sensing by astrocytes is critical for normal thermogenesis and body temperature regulation - J. Endocrinol.
CARD14E138A signalling in keratinocytes induces TNF-dependent skin and systemic inflammation - Elife
Retinoic acid synthesis and autoregulation mediate zonal patterning of vestibular organs and inner ear morphogenesis - Development
Myosin Va Brain-Specific Mutation Alters Mouse Behavior and Disrupts Hippocampal Synapses - bioRxiv
Silencing the intestinal GUCY2C tumor suppressor axis requires APC loss of heterozygosity - Cancer Biol. Ther.
Notch activation in the mouse mammary luminal lineage leads to ductal hyperplasia and altered partitioning of luminal cell subtypes - Exp. Cell Res.
A somatic evolutionary model of the dynamics of aneuploid cells during hematopoietic reconstitution - Sci Rep
Stress-induced Mouse Model of the Cardiac Manifestations of Friedreich\'s Ataxia Corrected by AAV-mediated Gene Therapy - Hum. Gene Ther.
Epicortical Brevetoxin Treatment Promotes Neural Repair and Functional Recovery after Ischemic Stroke - Mar Drugs
Cancer-associated fibroblasts in pancreatic ductal adenocarcinoma determine response to SLC7A11 inhibition - bioRxiv
Increased Dendritic Branching of and Reduced δ-GABAA Receptor Expression on Parvalbumin-Positive Interneurons Increase Inhibitory Currents and Reduce Synaptic Plasticity at Puberty in Female Mouse CA1 Hippocampus - Front. Cell. Neurosci.
Role of Hypoxia-Inducible Factors in Regulating Right Ventricular Function and Remodeling during Chronic Hypoxia-Induced Pulmonary Hypertension - Am. J. Respir. Cell Mol. Biol.
Preventative Effect of Mebendazole against Malignancies in Neurofibromatosis 1 - Genes (Basel)
Nf2 fine-tunes proliferation and tissue alignment during closure of the optic fissure in the embryonic mouse eye - bioRxiv
Using Conditional Deletion of Tyrosine Hydroxylase to Delineate Dopamine Subpopulations Required for Meal Anticipation on Circadian Time Scales in Mice - Thesis
The WAVE Regulatory Complex Is Required to Balance Protrusion and Adhesion in Migration - Cells
Dysfunction of parvalbumin neurons in the cerebellar nuclei produces an action tremor - J. Clin. Invest.
Vitamin D supplementation improves bone mineralisation independent of dietary phosphate in male X-linked hypophosphatemic (Hyp) mice - Bone
Intercellular Mitochondria Transfer to Macrophages Regulates White Adipose Tissue Homeostasis and Is Impaired in Obesity - Cell Metabolism
Quantifying Neurochemical Changes in Early Alzheimer\'s Disease: A Longitudinal Neuroimaging Study in the TgF344-AD Rodent Model - Thesis
Asparagine endopeptidase (δ secretase), an enzyme implicated in Alzheimer\'s disease pathology, is an inhibitor of axon regeneration in peripheral nerves - eNeuro
AP-2γ Is Required for Maintenance of Multipotent Mammary Stem Cells - Stem Cell Reports
Pulse-Chase Proteomics of the App Knockin Mouse Models of Alzheimer\'s Disease Reveals that Synaptic Dysfunction Originates in Presynaptic Terminals - Cell systems
A novel cardiomyogenic role for Isl1+ neural crest cells in the inflow tract - Science advances
Differential requirements for MDM2 E3 activity during embryogenesis and in adult mice - Genes & development
Primary cilia safeguard cortical neurons in neonatal mouse forebrain from environmental stress-induced dendritic degeneration - Proceedings of the National Academy of Sciences
Pde8b haploinsufficiency in mice is associated with modest adrenal defects, impaired steroidogenesis, and male infertility, unaltered by concurrent PKA or Wnt activation - Molecular and cellular endocrinology
Long-term spatial tracking of cells affected by environmental insults - Journal of neurodevelopmental disorders
Reward Motivation and Cognitive Flexibility in Tau Null-Mutation Mice - Neurobiology of Aging
A Theory of Nanoparticle Dosing - Thesis
Vasopressin regulates daily rhythms and circadian clock circuits in a manner influenced by sex - Hormones and Behavior
Platelet-derived growth factor beta is a potent inflammatory driver in paediatric high-grade glioma - Brain : a journal of neurology
USP28 deletion and small molecule inhibition destabilises c-Myc and elicits regression of squamous cell lung carcinoma - bioRxiv
Hippocampal network hyperexcitability in young transgenic mice expressing human mutant alpha-synuclein - Neurobiology of Disease
Multiplexed CRISPR/CAS9-mediated engineering of pre-clinical mouse models bearing native human B cell receptors - The EMBO Journal
Interleukin-6 (IL-6) deficiency enhances intramembranous osteogenesis following stress fracture in mice - Bone
Quantifying Neurochemical Changes in Early Alzheimer\'s Disease: A Longitudinal Neuroimaging Study in the TgF344-AD Rodent Model - Thesis
Ocular macrophage origin and heterogeneity during steady state and experimental choroidal neovascularization - J Neuroinflammation
Riluzole attenuates glutamatergic tone and cognitive decline in AβPP/PS1 mice - J Neurochem
Macrophage-derived vascular endothelial growth factor-A is integral to neuromuscular junction reinnervation after nerve injury - J Neurosci
The BDNF Val66Met polymorphism (rs6265) enhances dopamine neuron graft efficacy and side-effect liability in rs6265 knock-in rats - Neurobiol Dis
TRF2-independent chromosome end protection during pluripotency - Nature
X-linked cellular mosaicism underlies age-dependent occurrence of seizure-like events in mouse models of CDKL5 deficiency disorder - Neurobiol Dis
Functional Abnormalities of Cerebellum and Motor Cortex in Spinal Muscular Atrophy Mice - Neuroscience
Suppression of glycogen synthesis as a treatment for Lafora disease: Establishing the window of opportunity - Neurobiol Dis
Upregulation of nAChRs and Changes in Excitability on VTA Dopamine and GABA Neurons Correlates to Changes in Nicotine-Reward-Related Behavior - eNeuro
A MYC and RAS co-activation signature in localized prostate cancer drives bone metastasis and castration resistance - Nat Cancer
Sex differences in modulation of fetoplacental vascular resistance in growth-restricted mouse fetuses following betamethasone administration: comparisons with human fetuses - American Journal of Obstetrics & Gynecology MFM
Claudin-18 Loss Alters Transcellular Chloride Flux but not Tight Junction Ion Selectivity in Gastric Epithelial Cells - Cell Mol Gastroenterol Hepatol
Adult-born neurons in the hippocampus are essential for social memory maintenance - eNeuro
CIM6P/IGF-2 Receptor Ligands Reverse Deficits in Angelman Syndrome Model Mice - Autism Res
Impact of Zika virus on the human type I interferon osteoimmune response - Cytokine
Programmed Cell Death 2-like (Pdcd2l) Is Required for Mouse Embryonic Development - G3 (Bethesda)
Manipulation of the gut microbiota by the use of prebiotic fibre does not override a genetic predisposition to heart failure - Sci Rep
Pathogenic and therapeutic role for NRF2 signaling in ultraviolet light-induced skin pigmentation - JCI Insight
Testing broad-spectrum and isoform-preferring HCN channel blockers for anticonvulsant properties in mice - Epilepsy Res
Deficiency of C-X-C chemokine receptor type 5 (CXCR5) gene causes dysfunction of retinal pigment epithelium cells - Lab Invest
The Developmental Role of Serotonin: A Comparison of Short-and Long-term Blockade of the Serotonin Transporter on Behavioural Outcomes in Adulthood - Thesis
The Arp2/3 complex is critical for colonisation of the mouse skin by melanoblasts - Development
Sphingomyelinase Disables Inactivation in Endogenous PIEZO1 Channels - Cell Rep
Kras mutation rate precisely orchestrates ductal derived pancreatic intraepithelial neoplasia and pancreatic cancer - Lab Invest
The Influence of the LINC00961/SPAAR Locus Loss on Murine Development, Myocardial Dynamics, and Cardiac Response to Myocardial Infarction - Preprint
Vision Changes the Cellular Composition of Binocular Circuitry during the Critical Period - Neuron
Apolipoprotein A-I in mouse cerebrospinal fluid derives from the liver and intestine via plasma high-density lipoproteins assembled by ABCA1 and LCAT - FEBS Lett
Removal of Vasopressin cells from the Paraventricular Nucleus of the Hypothalamus enhances LPS‐induced sickness behavior in mice - Journal of Neuroendocrinology
Metabolic consequences for mice lacking Endosialin: LC-MS/MS-based metabolic phenotyping of serum from C56Bl/6J Control and CD248 knock-out mice - Metabolomics : Official journal of the Metabolomic Society
FMRP regulates the subcellular distribution of cortical dendritic spine density in a non-cell-autonomous manner - Neurobiology of Disease
Alzheimer’s disease-associated β-Amyloid does not protect against Herpes Simplex Virus 1 brain infection - bioRxiv
Genetic Knockout of the Serotonin Reuptake Transporter Results in the Reduction of Dendritic Spines in In vitro Rat Cortical Neuronal Culture - Journal of molecular neuroscience : MN
Investigating the Complex Interplay Between Genotype and High Fat Diet Feeding in the Lactating Mammary Gland using the Tph1and Ldlr knockout models - American journal of physiology. Endocrinology and metabolism
The Sertoli cell expressed gene secernin-1 (Scrn1) is dispensable for male fertility in the mouse - Developmental dynamics : an official publication of the American Association of Anatomists
Widespread inhibitory projections from the interposed cerebellar nucleus - bioRxiv
NOTCH Signaling Controls Ciliary Body Morphogenesis and Secretion by Directly Regulating Nectin Protein Expression - Cell Reports
Generation of an Allelic Series at the Ahr Locus Using an Edited Recombinant Approach - Toxicological sciences : an official journal of the Society of Toxicology
scRNA-sequencing reveals new enteric nervous system roles for GDNF, NRTN, and TBX3 - Cellular and Molecular Gastroenterology and Hepatology
AAV-Txnip prolongs cone survival and vision in mouse models of retinitis pigmentosa - bioRxiv
Type 1 dopamine receptor (D1R)-independent circadian food anticipatory activity in mice - PLOS ONE
Differential Effects of Trp53 Alterations in Murine Colorectal Cancer - Cancers
Enteric helminth coinfection enhances host susceptibility to neurotropic flaviviruses via a tuft cell-IL-4 receptor signaling axis - Cell
Rod photoreceptors avoid saturation in bright light by the movement of the G protein transducin - The Journal of neuroscience : the official journal of the Society for Neuroscience
miR-142-3p Regulates Cortical Oligodendrocyte Gene Co-expression Networks Associated with Tauopathy - Human Molecular Genetics
Optogenetic brain-stimulation reward: A new procedure to re-evaluate the rewarding versus aversive effects of cannabinoids in dopamine transporter-Cre mice - Addiction Biology
Type 1 diabetic Akita mice have low bone mass and impaired fracture healing - Bone
The role of aquaporin-4 in optic nerve head astrocytes in experimental glaucoma - PLOS ONE
A hepatitis B virus transgenic mouse model with a conditional, recombinant, episomal genome - JHEP Reports
Deep Learning-Based Annotation Transfer between Molecular Imaging Modalities: An Automated Workflow for Multimodal Data Integration - Analytical chemistry
Intracellular Hedgehog signaling controls Th17 polarization and pathogenicity - Research Square
Global deletion of NTPDase3 protects against diet-induced obesity by increasing basal energy metabolism - Metabolism: clinical and experimental
TRV130 partial agonism and capacity to induce antinociceptive tolerance revealed through reducing available μ opioid receptor number - British journal of pharmacology
Age of peak performance differs by functional task in mice tracked over two years - The journals of gerontology. Series A, Biological sciences and medical sciences
Diet and companionship modulate pain via a serotonergic mechanism - Scientific Reports
Novel Insights from Fetal and Placental Phenotyping in Three Mouse Models of Down Syndrome - American journal of obstetrics and gynecology
Monocyte-derived S1P in the lymph node regulates immune responses - Nature
Feasibility of cerium-doped LSO particles as a scintillator for X-ray induced optogenetics - Journal of neural engineering
Endothelin B receptors impair baroreflex function and increase blood pressure variability during high salt diet - Autonomic Neuroscience
Carbonyl reductase 1 amplifies glucocorticoid action in adipose tissue and impairs glucose tolerance in lean mice - Molecular Metabolism
Maternal Iron Deficiency Modulates Placental Transcriptome and Proteome in Mid-Gestation of Mouse Pregnancy - The Journal of nutrition
The Impacts of Age and Sex in a Mouse Model of Childhood Narcolepsy - Frontiers in Neuroscience
Alzheimer\'s disease pathology is associated with earlier alterations to blood-brain barrier water permeability compared with healthy ageing in TgF344-AD rats - NMR in biomedicine
Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol - PLoS Pathogens
Respiratory effects of low and high doses of fentanyl in control and β-arrestin 2 deficient mice - Journal of Neurophysiology
NF-κB activation in retinal microglia is involved in the inflammatory and neovascularization signaling in laser-induced choroidal neovascularization in mice - Experimental Cell Research
Stage-dependent effects of intermittent hypoxia influence the outcome of hippocampal adult neurogenesis - Scientific Reports
PI3Kδ Forms Distinct Multiprotein Complexes at the TCR Signalosome in Naïve and Differentiated CD4+ T Cells - Frontiers in Immunology
PDGFRα: Expression and Function during Mitral Valve Morphogenesis - Journal of Cardiovascular Development and Disease
Epicutaneous Staphylococcus aureus induces IL-36 to enhance IgE production and ensuing allergic disease - The Journal of clinical investigation
Characterization of in vitro models of SLC30A10 deficiency - Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine
Immune Receptor Toll-like Receptor 4 Contributes to Stress-induced Affective Responses in a Sex-specific Manner - Brain, Behavior, & Immunity - Health
Novelty-induced Hyperactivity and Suppressed Cocaine Induced Locomotor Activation in Mice Lacking Threonine 53 Phosphorylation of Dopamine Transporter - Behavioural Brain Research
Long-term effects of young-adult methamphetamine on dorsal raphe serotonin systems in mice: Role of brain-derived neurotrophic factor - Brain Research
Injury-mediated stiffening persistently activates muscle stem cells through YAP and TAZ mechanotransduction - Science advances
Norovirus evolution in immunodeficient mice reveals potentiated pathogenicity via a single nucleotide change in the viral capsid - PLoS Pathogens
Epithelial Mutant p53 Promotes Resistance to Anti-PD-1-Mediated Oral Cancer Immunoprevention in Carcinogen-Induced Mouse Models - Cancers
Apolipoprotein E genotype-dependent nutrigenetic effects to prebiotic inulin for modulating systemic metabolism and neuroprotection in mice via gut-brain axis - Nutritional Neuroscience
Cannabinoid CB2 receptors are expressed in glutamate neurons in the red nucleus and functionally modulate motor behavior in mice - Neuropharmacology
Astrocytic glycogen accumulation drives the pathophysiology of neurodegeneration in Lafora disease - Brain : a journal of neurology
RAC1B modulates intestinal tumourigenesis via modulation of WNT and EGFR signalling pathways - Nature Communications
Cholinergic neurons constitutively engage the ISR for dopamine modulation and skill learning in mice - Science (New York, N.Y.)
Gamma rhythms and visual information in mouse V1 specifically modulated by somatostatin+ neurons in reticular thalamus - Elife
Temporal contribution of myeloid-lineage TLR4 to the transition to chronic pain: A focus on sex differences - The Journal of neuroscience : the official journal of the Society for Neuroscience
Gain-of-function Lrp5 Mutation Improves Bone Mass and Strength and Delays Hyperglycemia in a Mouse Model of Insulin-Deficient Diabetes - Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Serotonin Transporter Ala276 Mouse: Novel Model to Assess the Neurochemical and Behavioral Impact of Thr276 Phosphorylation In Vivo - Neurochemical Research
Distinct Basal Metabolism in Three Mouse Models of Neurodevelopmental Disorders - eNeuro
Exploring the Role of an Adipocyte-Specific Knockout of MHCII on Inflammatory-Driven Complications of Obesity in Female Pro-atherogenic Mice - Thesis
Glutamatergic Neurons in the Preoptic Hypothalamus Promote Wakefulness, Destabilize NREM Sleep, Suppress REM Sleep, and Regulate Cortical Dynamics - The Journal of neuroscience : the official journal of the Society for Neuroscience
Immune-regulated IDO1-dependent tryptophan metabolism is source of one-carbon units for pancreatic cancer and stellate cells - Molecular Cell
Neuroimaging, Urinary, and Plasma Biomarkers of Treatment Response in Huntington\'s Disease: Preclinical Evidence with the p75NTR Ligand LM11A-31 - Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
SUR1, newly expressed in astrocytes, mediates neuropathic pain in a mouse model of peripheral nerve injury - Molecular pain
SK2 Channel and Metabotropic Receptor Mediated Regulation of Intrinsic Excitability in Purkinje Cells and Implications for Cerebellar Learning - Thesis
Early Isoflurane Exposure Impairs Synaptic Development in Fmr1 KO Mice via the mTOR Pathway - Neurochemical Research
CCR8 marks highly suppressive Treg cells within tumours but is dispensable for their accumulation and suppressive function - Immunology
Differential effects by sex with Kmt5b loss - Autism research : official journal of the International Society for Autism Research
Alzheimer\'s disease-associated β-Amyloid does not protect against Herpes Simplex Virus 1 infection in the mouse brain - The Journal of biological chemistry
Role of IL-36γ/IL-36R Signaling in Corneal Innate Defense Against Candida albicans Keratitis - Investigative ophthalmology & visual science
Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity - Cell
Enhanced epithelial sodium channel activity in neonatal Scnn1b mouse lung attenuates high oxygen induced lung injury - American journal of physiology. Lung cellular and molecular physiology
Metabolic reprogramming of terminally exhausted CD8+ T cells by IL-10 enhances anti-tumor immunity - Nature Immunology
Introducing ADNP and SIRT1 as new partners regulating microtubules and histone methylation - Molecular Psychiatry
Endothelial IGF-1 receptor mediates crosstalk with the gut wall to regulate microbiota in obesity - EMBO reports
Defective apoptotic cell contractility provokes sterile inflammation, leading to liver damage and tumour suppression - Elife
Estrogen receptor β contributes to both hypertension and hypothalamic plasticity in a mouse model of peri-menopause - The Journal of neuroscience : the official journal of the Society for Neuroscience
Endogenous p53 expression in human and mouse is not regulated by its 3\'UTR - Elife
Transferrable protection by gut microbes against STING-associated lung disease - Cell Reports
Mouse models for dominant dystrophic epidermolysis bullosa (DDEB) carrying common human point mutations recapitulate the human disease - Disease Models & Mechanisms
Endothelial insulin receptors promote VEGF-A signaling via ERK1/2 and sprouting angiogenesis - Endocrinology
Reduction in vasopressin cells in the suprachiasmatic nucleus in mice increases anxiety and alters fluid intake - Hormones and Behavior
An aged immune system drives senescence and ageing of solid organs - Nature
Intrinsic functional neuron-type selectivity of transcranial focused ultrasound neuromodulation - Nature Communications
Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver - Science advances
Mice with an autism-associated R451C mutation in neuroligin-3 show a cautious but accurate response style in touchscreen attention tasks - Genes, brain, and behavior
GRSF1 deficiency in skeletal muscle reduces endurance in aged mice - Aging
Arrdc4-dependent extracellular vesicle biogenesis is required for sperm maturation - Journal of extracellular vesicles
Survival Bias and Crosstalk between Chronological and Behavioral Age: Age- and Genotype-Sensitivity Tests Define Behavioral Signatures in Middle-Aged, Old, and Long-Lived Mice with Normal and AD-Associated Aging - Biomedicines
The atypical small GTPase GEM/Kir is a negative regulator of the NADPH oxidase and NETs production through macroautophagy - Journal of leukocyte biology
Notch-IGF1 signaling during liver regeneration drives biliary epithelial cell expansion and inhibits hepatocyte differentiation - Science Signaling
Lactobacillus rhamnosus GG Orchestrates an Anti-tumor Immune Response - Cellular and Molecular Gastroenterology and Hepatology
Active Rap1-mediated inhibition of choroidal neovascularization requires interactions with IQGAP1 in choroidal endothelial cells - FASEB journal : official publication of the Federation of American Societies for Experimental Biology
The role of the PWWP domain in the DNA methyltransferase 3A targeting to the genome - Thesis
Dietary Vitamin C and Age-Induced Lipid and Hormonal Metabolic Changes in a Humanized Mouse Model Not Synthesizing Vitamin C and Producing Lipoprotein(a) [Gulo (−/−); Lp(a)+] - Journal of Nutrition and Metabolism
The transcription factor Sox2 is required to maintain the cell type-specific properties and innervation of type II vestibular hair cells in adult mice - The Journal of neuroscience : the official journal of the Society for Neuroscience
Coding and Noncoding Modalities of LncRNA Function - Thesis
Dissecting indirect genetic effects from peers in laboratory mice - Genome Biology
Primed to die: an investigation of the genetic mechanisms underlying noise-induced hearing loss and cochlear damage in homozygous Foxo3-knockout mice - Cell death & disease
Tissue-specific expression of Cas9 has no impact on whole-body metabolism in four transgenic mouse lines - Molecular Metabolism
The Src-family kinase Lyn in immunoreceptor signaling - Endocrinology
Differential NPY-Y1 Receptor Density in the Motor Cortex of ALS Patients and Familial Model of ALS - Brain Sciences
Bioluminescent Optogenetics: A Novel Experimental Therapy to Promote Axon Regeneration after Peripheral Nerve Injury - International Journal of Molecular Sciences
Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity - Cancer Cell
ImmTOR nanoparticles enhance AAV-driven transgene expression after initial and repeat dosing in a mouse model of methylmalonic acidemia - Molecular Therapy - Methods & Clinical Development
Reduced sociability and social agency encoding in adult Shank3-mutant mice are restored through gene re-expression in real time - Nature Neuroscience
Red Blood Cell and Endothelial eNOS Independently Regulate Circulating Nitric Oxide Metabolites and Blood Pressure - Circulation
Characterization and allogeneic transplantation of a novel transgenic cone-rich donor mouse line - Experimental Eye Research
Transcriptome analysis using patient iPSC-derived skeletal myocytes: Bet1L as a new molecule possibly linked to neuromuscular degeneration in ALS - Experimental Neurology
Combinatorial actions of glucocorticoid and mineralocorticoid stress hormone receptors are required for preventing neurodegeneration of the mouse hippocampus - Neurobiology of Stress
Addressing an Unmet Need: Rigorous Examination of Motor as a Translational Outcome in Preclinical Models for Neurodevelopmental Disorders - Thesis
Enduring glucocorticoid-evoked exacerbation of synaptic plasticity disruption in male rats modelling early Alzheimer\'s disease amyloidosis - Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Perfluorooctanoic acid induces liver and serum dyslipidemia in humanized PPARα mice fed an American diet - Toxicology and Applied Pharmacology
Ketogenic diet-mediated seizure reduction preserves CA1 cell numbers in epileptic Kcna1-null mice: An unbiased stereological assessment - Epilepsia
A genetic basis for friendship? Homophily for membrane-associated PDE11A-cAMP-CREB signaling in CA1 of hippocampus dictates mutual social preference in male and female mice - Molecular Psychiatry
4-Phenylbutyrate Restores Localization and Membrane Repair to Human Dysferlin Mutation - SSRN Electronic Journal
Mebendazole disrupts stromal desmoplasia and tumorigenesis in two models of pancreatic cancer - Oncotarget
The effects of Cstb duplication on APP/amyloid-β pathology and cathepsin B activity in a mouse model - PLOS ONE
Circuit-specific enteric glia regulate intestinal motor neurocircuits - Proceedings of the National Academy of Sciences of the United States of America
Role of fibulin-5 insufficiency and prolapse progression on murine vaginal biomechanical function - Scientific Reports
High fat diet causes inferior vertebral structure and function without disc degeneration in RAGE-KO mice - Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Influence of traumatic brain injury on extracellular tau elimination at the blood-brain barrier - Fluids and barriers of the CNS
Preventing adolescent synaptic pruning in mouse prelimbic cortex via local knockdown of α4βδ GABAA receptors increases anxiety response in adulthood - Scientific Reports
GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis - Science advances
Negative regulation of TGFβ-induced apoptosis by RAC1B enhances intestinal tumourigenesis - Cell death & disease
Experiential modulation of social dominance in a SYNGAP1 rat model of Autism Spectrum Disorders - The European journal of neuroscience
p53-mediated redox control promotes liver regeneration and maintains liver function in response to CCl4 - Cell Death and Differentiation
Loss of mTORC2-induced metabolic reprogramming in monocytes uncouples migration and maturation from production of proinflammatory mediators - Journal of leukocyte biology
Baclofen-Associated Neurophysiologic Target Engagement Across Species in Fragile X Syndrome - Research Square
Diverse inhibitory projections from the cerebellar interposed nucleus - Elife
Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis - The Journal of experimental medicine
Genetic targeting of adult Renshaw cells using a Calbindin 1 destabilized Cre allele for intersection with Parvalbumin or Engrailed1 - Scientific Reports
Vascular Smooth Muscle Cell Subpopulations and Neointimal Formation in Mouse Models of Elastin Insufficiency - Arteriosclerosis, thrombosis, and vascular biology
A brain-specific pgc1α fusion transcript affects gene expression and behavioural outcomes in mice - Life science alliance
Fibrinogen αC-subregions critically contribute blood clot fibre growth, mechanical stability, and resistance to fibrinolysis - Elife
Increased 2-arachidonoyl-sn-glycerol levels normalize cortical responses to sound and improve behaviors in Fmr1 KO mice - Journal of neurodevelopmental disorders
Novel Impacts of Host-Environment Interactions in Enteric Glia Through Sequencing and in-situ Expression - Thesis
Regulation of intestinal immunity and tissue repair by enteric glia - Nature
Spred1 deficit promotes treatment resistance and transformation of chronic phase CML - Leukemia
USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma - Elife
Angiotensin-II Signaling in the Pars Reticulata GABA-Ergic Neurons in the Substantia Nigra and Its Implications in Nigral Neurotransmission - Thesis
Temporal manipulation of Cdkl5 reveals essential postdevelopmental functions and reversible CDKL5 deficiency disorder-related deficits - The Journal of clinical investigation
Evidence for layer-specific connectional heterogeneity in the mouse auditory corticocollicular system - The Journal of neuroscience : the official journal of the Society for Neuroscience
Adolescence in the Development of the Prefrontal Cortex and Mediodorsal Thalamus - Thesis
Pharmacoresponsiveness of spontaneous recurrent seizures and the comorbid sleep disorder of epileptic Kcna1-null mice - European journal of pharmacology
Generation and analysis of innovative genomically humanized knockin SOD1, TARDBP (TDP-43), and FUS mouse models - iScience
KATNB1 is a master regulator of multiple katanin enzymes in male meiosis and haploid germ cell development - Development (Cambridge, England)
Growth and Mechanobiology of the Achilles Enthesis in Mice - Thesis
Synaptic Zn2+ potentiates the effects of cocaine on striatal dopamine neurotransmission and behavior - Translational Psychiatry
Small molecule modulation of TrkB and TrkC neurotrophin receptors prevents cholinergic neuron atrophy in an Alzheimer's disease mouse model at an advanced pathological stage - Neurobiology of Disease
Smad4 controls signaling robustness and morphogenesis by differentially contributing to the Nodal and BMP pathways - Nature Communications
Inhaled gene therapy of preclinical muco-obstructive lung diseases by nanoparticles capable of breaching the airway mucus barrier - Thorax
Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies - Immunity
The Role of Fibroblast Growth Factor Signaling during Superstructure Development and in Muscle-Bone Crosstalk - Thesis
Neutrophil DREAM promotes neutrophil recruitment in vascular inflammation - The Journal of experimental medicine
The neuropeptide alpha-melanocyte-stimulating hormone is critical for corneal endothelial cell protection and graft survival after transplantation - The American journal of pathology
Differential effects of chronic stress on anxiety-like behavior and contextual fear conditioning in the TgF344-AD rat model of Alzheimer's disease - Behavioural Brain Research
SARS-CoV-2 B.1.1.7 (alpha) and B.1.351 (beta) variants induce pathogenic patterns in K18-hACE2 transgenic mice distinct from early strains - Nature Communications
An innate contribution of human nicotinic receptor polymorphisms to COPD-like lesions - Nature Communications
Might Routine Vitamin A Monitoring in Cystic Fibrosis Patients Reduce Virus-Mediated Lung Pathology? - Frontiers in Immunology
The role of β2 adrenergic receptor on infection development after ischaemic stroke - Brain, Behavior, & Immunity - Health
ATP-sensitive potassium channels in zebrafish cardiac and vascular smooth muscle - The Journal of Physiology
Neuropilin 1 regulates bone marrow vascular regeneration and hematopoietic reconstitution - Nature Communications
Müller glial responses compensate for degenerating photoreceptors in retinitis pigmentosa - Experimental & molecular medicine
Patterns of cognitive decline and somatosensory processing in a mouse model of amyloid accumulation - Neurobiology of pain (Cambridge, Mass.)
Inhibition of the renin-angiotensin system causes concentric hypertrophy of renal arterioles in mice and humans - JCI Insight
The Exercise-induced Improvement in Insulin-stimulated Glucose Uptake by Rat Skeletal Muscle Is Absent in Male AS160-Knockout Rats, Partially Restored by Muscle Expression of Phosphomutated AS160, and Fully Restored by Muscle Expression of Wildtype AS160 - Diabetes
A Gene-environment Interaction Model of Schizophrenia: Maternal Immune Activation in miR-137 Mutant Mice - Thesis
Programmed Cell Death Recruits Macrophages Into the Developing Mouse Cochlea - Frontiers in cell and developmental biology
Compromised fractalkine signaling delays microglial occupancy of emerging modules in the multisensory midbrain - Glia
Decision letter: A functional topography within the cholinergic basal forebrain for encoding sensory cues and behavioral reinforcement outcomes - yulonglilab.org
EphA2 and Ephrin-A5 Guide Eye Lens Suture Alignment and Influence Whole Lens Resilience - Investigative ophthalmology & visual science
Local non-pituitary growth hormone is induced with aging and facilitates epithelial damage - Cell Reports
Sex-specific differences in direct osteoclastic versus indirect osteoblastic effects underlay the low bone mass of Pannexin1 deletion in TRAP-expressing cells in mice - Bone Reports
CRISPR-Cas9 effectors facilitate generation of single-sex litters and sex-specific phenotypes - Nature Communications
Vitamin D binding protein greatly improves bioactivity but is not essential for orally administered vitamin D - Physiological Reports
Natural rodent model of viral transmission reveals biological features of virus population dynamics - The Journal of experimental medicine
Shiftless inhibits flavivirus replication in vitro and is neuroprotective in a mouse model of Zika virus pathogenesis - Proceedings of the National Academy of Sciences of the United States of America
Xenogeneic skin transplantation promotes angiogenesis and tissue regeneration through activated Trem2+ macrophages - Science advances
A Role for NRF2-Signaling in the Treatment and Prevention of Solar Lentigines - Plastic and reconstructive surgery
Rpl24Bst mutation suppresses colorectal cancer by promoting eEF2 phosphorylation via eEF2K - Elife
Design and Functional Validation of Mouse Models of Human Burkitt Lymphoma - Thesis
Early lysosome defects precede neurodegeneration with amyloid-β and tau aggregation in NHE6-null rat brain - Brain : a journal of neurology
Mitochondrial calcium uniporter affects neutrophil bactericidal activity during Staphylococcus aureus infection - Infection and Immunity
Cocoa Extract Exerts Sex-Specific Effects in an Aggressive Hyper-Glycemia Model: A Pilot Study - Preprint
Phagosomal chloride dynamics in the alveolar macrophage - iScience
A functional topography within the cholinergic basal forebrain for encoding sensory cues and behavioral reinforcement outcomes - Elife
4-Phenylbutyrate restores localization and membrane repair to human dysferlin mutations - iScience
Prior Chronic Methamphetamine Treatment and Gp120 Expression Additively Reduce PPI in Aged Male But Not Female Mice - SSRN Electronic Journal
Ferroptosis mediates selective motor neuron death in amyotrophic lateral sclerosis - Cell Death and Differentiation
Loss of αA or αB-Crystallin Accelerates Photoreceptor Cell Death in a Mouse Model of P23H Autosomal Dominant Retinitis Pigmentosa - International Journal of Molecular Sciences
An HDAC6 inhibitor reverses chemotherapy-induced mechanical hypersensitivity via an IL-10 and macrophage dependent pathway - Brain, Behavior, and Immunity
LPAR1 regulates enteric nervous system function through glial signaling and contributes to chronic intestinal pseudo-obstruction - The Journal of clinical investigation
Contribution of the innate and adaptive immune systems to aortic dilation in murine mucopolysaccharidosis type I - Molecular genetics and metabolism
Capillary morphogenesis gene 2 (CMG2) mediates growth factor-induced angiogenesis by regulating endothelial cell chemotaxis - Angiogenesis
Proglumide Reverses Nonalcoholic Steatohepatitis by Interaction with the Farnesoid X Receptor and Altering the Microbiome - International Journal of Molecular Sciences
Differential Expression of Presynaptic Munc13-1 and Munc13-2 in Mouse Hippocampus Following Ethanol Drinking - Neuroscience
Human biliary epithelial cells from discarded donor livers rescue bile duct structure and function in a mouse model of biliary disease - Cell Stem Cell
A noninvasive iRFP713 p53 reporter reveals dynamic p53 activity in response to irradiation and liver regeneration in vivo - Science Signaling
The impact of pimavanserin on psychotic phenotypes and tau phosphorylation in the P301L/COMT- and rTg(P301L)4510 mouse models of Alzheimer's disease - Alzheimer's & dementia (New York, N. Y.)
WDR72 regulates vesicle trafficking in ameloblasts - Scientific Reports
Differential sleep/wake response and sex differences following acute suvorexant, MK-1064 and zolpidem administration in the rTg4510 mouse model of tauopathy - British journal of pharmacology
SLAMF1 Is Dispensable for Vaccine-Induced T Cell Development but Required for Resistance to Fungal Infection - Journal of immunology (Baltimore, Md. : 1950)
The minor allele of the CREBRF rs373863828 p.R457Q coding variant is associated with reduced levels of myostatin in males: Implications for body composition - Molecular Metabolism
Integrin α5 Is Regulated by miR-218-5p in Endothelial Progenitor Cells - Journal of the American Society of Nephrology : JASN
Slow oscillations persist in pancreatic beta cells lacking phosphofructokinase M - Biophysical journal
DCHS1, Lix1L, and the Septin Cytoskeleton: Molecular and Developmental Etiology of Mitral Valve Prolapse - Journal of Cardiovascular Development and Disease
ATase inhibition rescues age-associated proteotoxicity of the secretory pathway - Communications Biology
Aldehyde dehydrogenase 2 activator augments the beneficial effects of empagliflozin in diabetes associated HFpEF - Research Square
Loss of RARRES1 function Promotes Follicular Lymphomagenesis and Inhibits B cell Differentiation in Mice - ijbs.com
Chemopreventive Efficacy of Silibinin against Basal Cell Carcinoma Growth and Progression in UVB-irradiated Ptch +/- mice - Carcinogenesis
Voltage imaging in the olfactory bulb using transgenic mouse lines expressing the genetically encoded voltage indicator ArcLight - Scientific Reports
Pathway-specific TNF-mediated metaplasticity in hippocampal area CA1 - Scientific Reports
NaV1.1 haploinsufficiency impairs glutamatergic and GABAergic neuron function in the thalamus - Neurobiology of Disease
Endothelial Notch signaling directly regulates the small GTPase RND1 to facilitate Notch suppression of endothelial migration - Scientific Reports
The Dp16 Mouse Model of Down Syndrome: Phenotypic Characterization and Assessment of the Pro-Cognitive Agent RIV5061 - Thesis
Optogenetic stimulation of dynorphinergic neurons within the dorsal raphe activate kappa opioid receptors in the ventral tegmental area and ablation of dorsal raphe prodynorphin or kappa receptors in dopamine neurons blocks stress potentiation of cocaine reward - Addiction Neuroscience
Antisense oligonucleotide-based therapeutic strategy for progranulin-deficient frontotemporal dementia - bioRxiv
Detecting microRNA-mediated gene regulatory effects in murine neuronal subpopulations - STAR Protocols
Morphine exposure reduces nicotine-induced upregulation of nicotinic receptors and decreases volitional nicotine intake in a mouse model - Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Endothelial Piezo1 sustains muscle capillary density and contributes to physical activity - The Journal of clinical investigation
EphA2 Affects Development of the Eye Lens Nucleus and the Gradient of Refractive Index - Investigative ophthalmology & visual science
VCP/p97 inhibitor CB-5083 modulates muscle pathology in a mouse model of VCP inclusion body myopathy - Journal of Translational Medicine
Vision-dependent specification of cell types and function in the developing cortex - Cell
Regulation of Cutaneous Immunity In Vivo by Calcitonin Gene-Related Peptide Signaling through Endothelial Cells - Journal of immunology (Baltimore, Md. : 1950)
Estradiol mediates stress-susceptibility in the male brain - bioRxiv
Experimenter sex modulates mouse biobehavioural and pharmacological responses - bioRxiv
Ca2+ entry through mechanotransduction channels localizes BAIAP2L2 to stereocilia tips - Molecular Biology of the Cell
Human INHBB gene variant (c.1079T&gt;C:p.Met360Thr) alters testis germ cell content, but does not impact fertility in mice - Endocrinology
Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology - Nature Communications
Long-Term Imaging Reveals a Circadian Rhythm of Intracellular Chloride in Neurons of the Suprachiasmatic Nucleus - Journal of biological rhythms
Combined Kelch-Like 3 and Cullin 3 Degradation is a Central Mechanism in Familial Hyperkalemic Hypertension in Mice - Journal of the American Society of Nephrology : JASN
Polyamine import and accumulation causes immunomodulation in macrophages engulfing apoptotic cells - Cell Reports
Astrocyte immunosenescence and deficits in interleukin 10 signaling in the aged brain disrupt the regulation of microglia following innate immune activation - Glia
Real time imaging of single extracellular vesicle pH regulation in a microfluidic cross-flow filtration platform - Communications Biology
Contrast Enhanced Ultrasound Molecular Imaging of Spontaneous Chronic Inflammatory Bowel Disease in an Interleukin-2 Receptor α-/- Transgenic Mouse Model Using Targeted Microbubbles - Nanomaterials (Basel, Switzerland)
Carcinomas assemble a filamentous CXCL12-keratin-19 coating that suppresses T cell-mediated immune attack - Proceedings of the National Academy of Sciences of the United States of America
Inhibition of adult neurogenesis reduces avoidance behavior in male, but not female, mice subjected to early life adversity - Neurobiology of Stress
Pharmacogenetic inhibition of lumbosacral sensory neurons alleviates visceral hypersensitivity in a mouse model of chronic pelvic pain - PLOS ONE
MicroPET evidence for a hypersensitive neuroinflammatory profile of gp120 mouse model of HIV - Psychiatry research. Neuroimaging
Sex- and Genotype-Dependent Nicotine-Induced Behaviors in Adolescent Rats with a Human Polymorphism (rs2304297) in the 3'-UTR of the CHRNA6 Gene - International Journal of Molecular Sciences
HLA Mice as a Model to Study T Cell Responses Restricted by Human MHC - Conference
Extracellular Superoxide Dismutase (EC-SOD) R213G variant reduces mitochondrial ROS and preserves mitochondrial function in bleomycin-induced lung injury - Free Radical Biology and Medicine
Neurochemical and cognitive changes precede structural abnormalities in the TgF344-AD rat model - Brain Communications
Differential effects of early or late exposure to prenatal maternal immune activation on mouse embryonic neurodevelopment - Proceedings of the National Academy of Sciences of the United States of America
Diabetic bladder dysfunction progresses from an overactive to an underactive phenotype in a type-1 diabetic mouse model (Akita female mouse) and is dependent on NLRP3 - Life Sciences
Behavioral phenotyping of a rat model of the BDNF Val66Met polymorphism reveals selective impairment of fear memory - Translational Psychiatry
Combination treatment with growth hormone and zoledronic acid in a mouse model of Osteogenesis imperfecta - Bone
LYNPARZA®(olaparib) reduced risk of death by 32% in the adjuvant treatment of patients with germline BRCA-mutated high-risk early breast cancer - lelezard.com
LYNPARZA®(olaparib) approved in the US as adjuvant treatment for patients with germline BRCA-mutated HER2-negative high-risk early breast cancer - lelezard.com
Dopamine Dysregulation and Altered Responses to Drugs Affecting Dopaminergic Transmission in a New Dopamine Transporter Knockout (DAT-KO) Rat Model - Neuroscience
Glutathione deficiency decreases lipid droplet stores and increases reactive oxygen species in mouse oocytes† - Biology of reproduction
Investigation of Mechanisms of Low Intensity Transcranial Focused Ultrasound Stimulation in the Central Nervous System of in Vivo Rodent Models - Thesis
Sub-lethal apoptotic stress enables mtDNA release during senescence and drives the SASP - Research Square
Differential effects of chronic adolescent glucocorticoid or methamphetamine on drug-induced locomotor hyperactivity and disruption of prepulse inhibition in adulthood in mice - Progress in neuro-psychopharmacology & biological psychiatry
Synapsin II Directly Suppresses Epileptic Seizures In Vivo - Brain Sciences
Listeria delivers tetanus toxoid protein to pancreatic tumors and induces cancer cell death in mice - Science Translational Medicine
The Development of Receptive Field Tuning Properties in Mouse Binocular Primary Visual Cortex - The Journal of neuroscience : the official journal of the Society for Neuroscience
Inhibin Inactivation in Female Mice Leads to Elevated FSH Levels, Ovarian Overstimulation, and Pregnancy Loss - Endocrinology
Tsc2 knockout counteracts ubiquitin-proteasome system insufficiency and delays photoreceptor loss in retinitis pigmentosa - Proceedings of the National Academy of Sciences of the United States of America
Molecular Identity Changes of Tumor-Associated Macrophages and Microglia after MRgFUS induced BBB Opening in a Mouse Glioblastoma Model - Research Square
Global PIEZO1 Gain-of-Function Mutation Causes Cardiac Hypertrophy and Fibrosis in Mice - Cells
The Classic Diet-Induced Obese Mouse Model is Still Enabling Breakthroughs in Drug Discovery for Metabolic Diseases - Conference
Applications of Visible-Light Optical Coherence Tomography in the Eye and Brain - Thesis
A dominant function of LynB kinase in preventing autoimmunity - Science advances
IL-13Rα1-Mediated Signaling Regulates Age-Associated/Autoimmune B-Cell Expansion and Lupus Pathogenesis - Arthritis & rheumatology (Hoboken, N.J.)
In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration - Nature Communications
The Role of Electronic Nicotine Delivery System (ENDS) Flavorants on Nicotine Addiction and Neurological Function - Thesis
Cannabinoid Receptor 1 Is Required for Neurodevelopment of Striosome-Dendron Bouquets - eNeuro
The same stress elicits different effects on anxiety-like behavior in rat models of Fmr1-/y and Pten+/ - Behavioural Brain Research
Autoreactive memory Th17 cells are principally derived from T-bet+RORγt+ Th17/1 effectors - Journal of Autoimmunity
Optical investigation of microcircuit computations in mouse primary visual cortex - Thesis
Combined prior chronic methamphetamine treatment and gp120 expression reduce PPI in aged male but not female mice - Neuroscience Letters
Macrophages Actively Transport Nanoparticles in Tumors After Extravasation - ACS nano
Mast Cells Regulate Bile Acid Signaling and Cholestasis Via Alteration of Farnesoid X Receptor/Fibroblast Growth Factor 15 Axis in Mice - Thesis
Inhibitory co-transmission from midbrain dopamine neurons relies on presynaptic GABA uptake - Cell Reports
Loss of Function of WFS1 Causes ER Stress-Mediated Inflammation in Pancreatic Beta-Cells - Frontiers in endocrinology
USP25 promotes pathological HIF-1-driven metabolic reprogramming and is a potential therapeutic target in pancreatic cancer - Nature Communications
The BDNF Val66Met Polymorphism Does Not Increase Susceptibility to Activity-Based Anorexia in Rats - Biology
Protective Effects of Cocoa Flavanols Against Obesity and Type 2 Diabetes are Influenced by Biological Sex and Host Gut Microbiome Composition. - Thesis
Characterization of stage-specific tumor progression in TMPRSS2-ERG (fusion)-driven and non-fusion-driven prostate cancer in GEM models - Molecular Carcinogenesis
Fecal Microbiota Transplantation Derived from Alzheimer’s Disease Mice Worsens Brain Trauma Outcomes in Wild-Type Controls - International Journal of Molecular Sciences
Microglial FABP4-UCP2 Axis Modulates Neuroinflammation and Cognitive Decline in Obese Mice - International Journal of Molecular Sciences
Atrial AMP-activated protein kinase is critical for prevention of dysregulation of electrical excitability and atrial fibrillation - JCI Insight
Cell-selective AAV-mediated SCN1A Gene Regulation Therapy Rescues Mortality and Seizure Phenotypes in a Dravet Syndrome Mouse Model and is Well Tolerated in Non-human Primates - Human gene therapy
VCP suppresses proteopathic seeding in neurons - Molecular Neurodegeneration
VCP: A Gatekeeper for Intracellular Proteopathic Seeding - Thesis
Glutamate released by Cajal-Retzius cells impacts specific hippocampal circuits and behaviors - Cell Reports
Endosomal structure and APP biology are not altered in a preclinical mouse cellular model of Down syndrome - PLOS ONE
Complex N-Linked Glycosylation: A Potential Modifier of Niemann-Pick Disease, Type C1 Pathology - International Journal of Molecular Sciences
Orexin as a Chemosensor: Implications on Cardiorespiration and Sudep in the Kcna1-Null Mouse Model - Thesis
Vitamin D esters are the major form of vitamin D produced by UV irradiation in mice - Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
Astrocyte Cell Surface Antigen 2 and Other Potential Cell Surface Markers of Enteric glia in the Mouse Colon - ASN neuro
RNA splicing is a key mediator of tumour cell plasticity and a therapeutic vulnerability in colorectal cancer - Nature Communications
BMI1 Silencing Induces Mitochondrial Dysfunction in Lung Epithelial Cells Exposed to Hyperoxia - Frontiers in Physiology
Cryogel Scaffold-Mediated Delivery of Adipose-Derived Stem Cells Promotes Healing in Murine Model of Atrophic Non-Union - Frontiers in bioengineering and biotechnology
Focused ultrasound excites action potentials in mammalian peripheral neurons in part through the mechanically gated ion channel PIEZO2 - Proceedings of the National Academy of Sciences of the United States of America
Ocular Hypertension Results in Hypoxia within Glia and Neurons throughout the Visual Projection - Antioxidants (Basel, Switzerland)
Maladaptive myelination promotes generalized epilepsy progression - Nature Neuroscience
A preclinical model of peripheral T-cell lymphoma GATA3 reveals DNA damage response pathway vulnerability - EMBO Molecular Medicine
Endothelial thioredoxin interacting protein (TXNIP) modulates endothelium-dependent vasorelaxation in hyperglycemia - Microvascular research
Defective AMPK regulation of cholesterol metabolism accelerates atherosclerosis by promoting HSPC mobilization and myelopoiesis - Molecular Metabolism
The Effect of Aging on Retinal Function and Retinal Ganglion Cell Morphology Following Intraocular Pressure Elevation - Frontiers in Aging Neuroscience
Ephaptic Coupling Is a Mechanism of Conduction Reserve During Reduced Gap Junction Coupling - Frontiers in Physiology
Resilient Hippocampal Gamma Rhythmogenesis and Parvalbumin-Expressing Interneuron Function Before and After Plaque Burden in 5xFAD Alzheimer’s Disease Model - Frontiers in Synaptic Neuroscience
Building a laboratory and networks during the COVID-19 pandemic - Trends in biochemical sciences
Effects of intracardiac delivery of aldehyde dehydrogenase 2 gene in myocardial salvage - Gene Therapy
MYC drives aggressive prostate cancer by disrupting transcriptional pause release at androgen receptor targets - Nature Communications
Developing a Method for the Co-expression and Co-localization of Muscarinic M4 Receptors and Dopamine D1 Receptors in the Mouse Brain: Special Focus on Sexual Dimorphism - Thesis
Ubiquitination of Ebola virus VP35 at lysine 309 regulates viral transcription and assembly - PLoS Pathogens
Establishment and resilience of transplanted gut microbiota in aged mice - iScience
Zn-regulated GTPase metalloprotein activator 1 modulates vertebrate zinc homeostasis - Cell
Enterovirus Replication and Dissemination Are Differentially Controlled by Type I and III Interferons in the Gastrointestinal Tract - mBio
Glucagon-receptor-antagonism-mediated β-cell regeneration as an effective anti-diabetic therapy - Cell Reports
EFFICACY OF PREBIOTIC DIETARY INTERVENTION TO MITIGATE RISKS FOR DEMENTIA VIA THE GUT-BRAIN AXIS - Thesis
Senescence-induced endothelial phenotypes underpin immune-mediated senescence surveillance - Genes & development
Mice blocking Ser347 phosphorylation of pregnane x receptor develop hepatic fasting-induced steatosis and hypertriglyceridemia - Biochemical and Biophysical Research Communications
The ER ladder is a unique morphological feature of developing mammalian axons - Developmental Cell
Continuous, but not intermittent, regimens of hypoxia prevent and reverse ataxia in a murine model of Friedreich's ataxia - Human Molecular Genetics
A Three-Dimensional Primary Cortical Culture System Compatible with Transgenic Disease Models, Virally Mediated Fluorescence, and Live Microscopy - Methods in molecular biology (Clifton, N.J.)
Effects of the T-type calcium channel CaV3.2 R1584P mutation on absence seizure susceptibility in GAERS and NEC congenic rats models - Neurobiology of Disease
Systemic gene therapy using an AAV44.9 vector rescues a neonatal lethal mouse model of propionic acidemia - Molecular Therapy - Methods & Clinical Development
Indoleamine 2,3-dioxygenase 1 regulates cell permissivity to astrovirus infection - Mucosal immunology
A Bioluminescent Activity Dependent (BLADe) Platform for Converting Neuronal Activity to Photoreceptor Activation - bioRxiv
ERAP1 Shows Distinct Regulatory Mechanisms on Blood Pressure Modulation Between Males and Females - bioRxiv : the preprint server for biology
Reciprocal effects of alpha-synuclein aggregation and lysosomal homeostasis in synucleinopathy models - Translational neurodegeneration
Independent endothelial functions of PIEZO1 and TRPV4 in hepatic portal vein and predominance of PIEZO1 in mechanical and osmotic stress - Liver international : official journal of the International Association for the Study of the Liver
Gene-nutrient interactions that impact magnesium homeostasis increase risk for neural tube defects in mice exposed to dolutegravir - Frontiers in cell and developmental biology
Codon bias and tRNA adaptation in antibody production - Thesis
Genetic and immune determinants ofE. coliliver abscess formation - bioRxiv
Purinergic P2Y2 Receptor-Induced Activation of Endothelial TRPV4 Channels Mediates Lung Ischemia-Reperfusion Injury - bioRxiv
Fibrocytes enhance mammary gland fibrosis in obesity - FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Retrieval of developmental social memories requires activation of the adult-born granule cell-CA2 circuit in mice - bioRxiv
CaBLAM! A high-contrast bioluminescent Ca2+indicator derived from an engineeredOplophorus gracilirostrisluciferase - bioRxiv
Dock2 generates characteristic spatiotemporal patterns of Rac activity to regulate neutrophil polarisation, migration and phagocytosis - Frontiers in Immunology
Maternal glucose intolerance during pregnancy affects offspring POMC expression and results in adult metabolic alterations in a sex-dependent manner - Frontiers in endocrinology
Vasodilators activate TMEM16A channels in endothelial cells to reduce blood pressure - bioRxiv : the preprint server for biology
Novel Immune Responses in Lung Injury and Fibrosis - Thesis
The MHC-E Peptide Ligand of Checkpoint NKG2A Is Governed by Inflammatory Signals and High Turnover - papers.ssrn.com
A crystallin mutant cataract with mineral deposits - The Journal of biological chemistry
Astrocyte-oligodendrocyte interaction regulates central nervous system regeneration - Nature Communications
Optimisation of sample preparation from primary mouse tissue to maintain RNA integrity for methods examining translational control - bioRxiv
A cre driver line for genetic targeting of kappa opioid receptor expressing cells - eNeuro
Sodium appetite and thirst do not require angiotensinogen production in astrocytes or hepatocytes - The Journal of Physiology
Autophagy Dysfunction in Parkinson's Disease and Related Synucleinopathies - Thesis
Context-specific GITR agonism potentiates anti-PD-L1 and CD40-based immuno-chemotherapy combination in heterogeneous pancreatic tumors - bioRxiv
Modeling Congenital Heart Disease in Mice and Assessing its Effects on Fetal Brain Development - Thesis
Contribution of macrophages to intracochlear tissue remodeling responses following cochlear implantation and neural survival - Research Square
Behavioral Sex Differences Caused by Distinct Vasopressin Sources - Thesis
Longitudinal analysis of a dietary mouse model of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) - bioRxiv : the preprint server for biology
Enteric glial hub cells coordinate intestinal motility - bioRxiv : the preprint server for biology
TMEM106B Puncta Is Increased in Multiple Sclerosis Plaques, and Reduced Protein in Mice Results in Delayed Lipid Clearance Following CNS Injury - Cells
Biochemical, biomarker, and behavioral characterization of theGrnR493Xmouse model of frontotemporal dementia - bioRxiv
Epsilon tubulin is an essential determinant of microtubule-based structures in male germ cells - bioRxiv
Cation flux through SUR1-TRPM4 and NCX1 in astrocyte endfeet induces water influx through AQP4 and brain swelling after ischemic stroke - Science Signaling
DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner - PLoS Biology
Improvement of retinal function in Alzheimer disease-associated retinopathy by dietary lysophosphatidylcholine-EPA/DHA - Scientific Reports
Spontaneous allelic variant in deafness-blindness gene Ush1g resulting in an expanded phenotype - Genes, brain, and behavior
AS160 expression, but not AS160 Serine-588, Threonine-642, and Serine-704 phosphorylation, is essential for elevated insulin-stimulated glucose uptake by skeletal muscle from female rats after acute exercise - FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Triplication of the interferon receptor locus contributes to hallmarks of Down syndrome in a mouse model - Nature genetics
Chromophore supply modulates cone function and survival in retinitis pigmentosa mouse models - Proceedings of the National Academy of Sciences of the United States of America
Unraveling the Mechano-Molecular Mechanisms of TRAP Activity Using CRISPR/Cas9 Mediated Fluorescent Reporter Mice - Available at SSRN
Neuronal Tau Pathology Worsens Late Phase White Matter Degeneration After Traumatic Brain Injury in Transgenic Mice - bioRxiv
Kit Ligand and Kit receptor tyrosine kinase sustain synaptic inhibition of Purkinje Cells - bioRxiv
Hardwiring tissue-specific AAV transduction in mice through engineered receptor expression - Nature Methods
Immune cell identity behind the Ktrans mapping of mouse glioblastoma - Magnetic resonance imaging
Identification of age-specific gene regulators of La Crosse virus neuroinvasion and pathogenesis - Nature Communications
Contrasting synaptic roles of MDGA1 and MDGA2 - bioRxiv
Deficiency of miR-409-3p improves myocardial neovascularization and function through modulation of DNAJB9/p38 MAPK signaling - Molecular Therapy - Nucleic Acids
In vivo screening of tumor-hepatocyte interactions identifies Plexin B2 as a gatekeeper of liver metastasis - bioRxiv
Complex synaptic and intrinsic interactions disrupt input/output functions in the hippocampus of Scn1b knockout mice - bioRxiv : the preprint server for biology
HNF4α mediated QPRT expression in the kidney facilitates resilience against acute kidney injury - bioRxiv
Cerebellar structural, astrocytic, and neuronal abnormalities in the SMNΔ7 mouse model of spinal muscular atrophy - Brain pathology (Zurich, Switzerland)
Dissecting the functional organization of the C. elegans serotonergic system at whole-brain scale - Cell
Acute stressors do not impair short-term memory or attention in an aged mouse model of amyloidosis - Frontiers in Behavioral Neuroscience
Modulation of TRPV4 protects against degeneration induced by sustained loading and promotes matrix synthesis in the intervertebral disc - FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Platelet-derived chemokines promote skeletal muscle regeneration by guiding neutrophil recruitment to injured muscles - Nature Communications
Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease - Journal of visualized experiments : JoVE
Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis - Elife
Alcohol and Ganaxolone Suppress Tremor via Extra-Synaptic GABAA Receptors in the Harmaline Model of Essential Tremor - Tremor and other hyperkinetic movements (New York, N.Y.)
Transfusion with Blood Plasma from Young Mice Affects rTg4510 Transgenic Tau Mice Modeling of Alzheimer’s Disease - Brain Sciences
Age-associated features of norovirus infection analysed in mice - Nature Microbiology
Calcium Dynamics of the Ventrolateral Preoptic GABAergic Neurons during Spontaneous Sleep-Waking and in Response to Homeostatic Sleep Demands - International Journal of Molecular Sciences
Intrinsic suppression of type I interferon production underlies the therapeutic efficacy of IL-15-producing natural killer cells in B-cell acute lymphoblastic leukemia - Journal for immunotherapy of cancer
Mouse all-cone retina models of Cav1.4 synaptopathy - Frontiers in Molecular Neuroscience
Sphingomyelin d18:1/14:0 activates TLR4 in metaflammation - Research Square
eIF2B Activator Rescues Neonatal Lethality of an eIF2Bα Sugar Phosphate Binding Mutation Associated with Vanishing White Matter Disease - bioRxiv
BQ788 Reveals Glial ETBR Modulation of Neuronal Cholinergic and Nitrergic Pathways to Inhibit Intestinal Motility: ETBR Signaling is Linked to POI - British journal of pharmacology
Type I interferon response in astrocytes promotes brain metastasis by enhancing monocytic myeloid cell recruitment - Nature Communications
Skeletal muscle delimited myopathy and verapamil toxicity in SUR2 mutant mouse models of AIMS - EMBO Molecular Medicine
Genetic deletion of the inflammation-regulated microRNA miR-146a increases exon-skipping mediated dystrophin restoration in Duchenne muscular dystrophy - bioRxiv : the preprint server for biology
Sympathetic tone dictates the impact of lipolysis on FABP4 secretion - Journal of Lipid Research
Duchenne muscular dystrophy disease severity impacts skeletal muscle progenitor cells systemic delivery - Frontiers in Physiology
Brain cell type specific proteomics approach to discover pathological mechanisms in the childhood CNS disorder mucolipidosis type IV - bioRxiv
Protocol to establish a genetically engineered mouse model of IDH1-mutant astrocytoma - STAR Protocols
Retinal alpha-synuclein accumulation correlates with retinal dysfunction and structural thinning in the A53T mouse model of Parkinson's disease - Frontiers in Neuroscience
Progressive generalized tonic-clonic seizures in a transgenic mouse model of adult-onset epilepsy: implications for morphological changes in cortico-limbic and brainstem structures - Epilepsy Research
β2 nAChR Activation on VTA DA Neurons Is Sufficient for Nicotine Reinforcement in Rats - eNeuro
Group I metabotropic glutamate receptor-triggered temporally patterned action potential-dependent spontaneous synaptic transmission in mouse MNTB neurons - Hearing Research
Exploring Dopamine Receptor Pharmacology Through Signaling Bias and Brain Expression - Thesis
Proteolytic processing of galectin-3 by meprin metalloproteases is crucial for host-microbiome homeostasis - Science advances
Reversal of cell, circuit and seizure phenotypes in a mouse model ofDNM1epileptic encephalopathy - bioRxiv
Collaborative Cross strains reveal thatIrf3deficiency results in uncontrolled Zika virus replicationin vitrobut is insufficient to induce disease susceptibility in mice - bioRxiv
Quantitative analysis of vestibular pathways and behavior in mice: implications for understanding basic physiology and disease - Thesis
Vesicle-associated membrane protein 2 is a cargo-selective v-SNARE for a subset of GPCRs - The Journal of cell biology
Monocyte depletion enhances neutrophil influx and proneural to mesenchymal transition in glioblastoma - Nature Communications
Intestinal transit amplifying cells require METTL3 for growth factor signaling, KRAS expression, and cell survival - bioRxiv : the preprint server for biology
Maintenance of a short-lived protein required for long-term memory involves cycles of transcription and local translation - Neuron
Lymphatic Contractile Dysfunction in Mouse Models of Cantú Syndrome with Katp Channel Gain-Of-Function - Function
A synaptic molecular dependency network in knockdown of autism- and schizophrenia-associated genes revealed by multiplexed imaging - Cell Reports
SARM1 detection in myelinating glia: sarm1/Sarm1 is dispensable for PNS and CNS myelination in zebrafish and mice - Frontiers in Cellular Neuroscience
Full-length optic nerve regeneration in the absence of genetic manipulations - JCI Insight
Polycomb Ezh1 maintains murine muscle stem cell quiescence through non-canonical regulation of Notch signaling - Developmental Cell
Prefrontal PV interneurons facilitate attention and are linked to attentional dysfunction in a mouse model of absence epilepsy - Elife
Microglial-to-neuronal CCR5 signaling regulates autophagy in neurodegeneration - Neuron
Retinopathy of prematurity protection conferred by uteroplacental insufficiency through erythropoietin signaling in an experimental Murine Model - Pediatric research
Optogenetic-Induced Muscle Loading Leads to Mechanical Adaptation of the Achilles Tendon Enthesis in Mice - bioRxiv : the preprint server for biology
UNILATERAL, DAILY BOUTS OF MUSCLE LOADING LEADS TO MINERAL AND EXTRACELLULAR ADAPTATION OF THE IMMATURE ACHILLES ENTHESIS IN MICE - par.nsf.gov
Sleep deprivation in obesogenic setting alters lipidome and microbiome toward suboptimal inflammation in acute heart failure - FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Integrin β3 regulates apical dendritic morphology of pyramidal neurons throughout hippocampal CA3 - Hippocampus
Inhibition of Amyloid Beta Oligomer Formation, Binding, and Downstream Tau Phosphorylation: Three Potential Therapeutic Approaches for Alzheimer's Disease - Thesis
Integrative genetic analysis identifies FLVCR1 as a plasma-membrane choline transporter in mammals - Cell Metabolism
The unconditioned fear response in dystrophin-deficient mice is associated with adrenal and vascular function - Scientific Reports
Genetic and Molecular Quality Control of Genetically Engineered Mice - Methods in molecular biology (Clifton, N.J.)
USP7 controls NGN3 stability and pancreatic endocrine lineage development - Nature Communications
A transthalamic pathway is crucial for stimulus feature selectivity in higher order cortex - bioRxiv : the preprint server for biology
Filter exchange imaging with crusher gradient modelling detects increased blood-brain barrier water permeability in response to mild lung infection - Fluids and barriers of the CNS
Sex-specific effects of CD248 on metabolism and the adipose tissue lipidome - PLOS ONE
Deletion of PTEN in microglia ameliorates chronic neuroinflammation following repetitive mTBI - Molecular and cellular neurosciences
Arc Regulates a Second-Guessing Cognitive Bias During Naturalistic Foraging Through Effects on Discrete Behavior Modules - iScience
SaLSa: a combinatory approach of semi-automatic labeling and long short-term memory to classify behavioral syllables - bioRxiv
Late gene therapy limits the restoration of retinal function in a mouse model of retinitis pigmentosa - bioRxiv : the preprint server for biology
Sex and estrous cycle affect experience-dependent plasticity in mouse primary visual cortex - PLOS ONE
Melanocortin 4 receptor signaling in Sim1 neurons permits sexual receptivity in female mice - Frontiers in endocrinology
The Effects of Antipsychotics in Experimental Models of Krabbe Disease - Biomedicines
Longitudinal assessment of cognitive function in the APPswe/PS1dE9 mouse model of Alzheimer's-related beta-amyloidosis - Neurobiology of Aging
Single Systemic Administration of a Gene Therapy Leading to Disease Treatment in Metachromatic Leukodystrophy Arsa Knockout Mice - The Journal of neuroscience : the official journal of the Society for Neuroscience
Mitochondrial abundance and function in the serotonin transporter knockout model: a sexually dimorphic association - Open Access Te Herenga Waka-Victoria University of Wellington
Optogenetics reveals paradoxical network stabilizations in hippocampal CA1 and CA3 - Current biology : CB
Developmental Expression of the Sturge-Weber Syndrome-associated Genetic Mutation in Gnaq: a Formal Test of Happle's Paradominant Inheritance Hypothesis - Genetics
Control of contextual memory through interneuronal α5-GABAA receptors - PNAS nexus
Changes in Memory, Sedation, and Receptor Kinetics Imparted by the β2-N265M and β3-N265M GABAA Receptor Point Mutations - International Journal of Molecular Sciences
35th International Mammalian Genome Conference: meeting overview - Mammalian genome : official journal of the International Mammalian Genome Society
Ablation of Pigment Epithelium-derived Factor Receptor (PEDF-R/Pnpla2) Causes Photoreceptor Degeneration - Journal of Lipid Research
Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2 - Cells
Metabolic correlates to critical speed in murine models of sickle cell disease - Frontiers in Physiology
Cystic Fibrosis Reprograms Airway Epithelial IL-33 Release and Licenses IL-33 Dependent Inflammation - American journal of respiratory and critical care medicine
Activation of the CA2-ventral CA1 pathway reverses social discrimination dysfunction in Shank3B knockout mice - Nature Communications
Stimulator of interferon genes ( STING ) expression in the enteric nervous system and contributions of glial STING in disease - Neurogastroenterology & Motility
Transcriptomic changes predict metabolic alterations in LC3 associated phagocytosis in aged mice - bioRxiv : the preprint server for biology
Investigating the physiological functions of free fatty acid receptor 4 in the lung and colon following synthetic agonist activation - Thesis
p38MAPKa stromal reprogramming sensitizes metastatic breast cancer to immunotherapy - Cancer discovery
Single-cell multiomic analysis reveals the involvement of Type I interferon-responsive CD8+ T cells in amyloid beta-associated memory loss - bioRxiv
Regulation of Prostate Androgens by Megalin and 25-hydroxyvitamin D Status: Mechanism for High Prostate Androgens in African American Men - Cancer research communications
STAT3 Drives GFAP Accumulation and Astrocyte Pathology in a Mouse Model of Alexander Disease - Cells
“Tumor Explants Elucidate a Cascade of Paracrine SHH, WNT, and VEGF Signals Driving Pancreatic Cancer Angiosuppression” - bioRxiv
CEP76 is a critical regulator of male germ cell transition zone function and tail composition - bioRxiv
Farnesoid X receptor agonism prevents neutrophil extracellular traps via reduced sphingosine-1-phosphate in chronic kidney disease - bioRxiv
Distinct in vitro and in vivo neutralization profiles of monoclonal antibodies elicited by the receptor binding domain of the ancestral SARS-CoV-2 - Journal of medical virology
Z-Endoxifen prevents aggressive mammary cancers in mice by inhibiting cell proliferation and creating a tumor suppressive microenvironment - Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Pendrin abundance, subcellular distribution, and function are unaffected by either αENaC gene ablation or by increasing ENaC channel activity - Pflugers Archiv : European journal of physiology
Unravelling specific diet and gut microbial contributions to inflammatory bowel disease - Research Square
Rab46: a novel player in mast cell function - bioRxiv
Neuromodulator recruitment during listening and learning in mice and humans - Thesis
Inactivation of phosphodiesterase-4B gene in rat nucleus accumbens shell by CRISPR/Cas9 modulates the motivation to chronically self-administer nicotine - bioRxiv
Mechanism of KMT5B haploinsufficiency in neurodevelopment in humans and mice - Science advances
How stra(i)nge are your controls? A comparative analysis of metabolic phenotypes in commonly used C57 substrains - bioRxiv
Genetic dissection of triplicated Hsa21 orthologs produces differential skeletal phenotypes in Down syndrome mouse models - Disease Models & Mechanisms
Targeting nonsense-mediated RNA decay does not increase progranulin levels in the Grn R493X mouse model of frontotemporal dementia - PLOS ONE
Sex chromosome and gonadal hormone contributions to binge-like and aversion-resistant ethanol drinking behaviors in Four Core Genotypes mice - Frontiers in Psychiatry
Therapeutic effect of human ApoA-I-Milano variant in aged transgenic mouse model of Alzheimer's disease - British journal of pharmacology
Investigating the tumour suppressor function of RUNX1 in breast cancer - Thesis
Fate-mapping lymphocyte clones and their progenies from induced antigen-signals identifies temporospatial behaviours of T cells mediating tolerance - bioRxiv
Prestin's fast motor kinetics is essential for mammalian cochlear amplification - Proceedings of the National Academy of Sciences of the United States of America
Determining the neuronal ensembles underlying sex-specific social impairments following adolescent intermittent ethanol exposure - bioRxiv : the preprint server for biology
Plasmin and plasminogen prevent sepsis severity by reducing neutrophil extracellular traps and systemic inflammation - JCI Insight
Partial or complete loss of norepinephrine differentially alters contextual fear and catecholamine release dynamics in hippocampal CA1 - bioRxiv
PPARα and PPARγ are expressed in midbrain dopamine neurons and modulate dopamine- and cannabinoid-mediated behavior in mice - Research Square
Surfactant protein A alters endosomal trafficking of influenza A virus in macrophages - Frontiers in Immunology
TRIM28 promotes luminal cell plasticity in a mouse model of prostate cancer - Oncogene
Heparan sulfate promotes ACE2 super-cluster assembly to enhance SARS-CoV-2-associated syncytium formation - Research Square
Light-Guided Rabies Virus Tracing for Neural Circuit Analysis - bioRxiv
Oncogenic RAS promotes leukemic transformation of CUX1-deficient cells - Oncogene
Chronic BMAA exposure combined with TDP-43 mutation elicits motor neuron dysfunction phenotypes in mice - Neurobiology of Aging
Efficient megakaryopoiesis and platelet production require phospholipid remodeling and PUFA uptake through CD36 - bioRxiv : the preprint server for biology
Cholinergic collaterals arising from noradrenergic sympathetic neurons in mice - The Journal of Physiology
m 6 A RNA methylation orchestrates transcriptional dormancy during developmental pausing - bioRxiv : the preprint server for biology
iCre recombinase expressed in the anti-Müllerian hormone receptor 2 gene causes global genetic modification in the mouse - Biology of reproduction
CD11c+ macrophages are pro-angiogenic and necessary for experimental choroidal neovascularization - JCI Insight
hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung's disease - Cell Stem Cell
Delay modulates the immune response to nerve repair - NPJ Regenerative medicine
Neuroimmune interactions with binge alcohol drinking in the cerebellum of IL-6 transgenic mice - Neuropharmacology
Simultaneous 3D cellular positioning and apical dendritic morphology of transgenic fluorescent mouse CA3 hippocampal pyramidal neurons - Journal of Neuroscience Methods
Mechanistic Analysis of CCP1 in Generating ΔC2 α-Tubulin in Mammalian Cells and Photoreceptor Neurons - Biomolecules
The Neuropathological Effects of Zinc and Copper Supplementation on a Dual Transgenic (hAPP/htau) Mouse Model of Alzheimer's Disease - Thesis
CX3CR1+ Macrophage Facilitates the Resolution of Allergic Lung Inflammation via Interacting CCL26 - American journal of respiratory and critical care medicine
Tregs constrain CD8 + T cell priming required for curative intratumorally anchored anti-4-1BB immunotherapy - bioRxiv : the preprint server for biology
RAB7 deficiency impairs pulmonary artery endothelial function and promotes pulmonary hypertension - bioRxiv : the preprint server for biology
UNRAVELing the synergistic effects of psilocybin and environment on brain-wide immediate early gene expression in mice - bioRxiv : the preprint server for biology
Selective deletion of Methyl CpG binding protein 2 from parvalbumin interneurons in the auditory cortex delays the onset of maternal retrieval in mice - bioRxiv : the preprint server for biology
Antipsychotics Prevent Psychosine Induced Toxicity in Glial Cells - Thesis
Lung injury induces a polarized immune response by self antigen-specific Foxp3 + regulatory T cells - bioRxiv : the preprint server for biology
High fat diet ameliorates the mitochondrial cardiomyopathy of CHCHD10 mutant mice - bioRxiv : the preprint server for biology
Neuronal Transcriptome Disruption, Tau Accumulation and Synapse Loss in Alzheimer’s Knock-in Mice Require Cellular Prion Protein - bioRxiv
Palmitoyl transferase ZDHHC20 promotes pancreatic cancer metastasis - bioRxiv
The parabrachial to central amygdala circuit is a key mediator of injury-induced pain sensitization - bioRxiv
PI5P4Kα supports prostate cancer metabolism and exposes a survival vulnerability during androgen receptor inhibition - Science advances
Gamma-patterned sensory stimulation reverses synaptic plasticity deficits in rat models of early Alzheimer's disease - AUTHOREA
Impaired polyamine metabolism causes behavioral and neuroanatomical defects in a novel mouse model of Snyder-Robinson Syndrome - bioRxiv : the preprint server for biology
Deletion of the Transcriptional Coactivator HCF-1 In Vivo Impairs the Removal of Repressive Heterochromatin from Latent HSV Genomes and Suppresses the Initiation of Viral Reactivation - mBio
Low protease activity in B cell follicles promotes retention of intact antigens after immunization - Science (New York, N.Y.)
The cytoplasmic localization of ADNP through 14-3-3 promotes sex-dependent neuronal morphogenesis, cortical connectivity, and calcium signaling - Molecular Psychiatry
A p53-TLR3 axis ameliorates pulmonary hypertension by inducing BMPR2 via IRF3 - iScience
Gene Therapy to Treat Osteopenia Associated with Chronic Ethanol Consumption and Aldehyde Dehydrogenase 2 Deficiency - JBMR Plus
Microglial heterogeneity and complement component 3 elimination within emerging multisensory midbrain compartments during an early critical period - Frontiers in Neuroscience
YAP and TAZ couple osteoblast precursor mobilization to angiogenesis and mechanoregulated bone development - bioRxiv : the preprint server for biology
Chemical flavorants in vaping products alter neurobiology in a sex-dependent manner to promote vaping-related behaviors - The Journal of neuroscience : the official journal of the Society for Neuroscience
Adrenal-specific KO of the circadian clock protein BMAL1 alters blood pressure rhythm and timing of eating behavior - Function
The rates of adult neurogenesis and oligodendrogenesis are linked to cell cycle regulation through p27-dependent gene repression of SOX2 - Cellular and molecular life sciences : CMLS
Low nephron endowment increases susceptibility to renal stress and chronic kidney disease - JCI Insight
Sex-dependent differences in mouse placental gene expression following a maternal high fat diet - American journal of perinatology
Cannabinoid CB1 Receptors Are Expressed in a Subset of Dopamine Neurons and Underlie Cannabinoid-Induced Aversion, Hypoactivity, and Anxiolytic Effects in Mice - The Journal of neuroscience : the official journal of the Society for Neuroscience
A novel mechanism for T1R-independent taste responses to concentrated sugars - The Journal of neuroscience : the official journal of the Society for Neuroscience
Telomerase reactivation induces progression of mouse BrafV600E-driven thyroid cancers without telomere lengthening - bioRxiv
LY6E protects mice from pathogenic effects of murine coronavirus and SARS-CoV-2 - bioRxiv
Notch Signaling Suppresses Melanoma Tumor Development in BRAF/Pten Mice - Cancers
BTG1 mutation yields supercompetitive B cells primed for malignant transformation - Science (New York, N.Y.)
Acss2 Deletion Reveals Functional Versatility via Tissue-Specific Roles in Transcriptional Regulation - Preprint
Functional integrity of visual coding following advanced photoreceptor degeneration - Current biology : CB
Transient Receptor Potential Ankyrin-1-expressing vagus nerve fibers mediate IL-1β induced hypothermia and reflex anti-inflammatory responses - Molecular medicine (Cambridge, Mass.)
ARPC5 deficiency leads to severe early onset systemic inflammation and early mortality - bioRxiv
ChAT::Cre transgenic rats show sex-dependent altered fear behaviors, ultrasonic vocalizations and cholinergic marker expression - Genes, brain, and behavior
Molecular Identity Changes of Tumor-Associated Macrophages and Microglia After Magnetic Resonance Imaging-Guided Focused Ultrasound-Induced Blood-Brain Barrier Opening in a Mouse Glioblastoma Model - Ultrasound in medicine & biology
Conditional deletion of CD25 in the corneal epithelium reveals sex differences in barrier disruption - The ocular surface
Analytical Approaches for Complex Multi-Batch-Omics Datasets and Their Application to Neuronal Development - Thesis
Low ceruloplasmin levels exacerbate retinal degeneration in a hereditary hemochromatosis model - Disease Models & Mechanisms
Phenotypic characterisation of the Mucopolysaccharidosis Type I (MPSI) Idua-W392X mouse model reveals increased anxiety-related traits in female mice - Molecular genetics and metabolism
Beating heart cells: Using cultured cardiomyocytes to study cellular structure and contractility in laboratory exercises - Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology
Impact of Maternal Hyperglycemia and Maternal Antenatal Stress on the Number of POMC Neurons in the ARC of Male and Female Rats Prior to Birth - Carleton University
RotaRod and acoustic startle reflex performance of two potential mouse models for Meniere's disease - The European journal of neuroscience
Mycoplasma DnaK increases DNA copy number variants in vivo - Proceedings of the National Academy of Sciences of the United States of America
Combination-Based Drug Screening for Induced Oligodendrocyte Differentiation Enables Mechanistic Insight and Identifies Optimal Drug Pairs for Remyelination - bioRxiv
Oscillatory-Quality of sleep spindles: from properties to function - bioRxiv
Xrcc5/Ku80 is required for the repair of DNA damage in fully grown meiotically arrested mammalian oocytes - Cell death & disease
Region-specific reversal of epidermal planar polarity in the fancyrosettemouse - bioRxiv
Optical Imaging Reveals Liver Metabolic Perturbations in Mblac1 Knockout Mice - arinex.com.au
The Role of Decorin and Biglycan in CNS Angiogenesis and EAE Recovery - Thesis
Synthetic GM1 improves motor and memory dysfunctions in mice with monoallelic or biallelic disruption of GM3 synthase - FEBS open bio
Phenotypic screen-based discovery of a small molecule that can increase adult neurogenesis and improve memory - bioRxiv
Vhl deletion inDmp1-expressing cells alters MEP metabolism and promotes stress erythropoiesis - bioRxiv
Matrix metalloproteinase-9 regulates afferent arteriolar remodeling and function in hypertension-induced kidney disease - Kidney International
Multidimensional definition of the interferonopathy of Down syndrome and its response to JAK inhibition - Science advances
Expression of a STING Gain-of-function Mutation in Endothelial Cells Initiates Lymphocytic Infiltration of the Lungs - bioRxiv
Activation of Autoreactive Lymphocytes in the Lung by STING Gain-of-function Mutation Radioresistant Cells - bioRxiv
Microglial Nogo delays recovery following traumatic brain injury in mice - Glia
Chromatin architectural factor CTCF is essential for progesterone-dependent uterine maturation - FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Signals of Physiological Status Modulate Food-and Food-Cue-Driven Activity of Dopamine Neurons - Thesis
Telomerase upregulation induces progression of mouse BrafV600E-driven thyroid cancers and triggers non-telomeric effects - Molecular cancer research : MCR
Both intratumoral regulatory T cell depletion and CTLA-4 antagonism are required for maximum efficacy of anti-CTLA-4 antibodies - Proceedings of the National Academy of Sciences of the United States of America
PIEZO1 force sensing controls global lipid homeostasis - bioRxiv
Moderate hypoxia induces metabolic divergence in circulating monocytes and tissue resident macrophages from Berkeley sickle cell anemia mice - Frontiers in medicine
Human TLR8 induces inflammatory bone marrow erythromyeloblastic islands and anemia in SLE-prone mice - Life science alliance
LY6E is a pan-coronavirus restriction factor in the respiratory tract - Nature Microbiology
AAV5-mediated manipulation of insulin expression in choroid plexus has long-term metabolic and behavioral consequences - Cell Reports
Susceptibility to Cryptococcus neoformans Infection with Bruton's Tyrosine Kinase Inhibition - Infection and Immunity
CSTB gene replacement improves neuroinflammation, neurodegeneration and ataxia in murine Type 1 Progressive Myoclonus Epilepsy - Research Square
Movement-related modulation in mouse auditory cortex is widespread yet locally diverse - bioRxiv : the preprint server for biology
Using Live Cell STED Imaging to Visualize Mitochondrial Inner Membrane Ultrastructure in Neuronal Cell Models - Journal of visualized experiments : JoVE
IGFBPL1 is a master driver of microglia homeostasis and resolution of neuroinflammation in glaucoma and brain tauopathy - Cell Reports
Sex differences in afferents and efferents of vasopressin neurons of the bed nucleus of the stria terminalis and medial amygdala in mice - Hormones and Behavior
Lrp1 is essential for lethal Rift Valley fever hepatic disease in mice - Science advances
Lung injury induces a polarized immune response by self-antigen-specific CD4+ Foxp3+ regulatory T cells - Cell Reports
The lncRNA HOXA11os regulates mitochondrial function in myeloid cells to maintain intestinal homeostasis - Cell Metabolism
ARPC5 deficiency leads to severe early-onset systemic inflammation and mortality - Disease Models & Mechanisms
Role of Neural Activity and Perineuronal Nets in Adolescent Intermittent Ethanol-Induced Social Anxiety - Thesis
Differential roles of FOXC2 in the trabecular meshwork and Schlemm's canal in glaucomatous pathology - Life science alliance
Low-molecular weight sulfated marine polysaccharides: Promising molecules to prevent neurodegeneration in mucopolysaccharidosis IIIA? - Carbohydrate Polymers
Overexpression of Nfe2l1 increases proteasome activity and delays vision loss in a preclinical model of human blindness - Science advances
Human Plasma Proteomic Profile of Clonal Hematopoiesis - bioRxiv
Investigating a New Drug Target in Alzheimer's Disease: NOX2 - Thesis
FOXC1 regulates endothelial CD98 (LAT1/4F2hc) expression in retinal angiogenesis and blood-retina barrier formation - Nature Communications
The Peripheral Mechanisms of Musculoskeletal Pain - Thesis
lncRNA ADEPTR loss-of-function elicits sex-specific behavioral and spine deficits - bioRxiv
RNAseq analysis reveals transcriptome changes associated with the progression of non-alcoholic liver disease in livers fromEfcab4bknockout mice - bioRxiv
The aged tumor microenvironment limits T cell control of cancer - Nature Immunology
Investigating brain network deficits in a rodent schizophrenia model - Thesis
"Tumor-selective treatment of metastatic pancreatic cancer with an engineered, probiotic living drug" - bioRxiv : the preprint server for biology
Pervasive nuclear envelope ruptures precede ECM signaling and disease onset without activating cGAS-STING in Lamin-cardiomyopathy mice - bioRxiv : the preprint server for biology
Dynamic changes in mitochondria support phenotypic flexibility of microglia - bioRxiv
Induction of tauopathy in a mouse model of amyloidosis using intravenous administration of adeno-associated virus vectors expressing human P301L tau - Alzheimer's & dementia (New York, N. Y.)
Detecting the effect of genetic diversity on brain composition in an Alzheimer's disease mouse model - Communications Biology
A cell type-specific approach to elucidate the role of miR-96 in inner ear hair cells - Frontiers in Audiology and Otology
Innervation of Adipocytes is Limited in Mouse Perivascular Adipose Tissue - American journal of physiology. Heart and circulatory physiology
Human IL-6 fosters long-term engraftment of patient-derived disease-driving myeloma cells in immunodeficient mice - JCI Insight
Microbiome-driven alterations in metabolic pathways and impaired cognition in aged female TgF344-AD rats - Aging Brain
Optimisation of animal handing and timing of 2-deoxy-2-[18F]fluoro-D-glucose PET tumour imaging in mice - Research Square
Matriglycan maintains t-tubule structural integrity in cardiac muscle - Proceedings of the National Academy of Sciences of the United States of America
SLAMseq reveals transfer of RNA from liver to kidney in the mouse - bioRxiv
Characterization of sleep in a mouse model of CLN3 disease revealed sex-specific sleep disturbances - bioRxiv
MT-125 Inhibits Non-Muscle Myosin IIA and IIB, Synergizes with Oncogenic Kinase Inhibitors, and Prolongs Survival in Glioblastoma - bioRxiv : the preprint server for biology
Tumor immunogenicity regulates host immune responses, and conventional dendritic cell type 2 uptakes the majority of tumor antigens in an orthotopic lung cancer model.  - Research Square
Aging-Induced Semaphorin 7a Promotes Tgfβ1-Mediated Cell Plasticity and Breast Tumor Metastases - Available at SSRN 
The role of mu-opioid receptors in pancreatic islet alpha cells - bioRxiv : the preprint server for biology
STAT5B SH2 variants disrupt mammary enhancers and the stability of genetic programs during pregnancy - bioRxiv
Airway hillocks are injury-resistant reservoirs of unique plastic stem cells - Nature
Deletion of Hsd11b1 suppresses caloric-restriction-induced bone marrow adiposity in male but not female mice - The Journal of endocrinology
Behavioral and Molecular Changes Following Acute Sleep Deprivation in Juvenile Wild-Type and Shank3WT/ΔC Mice - Thesis
Caspase-resistant ROCK1 expression prolongs survival of Eµ-Myc B cell lymphoma mice - Disease Models & Mechanisms
Ciliary tip actin dynamics regulate photoreceptor outer segment integrity - Nature Communications
Lack of evidence for GWAS signals of exfoliation glaucoma working via monogenic loss-of-function mutation in the nearest gene - Human Molecular Genetics
Locally Administered Particle-Anchored Cytokines Safely Enhance Cancer Immunotherapy - Thesis
Fetal growth delay caused by loss of non-canonical imprinting is resolved late in pregnancy and culminates in offspring overgrowth - Elife
The glucocorticoid receptor acts locally to protect dystrophic muscle and heart during disease - Disease Models & Mechanisms
Post-transcriptional regulation and subcellular localization of G-protein γ7 subunit: implications for striatal function and behavioral responses to cocaine - Frontiers in Neuroanatomy
Affinity gaps among B cells in germinal centers drive the selection of MPER precursors - Nature Immunology
A vasopressin circuit that modulates mouse social investigation and anxiety-like behavior in a sex-specific manner - Proceedings of the National Academy of Sciences of the United States of America
A blood-brain-barrier penetrant AAV gene therapy improves neurologic function in symptomatic mucolipidosis IV mice. - Molecular Therapy - Methods & Clinical Development
Vaccination induces broadly neutralizing antibody precursors to HIV gp41 - Nature Immunology
BAP1 is required prenatally for differentiation and maintenance of postnatal murine enteric nervous system - The Journal of clinical investigation
Cardiac function is regulated by the sodium-dependent inhibition of the sodium-calcium exchanger NCX1 - Nature Communications
Human striatal progenitor cells that contain inducible safeguards and overexpress BDNF rescue Huntington’s disease phenotypes in R6/2 mice - bioRxiv
Advancing Age and the rs6265 BDNF SNP are Permissive to Graft-induced Dyskinesias in Parkinsonian Rats - Research Square
Astrocytic Ephrin-B1 Controls PV Synapse Formation Through Regulating EphB2 in PV Boutons - Thesis
The frequency dependence of prestin-mediated fast electromotility for mammalian cochlear amplification - bioRxiv : the preprint server for biology
Trisomy 8 Defines a Distinct Subtype of Myeloproliferative Neoplasms Driven by the MYC-Alarmin Axis - Blood cancer discovery
Mitochondria regulate proliferation in adult cardiac myocytes - The Journal of clinical investigation
Differential impact of sex on regulation of skeletal muscle mitochondrial function and protein homeostasis by hypoxia-inducible factor-1α in normoxia - The Journal of Physiology
p53 and TIGAR promote redox control to protect against metabolic dysfunction-associated steatohepatitis - bioRxiv
Outer Hair Cell Motor Protein, Prestin, Is Not a Reliable Serological Biomarker for Mouse Cochlear Damage - Preprint
PGC-1α repression dysregulates lipid metabolism and induces lipid droplet accumulation in retinal pigment epithelium - Cell death & disease
Kidney collecting duct-derived vasopressin is not essential for appropriate concentration or dilution of urine - American journal of physiology. Renal physiology
The inflammatory microenvironment of the lung at the time of infection governs innate control of SARS-CoV-2 replication - bioRxiv : the preprint server for biology
The factor inhibiting HIF regulates T cell differentiation and anti-tumour efficacy - Frontiers in Immunology
GPATCH8 modulates mutant SF3B1 mis-splicing and pathogenicity in hematologic malignancies - Molecular Cell
Osterix-driven LINC complex disruption in vivo diminishes osteogenesis at 8 weeks but not at 15 weeks - Journal of orthopaedic research : official publication of the Orthopaedic Research Society
IL-17RA-Mediated Epithelial Cell Activity Prevents Severe Inflammatory Response to Helicobacter pylori Infection - ImmunoHorizons
Loss of Midbrain Dopamine Neurons Does Not Alter GABAergic Inhibition Mediated by Parvalbumin-Expressing Interneurons in Mouse Primary Motor Cortex - eNeuro
Preclinical Multi-Omic Assessment of Pioglitazone in Skeletal Muscles of Mice Implanted with Human HER2/neu Overexpressing Breast Cancer Xenografts - bioRxiv : the preprint server for biology
Thermal escape box: A cost-benefit evaluation paradigm for investigating thermosensation and thermal pain - Neurobiology of pain (Cambridge, Mass.)
Efficient spectral tests for multiple recursive generators - Communications in Statistics - Theory and Methods
Ciliopathy patient variants reveal organelle-specific functions for TUBB4B in axonemal microtubules - Science (New York, N.Y.)
Multi-scale in vivo imaging of tumour development using a germline conditional triple-reporter system - Research Square
Overexpression of soluble epoxide hydrolase reduces post-ischemic recovery of cardiac contractile function - Biochemical pharmacology
Endothelial cell expression of a STING gain-of-function mutation initiates pulmonary lymphocytic infiltration - Cell Reports
WNK kinase is a vasoactive chloride sensor in endothelial cells - Proceedings of the National Academy of Sciences of the United States of America
Addition of low sodium does not increase sensitivity to glucose in wild-type mice, or lead to partial glucose taste detection in T1R3 knock-out mice - Physiology & behavior
A Role for GABAA Receptor β3 Subunits in Mediating Harmaline Tremor Suppression by Alcohol: Implications for Essential Tremor Therapy - Tremor and other hyperkinetic movements (New York, N.Y.)
The structural and functional integrity of rod photoreceptor ribbon synapses depends on redundant actions of dynamins 1 and 3 - The Journal of neuroscience : the official journal of the Society for Neuroscience
Fine Mapping and Candidate Gene Analysis of Dravet Syndrome Modifier Loci on Mouse Chromosomes 7 and 8 - bioRxiv : the preprint server for biology
Genetic mutation of Cep76 results in male infertility due to abnormal sperm tail composition - Life science alliance
Variant-specific in vitro neuronal network phenotypes and drug sensitivity in SCN2A developmental and epileptic encephalopathy - Journal of neurochemistry
Inconsequential role for chemerin-like receptor 1 in the manifestation of ozone-induced lung pathophysiology in male mice - Physiological Reports
Phenotypic analysis of multielectrode array EEG biomarkers in developing and adult male Fmr1 KO mice - Neurobiology of Disease
A glycolytic metabolite bypasses "two-hit" tumor suppression by BRCA2 - Cell
Adam19 Deficiency Impacts Pulmonary Function: Human GWAS Follow-up in Mouse - Research Square
Seeding competent TDP-43 persists in human patient and mouse muscle - bioRxiv : the preprint server for biology
Two contrasting mediodorsal thalamic circuits target the mouse medial prefrontal cortex - Journal of Neurophysiology
Maternal PFOS exposure affects offspring development in Nrf2-dependent and independent ways in zebrafish (Danio rerio) - Aquatic toxicology (Amsterdam, Netherlands)
Thermotherapy has Sexually Dimorphic Responses in APP/PS1 Mice - bioRxiv : the preprint server for biology
Mesenchymal-specific Alms1 knockout in mice recapitulates metabolic features of Alström syndrome - Molecular Metabolism
G α olf Regulates Biochemical Signaling in Neurons Associated with Movement Control and Initiation - bioRxiv : the preprint server for biology
Tissue adaptations to colitis influence neoplastic risk through clonal interaction - Thesis
Characterization of a Novel Mouse Model for Fuchs Endothelial Corneal Dystrophy - Investigative ophthalmology & visual science
RNA Profiling of Brain Microvessels Reveals Altered Morphology and Signaling in a Mouse Model of Alzheimer's Disease - Research Square
Noncovalently particle-anchored cytokines with prolonged tumor retention safely elicit potent antitumor immunity - Science advances
Female Type 1 Diabetic Akita Mice Demonstrate Increased Bladder Contractility via FP Receptor Activation due to NLRP3-Mediated Inflammation - Frontiers in bioscience (Landmark edition)
Axonal organelle buildup from loss of AP-4 complex function causes exacerbation of amyloid plaque pathology and gliosis in Alzheimer's disease mouse model - bioRxiv : the preprint server for biology
The Effect of Donepezil Hydrochloride in the Twitcher Mouse Model of Krabbe Disease - Molecular Neurobiology
Macrophage-fibroblast JAK/STAT dependent crosstalk promotes liver metastatic outgrowth in pancreatic cancer - Nature Communications
Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses - Immunity
Targeting transitioning lung monocytes/macrophages as treatment strategies in lung disease related to environmental exposures - Respiratory research
γ-Aminobutyric acid transporter and GABAA receptor mechanisms in Slc6a1+/A288V and Slc6a1+/S295L mice associated with developmental and epileptic encephalopathies - Brain Communications
Correlating Stool Deposition and Gut Health Dynamics with Microbial Diversity Alterations - Cureus Journal of Medical Science
Manipulation of α4βδ GABAA receptors alters synaptic pruning in layer 3 prelimbic prefrontal cortex and impairs temporal order recognition: Implications for schizophrenia and autism - Brain Research
The BALB/c.mdx62 mouse exhibits a dystrophic muscle pathology and is a novel model of Duchenne muscular dystrophy - Disease Models & Mechanisms
Chloride/proton antiporters ClC3 and ClC5 support bone formation in mice - Bone Reports
Overcoming Xenoantigen Immunity to Enable Cellular Tracking and Gene Regulation with Immune-competent "NoGlow" Mice - Cancer research communications
Phosphorylation of AS160-Serine 704 is Not Essential for Exercise-increase in Insulin-stimulated Glucose Uptake by Skeletal Muscles from Female or Male Rats - American journal of physiology. Endocrinology and metabolism
Tumor-selective activity of RAS-GTP inhibition in pancreatic cancer - Nature
Long-term follow-up of TREK-1 KO mice reveals the development of bladder hypertrophy and impaired bladder smooth muscle contractility with age - American journal of physiology. Renal physiology
Polyploidisation pleiotropically buffers ageing in hepatocytes - Journal of hepatology
Impaired polyamine metabolism causes behavioral and neuroanatomical defects in a mouse model of Snyder-Robinson Syndrome - Disease Models & Mechanisms
Epigenetic small-molecule screen for inhibition and reversal of acinar ductal metaplasia in mouse pancreatic organoids - Frontiers in pharmacology
Liver-derived plasminogen mediates muscle stem cell expansion during caloric restriction through the plasminogen receptor Plg-RKT - Cell Reports
A humanized mouse model for adeno-associated viral gene therapy - Nature Communications
Ultra-fast genetically encoded sensor for precise real-time monitoring of physiological and pathophysiological peroxide dynamics - Research Square
The Updated Mouse Universal Genotyping Array Bioinformatic Pipeline Improves Genetic QC in Laboratory Mice - bioRxiv : the preprint server for biology
Robust Methods For Quantifying Neuronal Morphology And Molecular Signaling Reveal That Psychedelics Do Not Induce Neuroplasticity - bioRxiv
Knockdown siRNA targeting GPR55 reveals significant differences between the anti-inflammatory actions of KLS-13019 and cannabidiol - Research Square
Targeted Gene Deletion or Antagonism of the Prostaglandin E2 EP3 Receptor Protects Against Cardiac Injury Postmyocardial Infarction - Circulation. Heart failure
Paternal DDT exposure induces sex-specific programming of fetal growth, placenta development and offspring's health phenotypes in a mouse model - Scientific Reports
No significant sex differences in incidence or phenotype for the SMNΔ7 mouse model of spinal muscular atrophy - Neuromuscular disorders : NMD
Senolytic CAR T cells reverse aging-associated defects in intestinal regeneration and fitness - bioRxiv : the preprint server for biology
Adolescent Binge Ethanol Exposure Accelerates Alzheimer's Disease-Associated Basal Forebrain Neuropathology - Thesis
Altered tongue muscle contractile properties coincide with altered swallow function in the adult Ts65Dn mouse model of down syndrome - Frontiers in Neurology
Septo-hypothalamic regulation of binge-like alcohol consumption by the nociceptin system - bioRxiv
The Nonvesicular Sterol Transporter Aster-C Plays a Minor Role in Whole Body Cholesterol Balance - Frontiers in Physiology
Alpha-Synuclein and GM1 Ganglioside Co-Localize in Neuronal Cytosol Leading to Inverse Interaction-Relevance to Parkinson's Disease - International Journal of Molecular Sciences
The TLK-ASF1 histone chaperone pathway plays a critical role in IL-1b-mediated AML progression - Blood
An Amygdalar Oscillator Coordinates Cellular and Behavioral Rhythms - bioRxiv
Caspase-resistant ROCK1 expression prolongs survival ofEµ-MycB cell lymphoma mice - bioRxiv
Effects of age and dietary methionine restriction on cognitive and behavioural phenotypes in the rTg4510 model of frontotemporal dementia - bioRxiv
Computational techniques to interpret the neural code underlying complex cognitive processes - Thesis
Preclinical modelling of altered neuroinflammation and interferon hyper-sensitivity in Alzheimer's disease-Down syndrome - Thesis
Cognitive decline, Aβ pathology, and blood-brain barrier function in aged 5xFAD mice - Fluids and barriers of the CNS
Low intensity repetitive transcranial magnetic stimulation enhances remyelination by newborn and surviving oligodendrocytes in the cuprizone model of toxic demyelination - bioRxiv
Effects of noncanonical genomic imprinting in monoaminergic pathways on the regulation of social behaviors - bioRxiv
CD8+ T cell priming that is required for curative intratumorally anchored anti-4-1BB immunotherapy is constrained by Tregs - Nature Communications
Loss of the APP regulator RHBDL4 preserves memory in an Alzheimer's disease mouse model - bioRxiv : the preprint server for biology
Opposing diet, microbiome, and metabolite mechanisms regulate inflammatory bowel disease in a genetically susceptible host - Cell host & microbe
Light regulation of rhodopsin distribution during outer segment renewal in murine rod photoreceptors - Current biology : CB
Engineering luminopsins with improved coupling efficiencies - Neurophotonics
Altering Adolescent Synaptic Pruning in Layer 3 Prelimbic Prefrontal Cortex via Manipulation of α4βδ GABAA Receptors Impairs Temporal Order Recognition: Implications for Schizophrenia and Autism - Available at SSRN 4739194
Intestinal tuft cell immune privilege enables norovirus persistence - Science Immunology
Targeted irradiation in an autochthonous mouse model of pancreatic cancer - Disease Models & Mechanisms
Patterns of neuronal activation following ethanol-induced social facilitation and social inhibition in adolescent cFos-LacZ male and female rats - bioRxiv
Prelimbic cortex perineuronal net expression and social behavior: Impact of adolescent intermittent ethanol exposure - bioRxiv
SIRT4 loss reprograms intestinal nucleotide metabolism to support proliferation following perturbation of homeostasis - Cell Reports
Effects of acute cannabidiol on behavior and the endocannabinoid system in HIV-1 Tat transgenic female and male mice - Frontiers in Neuroscience
Childhood cancer mutagenesis caused by transposase-derived PGBD5 - Science advances
Glomerular Elasticity and Gene Expression Patterns Define Two Phases of Alport Nephropathy - bioRxiv
Preeclampsia in mice carrying fetuses with APOL1 risk variants - bioRxiv
Kit Ligand and Kit receptor tyrosine kinase sustain synaptic inhibition of Purkinje cells - Elife
CD47 is Required for Mesenchymal Progenitor Proliferation and Fracture Repair - bioRxiv : the preprint server for biology
Investigating the Role of Lysosomal Acid Lipase (LAL) in the Skeletal Niche - marshallplan.at
Efferocytosis reprograms the tumor microenvironment to promote pancreatic cancer liver metastasis - Nature cancer
MicroRNA-409-3p/BTG2 signaling axis improves impaired angiogenesis and wound healing in obese mice - FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Integrin-αvβ6 targeted peptide-toxin therapy in a novel αvβ6-expressing immunocompetent model of pancreatic cancer - Pancreatology
Investigating the impact of lung cancer cell-of-origin on tumour metabolic phenotype and heterogeneity - Thesis
Optical Imaging Demonstrates Tissue-Specific Metabolic Perturbations in Mblac1 Knockout Mice - IEEE journal of translational engineering in health and medicine
Effects of Paraquat, Dextran Sulfate Sodium, and Irradiation on Behavioral and Cognitive Performance and the Gut Microbiome in A53T and A53T-L444P Mice - Genes
Mapping changes in uterine contractility during the ovulatory cycle with wide-area calcium imaging in live mice - bioRxiv : the preprint server for biology
Jag1 represses Notch activation in lateral supporting cells and inhibits an outer hair cell fate in the medial compartment of the developing cochlea - bioRxiv
Photonic neural probe enabled microendoscopes for light-sheet light-field computational fluorescence brain imaging - Neurophotonics
The presence of xanthine dehydrogenase is crucial for the maturation of the rat kidneys - Clinical science (London, England : 1979)
Donor template delivery by recombinant adeno-associated virus for the production of knock-in mice - BMC biology
Optimal transcorneal electrical stimulation parameters for preserving photoreceptors in a mouse model of retinitis pigmentosa - Neural Regeneration Research
Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-specific Neutrophils - Cancer research communications
Focused Ultrasound Blood-Brain Barrier Opening Arrests the Growth and Formation of Cerebral Cavernous Malformations - bioRxiv : the preprint server for biology
A targetable PREX2/RAC1/PI3Kβ signalling axis confers resistance to clinically relevant therapeutic approaches in melanoma - bioRxiv
A parabrachial hub for the prioritization of survival behavior - bioRxiv
Zebrafish reveal new roles for Fam83f in hatching and the DNA damage-mediated autophagic response - bioRxiv
Cardiomyocyte PGC-1α enables physiological adaptations to endurance exercise through suppression of GDF15 and cardiac atrophy - bioRxiv
Structure-guided engineering of a fast genetically encoded sensor for real-time H2O2 monitoring - bioRxiv : the preprint server for biology
Clonal Hematopoiesis of Indeterminate Potential With Loss of Tet2 Enhances Risk for Atrial Fibrillation Through Nlrp3 Inflammasome Activation - Circulation
The metabolically protective energy expenditure increase ofPik3r1-related insulin resistance is not explained by Ucp1-mediated thermogenesis - bioRxiv
Framework for in vivo T cell screens - The Journal of experimental medicine
Parvalbumin Interneuron Impairment Leads to Synaptic Transmission Deficits and Seizures inSCN8AEpileptic Encephalopathy - bioRxiv
Translation of secretory mRNAs must be restrained during early oncogenesis to permit hepatocellular carcinoma initiation - Research Square
Mutation of novel ethanol-responsive lncRNA Gm41261 impacts ethanol-related behavioral responses in mice - Genes, brain, and behavior
Inactivation of phosphodiesterase-4B gene in rat nucleus accumbens shell by CRISPR/Cas9 or positive allosteric modulation of the protein affects the motivation to chronically self-administer nicotine - Scientific Reports
Cell type-specific expression, regulation and compensation of CDKL5 activity in mouse brain - Molecular Psychiatry
Intercalated amygdala dysfunction drives extinction deficits in theSapap3mouse model of obsessive-compulsive disorder - bioRxiv
Dorsal motor vagal neurons can elicit bradycardia and reduce anxiety-like behavior - iScience
Quantifying forms and functions of intestinal bile acid pools in mice - bioRxiv : the preprint server for biology
Unveiling Frailty: Comprehensive and Sex-Specific Characterization in Prematurely Aging PolgA Mice - bioRxiv
ACAD10 is not required for metformin's metabolic actions or for maintenance of whole-body metabolism in C57BL/6J mice - Diabetes, obesity & metabolism
Regulation of IFNγ production by ZFP36L2 in T cells is context-dependent - bioRxiv
Plural molecular and cellular mechanisms of pore domain KCNQ2 encephalopathy - bioRxiv : the preprint server for biology
Traumatic Brain Injury Induces Nociceptin/Orphanin FQ and Nociceptin Opioid Peptide Receptor Expression within 24 Hours - International Journal of Molecular Sciences
The Gut Microbiome Controls Liver Tumors via the Vagus Nerve - bioRxiv
Targeted deletion of NR2F2 and VCAM1 in theca cells impacts ovarian follicular development: insights into PCOS? - Biology of reproduction
Mitochondrial calcium transport during autophagy initiation - Mitochondrial Communications
Automated behavioral analysis reveals that mice employ a bait-and-switch escape mechanism to de-escalate social conflict - bioRxiv : the preprint server for biology
Repopulated spinal cord microglia exhibit a unique transcriptome and contribute to pain resolution - Cell Reports
Overexpression of the schizophrenia risk gene C4 in PV cells drives sex-dependent behavioral deficits and circuit dysfunction - bioRxiv
Human IL-6 fosters long-term engraftment of patient derived disease-driving myeloma cells in immunodeficient mice - bioRxiv
Methods to study xenografted human cancer in genetically diverse mice - bioRxiv
A heart derived-soluble factor which controls kidney and cardiovascular function after acute cardiorenal syndrome - Research Square
Dichotomous role of the serine/threonine kinase MAP4K4 in pancreatic ductal adenocarcinoma onset and metastasis through control of AKT and ERK pathways - The Journal of pathology
Nestin-expressing cells are mitotically active in the mammalian inner ear - Hearing Research
Endogenous glucocorticoids are required for normal macrophage activation and gastric Helicobacter pylori immunity - bioRxiv : the preprint server for biology
The MYPT2-regulated striated muscle-specific myosin light chain phosphatase limits cardiac myosin phosphorylation in vivo - The Journal of biological chemistry
Metabolism-Regulating Nanozyme System for Advanced Nanocatalytic Cancer Therapy - Small (Weinheim an der Bergstrasse, Germany)
Mice with an autism-associated R451C mutation in neuroligin-3 show intact attention orienting but atypical responses to methylphenidate and atomoxetine in the mouse-Posner task - Psychopharmacology
Super-resolution ultrasound reveals cerebrovascular impairment in a mouse model of Alzheimer's Disease - The Journal of neuroscience : the official journal of the Society for Neuroscience
SARS-CoV-2 papain-like protease activates nociceptors to drive sneeze and pain - bioRxiv : the preprint server for biology
Behavioral, metabolic, and lipidomic characterization of the 5xFADxTg30 mouse model of Alzheimer's disease - iScience
Extracellular Matrix Orchestration of Tissue Remodeling in the Chronically Inflamed Mouse Colon - Cellular and Molecular Gastroenterology and Hepatology
KRAS allelic imbalance drives tumour initiation yet suppresses metastasis in colorectal cancer in vivo - Nature Communications
Anti-hyperalgesic and anti-inflammatory effects of 4R-tobacco cembranoid in a mouse model of inflammatory pain - Journal of inflammation (London, England)
Hippocampus Glutathione S Reductase Potentially Confers Genetic Resilience to Cognitive Decline in the AD-BXD Mouse Population - bioRxiv : the preprint server for biology
Accelerated neurodegeneration of basal forebrain cholinergic neurons in HIV-1 gp120 transgenic mice: Critical role of the p75 neurotrophin receptor - Brain, Behavior, and Immunity
CREB activation drives acinar to ductal reprogramming and promote pancreatic cancer progression in animal models of alcoholic chronic pancreatitis - bioRxiv
Empirically derived formulae for calculation of age- and region-related levels of iron, copper and zinc in the adult C57BL/6 mouse brain - Neurobiology of Aging
Deletion of Aurora kinase A prevents the development of polycystic kidney disease in mice - Nature Communications
Development of a mouse model expressing a bifunctional glutathione synthesizing enzyme to study glutathione limitation in vivo - The Journal of biological chemistry
A mouse model to study glutathione limitation in vivo - bioRxiv : the preprint server for biology
Levodopa Rescues Retinal Function in the Transgenic A53T Alpha-Synuclein Model of Parkinson's Disease - Biomedicines
LOXHD1 is indispensable for coupling auditory mechanosensitive channels to the site of force transmission - Research Square
Notch receptor-ligand binding facilitates extracellular vesicle-mediated neuron-to-neuron communication - Cell Reports
Contributions of Mouse Genetic Strain Background to Age-Related Phenotypes in Physically Active HET3 Mice - Neurobiology of Aging
BACH1 promotes tissue necrosis and Mycobacterium tuberculosis susceptibility - Nature Microbiology
Microglia promote remyelination independent of their role in clearing myelin debris - Cell Reports
A mitochondrial inside-out iron-calcium signal reveals drug targets for Parkinson's disease - Cell Reports
Fenfluramine increases survival and reduces markers of neurodegeneration in a mouse model of Dravet syndrome - Epilepsia open
Paternally-induced environmental programming of placenta development, offspring birth weight and health phenotypes in a mouse model - bioRxiv
Small extracellular vesicles-transported lncRNA TDRKH-AS1 derived from AOPPs-treated trophoblasts initiates endothelial cells pyroptosis through PDIA4/DDIT4 axis in preeclampsia - Journal of Translational Medicine
Interleukin-17-mediated protective cytokine signaling against degeneration of the retinal pigment epithelium - Proceedings of the National Academy of Sciences of the United States of America
APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread - Cell
The intracellular C-terminus confers compartment-specific targeting of voltage-gated Ca2+channels - bioRxiv
YAP and TAZ couple osteoblast precursor mobilization to angiogenesis and mechanoregulation in murine bone development - Developmental Cell
Cystatin F (Cst7) drives sex-dependent changes in microglia in an amyloid-driven model of Alzheimer's disease - Elife
Gut microbiota depletion minimally affects the daily voluntary wheel running activity and food anticipatory activity in female and male C57BL/6J mice - Frontiers in Physiology
Senolytic Intervention Improves Cognition, Metabolism, and Adiposity in Female APP NL-F/NL-F Mice - bioRxiv : the preprint server for biology
Altered Hippocampal Glutamatergic Neurotransmission and Cognitive Impairment in APP Knock-In Mice - bioRxiv : the preprint server for biology
Systems genetics uncover new loci containing functional gene candidates inMycobacterium tuberculosis-infected Diversity Outbred mice - bioRxiv
Microsomal triglyceride transfer protein is necessary to maintain lipid homeostasis and retinal function - bioRxiv : the preprint server for biology
Commensal bacteria maintain a Qa-1b-restricted unconventional CD8+ T population in gut epithelium - Elife
Opioid-induced hyperalgesia and tolerance are driven by HCN ion channels - The Journal of neuroscience : the official journal of the Society for Neuroscience
Investigating the neuroimmunomodulatory effects of 40Hz light flicker treatment in 5xFAD model of Alzheimer's Disease - Thesis
Microprism-based two-photon imaging of the mouse inferior colliculus reveals novel organizational principles of the auditory midbrain - Elife
Soluble PD-L1 reprograms blood monocytes to prevent cerebral edema and facilitate recovery after ischemic stroke - Brain, Behavior, and Immunity
Dopamine neuron activity evoked by sucrose and sucrose-predictive cues is augmented by peripheral and central manipulations of glucose availability - The European journal of neuroscience
The flow of axonal information among hippocampal sub-regions 2: patterned stimulation sharpens routing of information transmission - Frontiers in Neural Circuits
Filipin complex-reactive brain lesions: a cautionary tale - Neuropathology and applied neurobiology
Understanding the Effects of Ageing on B cells Response to Vaccination - Thesis
Clonal hematopoiesis related TET2 loss-of-function impedes IL1β-mediated epigenetic reprogramming in hematopoietic stem and progenitor cells - Nature Communications
AAV-mediated interneuron-specific gene replacement for Dravet syndrome - bioRxiv : the preprint server for biology
The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent - Cell Reports
Ultrasound Modulates Calcium Activity in Cultured Neurons, Glial Cells, Endothelial Cells and Pericytes - Ultrasound in medicine & biology
Structural and functional rescue of cones carrying the most common cone opsin C203R missense mutation - JCI Insight
Reconstitution of the phosphodiesterase 6 maturation process important for photoreceptor cell function - The Journal of biological chemistry
AMP-activated protein kinase is necessary for Treg cell functional adaptation to microenvironmental stress - bioRxiv : the preprint server for biology
Single-fraction Radiation Treatment Dose Response in a Genetically Engineered Mouse Model of Medulloblastoma - Radiation Research
Microglial-specific knockdown of iron import gene, Slc11a2, blunts LPS-induced neuroinflammatory responses in a sex-specific manner - Brain, Behavior, and Immunity
An integrated workflow for 2D and 3D posture analysis during vestibular system testing in mice - Frontiers in Neurology
Tumor-selective effects of active RAS inhibition in pancreatic ductal adenocarcinoma - bioRxiv : the preprint server for biology
SPINAL V1 INHIBITORY INTERNEURON CLADES DIFFER IN BIRTHDATE, PROJECTIONS TO MOTONEURONS AND HETEROGENEITY - bioRxiv : the preprint server for biology
Diroximel fumarate acts through Nrf2 to attenuate methylglyoxal-induced nociception in mice and decreases ISR activation in DRG neurons - bioRxiv
Evidence for prodromal changes in neuronal excitability and neuroinflammation in the hippocampus in young alpha-synuclein (A30P) transgenic mice - Frontiers in Dementia
Malic enzyme 1 knockout has no deleterious phenotype and is favored in the male germline under standard laboratory conditions - PLOS ONE
Intra-organ cell specific mitochondrial quantitative interactomics - bioRxiv : the preprint server for biology
BMAL1 sex-specific effects in the neonatal mouse airway exposed to moderate hyperoxia - Physiological Reports
CD8+ T cell-derived Fgl2 regulates immunity in a cell-autonomous manner via ligation of FcγRIIB - Nature Communications
AAV-mediated gene transfer of WDR45 corrects neurologic deficits in the mouse model of beta-propeller protein-associated neurodegeneration - bioRxiv
In vivo Targeting MEK and TNK2/SRC pathways in PTPN11 driven leukemia - bioRxiv : the preprint server for biology
Epidermal growth factor augments the self-renewal capacity of aged hematopoietic stem cells - iScience
SLC38A9 regulates SARS-CoV-2 viral entry - iScience
Developmental and therapeutic implications of IL4ra expression for rhabdomyosarcoma - Transgenic Research
Elucidating the Role of IgA in Allergic Disease - Thesis
Microglial mitochondria: defining the landscape and testing links between organelle remodeling and microglial function - Thesis
Primary cilia as a targetable node between biliary injury, senescence and regeneration in liver transplantation - Journal of hepatology
Systems genetics uncover new loci containing functional gene candidates in Mycobacterium tuberculosis-infected Diversity Outbred mice - PLoS Pathogens
Biomechanical dysregulation of SGK-1 dependent aortic pathologic markers in hypertension - Frontiers in cardiovascular medicine
Early life adversity promotes gastrointestinal dysfunction through a sex-dependent phenotypic switch in enteric glia - bioRxiv : the preprint server for biology
Caspase-8-mediated inflammation but not apoptosis drives death of retinal ganglion cells and loss of visual function in glaucomaa - Research Square
Loss of ARID1A accelerates prostate tumourigenesis with a proliferative collagen-poor phenotype through co-operation with AP1 subunit cFos - bioRxiv
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling - Nature Communications
Cerebral ischaemic stroke results in altered mucosal IgA responses and host-commensal microbiota interactions - bioRxiv
Collaboration between IL-7 and IL-15 enables adaptation of tissue-resident and circulating memory CD8+ T cells - bioRxiv : the preprint server for biology
Individual NMDA receptor GluN2 subunit signaling domains differentially regulate the postnatal maturation of hippocampal excitatory synaptic transmission and plasticity but not dendritic morphology - Synapse (New York, N.Y.)
Desmosine Content and Passive Mechanics of the Elastic Fiber Deficient Murine Uterus - Tulane Undergraduate Research Journal
IN SEARCH OF MOUSE MODELS FOR EXFOLIATION SYNDROME - American journal of ophthalmology
Adult-born granule cells modulate CA2 network activity during retrieval of developmental memories of the mother - Elife
Overexpression of enhanced yellow fluorescent protein fused with Channelrhodopsin-2 causes contractile dysfunction in skeletal muscle - bioRxiv
Age-related differences in retinal function and structure in C57BL/6J and Thy1-YFPh mice - Neurobiology of Aging
ATP-dependent citrate lyase Drives Left Ventricular Dysfunction by Metabolic Remodeling of the Heart - bioRxiv : the preprint server for biology
Hypertension increases sympathetic neuron activity by enhancing intraganglionic cholinergic collateral connections - The Journal of Physiology
FOXP3+ Regulatory T Cells Require TBET to Regulate Activated CD8+ T Cells During Recovery from Influenza Infection - bioRxiv : the preprint server for biology
Myocardial SERCA2 Protects Against Cardiac Damage and Dysfunction Caused by Inhaled Bromine - The Journal of pharmacology and experimental therapeutics
Neuron specific quantitation of Gαolf expression and signaling in murine brain tissue - Brain Research
Intraperitoneal activation of myeloid cells clears ascites and reveals IL27-dependent regression of metastatic ovarian cancer - bioRxiv
Thalamocortical mGlu8 Modulates Dorsal Thalamus Excitatory Transmission and Sensorimotor Activity - The Journal of neuroscience : the official journal of the Society for Neuroscience
Cognitive behavioral phenotyping of DSCAM heterozygosity as a model for autism spectrum disorder - bioRxiv : the preprint server for biology
Dietary intervention rescues a bone porosity phenotype in a murine model of Neurofibromatosis Type 1 (NF1) - PLOS ONE
Rapidly reversible persistent long-term potentiation inhibition by patient-derived brain tau and amyloid ß proteins - Philosophical transactions of the Royal Society of London. Series B, Biological sciences
Assessment of Antimicrobial Therapy in EradicatingChlamydia muridarumin Research Mice: Immune Status and its Impact on Outcomes - bioRxiv
Notch signaling regulates UNC5B to suppress endothelial proliferation, migration, junction activity, and retinal plexus branching - Scientific Reports
Knockdown of microglial iron import gene, DMT1, worsens cognitive function and alters microglial transcriptional landscape in a sex-specific manner in the APP/PS1 model of Alzheimer’s disease - Research Square
Deficiency of glucocorticoid receptor in bone marrow adipocytes has mild effects on bone and hematopoiesis but does not influence expansion of marrow adiposity with caloric restriction - Frontiers in endocrinology
Enhanced hippocampal LTP but normal NMDA receptor and AMPA receptor function in a rat model of CDKL5 deficiency disorder - Molecular autism
Human-Mouse Neural Crest Chimeras as a Novel Model for Human Melanocyte Biology in Development and Disease - Thesis
Characterization of the effects of cannabinoid receptor deletion on energy metabolism in female C57BL mice - Frontiers in endocrinology
Overexpression of the receptor for resolvin E1 (ERV1) prevents early alveolar bone loss in leptin receptor deficiency‐induced diabetes - Journal of Periodontology
Conserved long noncoding RNA TILAM promotes liver fibrosis through interaction with PML in HSCs - Hepatology (Baltimore, Md.)
POMC neurons control fertility through differential signaling of MC4R in Kisspeptin neurons - bioRxiv : the preprint server for biology
Changes in the chikungunya virus E1 glycoprotein domain II and hinge influence E2 conformation, infectivity, and virus-receptor interactions - Journal of Virology
Endogenous p53 inhibitor TIRR dissociates systemic metabolic health from oncogenic activity - Cell Reports
Examining the Effects of Light Pollution on Health and Diseases - Thesis
Effects of ethanol on social-induced neural activity in a rat model of autism spectrum disorder - Thesis
Elucidating the mechano-molecular dynamics of TRAP activity using CRISPR/Cas9 mediated fluorescent reporter mice - Heliyon
Resistance to Spindle Inhibitors in Glioblastoma Depends on STAT3 and Therapy Induced Senescence - bioRxiv : the preprint server for biology
MERTK INDUCES TOLEROGENIC DENDRITIC CELLS BY METABOLIC REPROGRAMMING - Thesis
Elucidation of the role of methylarginine metabolism in regulation of nitric oxide production and inflammation - Thesis
SOX2 drives fetal reprogramming and reversible dormancy in colorectal cancer - bioRxiv
Oscillatory-Quality of sleep spindles links brain state with sleep regulation and function - Science advances
Loss of DOCK2 potentiates Inflammatory Bowel Disease-associated colorectal cancer via immune dysfunction and IFNγ induction of IDO1 expression - Oncogene
Deletion of the WD40 domain of ATG16L1 exacerbates acute pancreatitis, abolishes LAP-like non-canonical autophagy and slows trypsin degradation - Autophagy
Expression of anti-amyloid CARs in microglia promotes efficient and selective phagocytosis of Aβ1‒42 - Research Square
nSMase2-mediated exosome secretion shapes the tumor microenvironment to immunologically support pancreatic cancer - bioRxiv
Exploring the structure, metabolism, and biochemistry of the neuronal microenvironment label-free using fast simultaneous multimodal optical microscopy - Optica
Glucocorticoid Receptor Signaling Is Critical for Mouse Corneal Development, Inhibition of Inflammatory Response, and Neovascularization of the Cornea - The American journal of pathology
Behavioral regression in shank3Δex4-22 mice during early adulthood corresponds to cerebellar granule cell glutamatergic synaptic changes - Research Square
Whisker deprivation triggers a distinct form of cortical homeostatic plasticity that is impaired in theFmr1KO - bioRxiv
Adaptive protein synthesis in genetic models of copper deficiency and childhood neurodegeneration - bioRxiv : the preprint server for biology
Gut microbiome and inflammation in response to increasing intermittent hypoxia in the neonatal rat - Pediatric research
Sleep loss-induced oncogenic pathways are mediated via the neuron-specific interleukin-1 receptor accessory protein (AcPb) - Brain, Behavior, and Immunity
Sex-Specific Roles of Hypocretin Receptor Signaling in CRF Neurons on Alcohol Drinking, Anxiety, and BNST Neuronal Excitability - bioRxiv : the preprint server for biology
Flagellum-deficient Pseudomonas aeruginosa is more virulent than non-motile but flagellated mutants in a cystic fibrosis mouse model - Microbiology spectrum
The ROCK-1/2 inhibitor RKI-1447 blocks N-MYC, promotes cell death, and emerges as a synergistic partner for BET inhibitors in neuroblastoma - Cancer letters
Synaptic integration of somatosensory and motor cortical inputs onto spiny projection neurons of mice caudoputamen - The European journal of neuroscience
The amino acid transporter SLC7A5 drives progression of PI3K-mutant intestinal cancer models and enhances response to MAPK-targeted therapy - Research Square
Next generation vaccines against respiratory pathogens: lessons from SARS CoV2 and Bordetella pertussis - Thesis
The ventral tegmental area dopamine to basolateral amygdala projection supports acquisition of cocaine self-administration - Neuropharmacology
The prion protein is required for normal responses to light stimuli by photoreceptors and bipolar cells - iScience
Sex-dependent regulation of retinal pigment epithelium and retinal function by Pgc-1α - Frontiers in Cellular Neuroscience
Targeting Cell Signaling Pathways to Modulate the Foreign Body Response for Medical Device and Tissue Engineering Applications - Thesis
The Relationship Between Metabolism and Calcium in Producing Islet Pulsatility - Thesis
Cortical and subcortical glial cells undergo rapid changes following acute chemogenetic manipulation of a subpopulation of layer 5 projection neurons - Research Square